Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
about
Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target ProteinRepair of oxidative DNA damage and cancer: recent progress in DNA base excision repairHuman AP endonuclease 1: a potential marker for the prediction of environmental carcinogenesis riskConserved Structural Chemistry for Incision Activity in Structurally Non-homologous Apurinic/Apyrimidinic Endonuclease APE1 and Endonuclease IV DNA Repair EnzymesRedox homeostasis: the linchpin in stem cell self-renewal and differentiationAPE1/Ref-1 regulates STAT3 transcriptional activity and APE1/Ref-1-STAT3 dual-targeting effectively inhibits pancreatic cancer cell survivalProteomic study of amyloid beta (25-35) peptide exposure to neuronal cells: Impact on APE1/Ref-1's protein-protein interactionUbiquitination of human AP-endonuclease 1 (APE1) enhanced by T233E substitution and by CDK5.Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.Novel small-molecule inhibitor of apurinic/apyrimidinic endonuclease 1 blocks proliferation and reduces viability of glioblastoma cells.The many functions of APE1/Ref-1: not only a DNA repair enzymeDesign and synthesis of novel quinone inhibitors targeted to the redox function of apurinic/apyrimidinic endonuclease 1/redox enhancing factor-1 (Ape1/ref-1).Cardiac Cell Senescence and Redox Signaling.DNA damage related crosstalk between the nucleus and mitochondria.Redox regulation of DNA repair: implications for human health and cancer therapeutic development.APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functionsPosttranslational modification of mammalian AP endonuclease (APE1).High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I.Inhibition of the redox function of APE1/Ref-1 in myeloid leukemia cell lines results in a hypersensitive response to retinoic acid-induced differentiation and apoptosis.Redox regulation of apurinic/apyrimidinic endonuclease 1 activity in Long-Evans Cinnamon rats during spontaneous hepatitisFunctional analysis of novel analogues of E3330 that block the redox signaling activity of the multifunctional AP endonuclease/redox signaling enzyme APE1/Ref-1.Interactions of apurinic/apyrimidinic endonuclease with a redox inhibitor: evidence for an alternate conformation of the enzyme.Functional assessment of population and tumor-associated APE1 protein variantsA novel regulatory circuit in base excision repair involving AP endonuclease 1, Creb1 and DNA polymerase beta.Base excision repair apurinic/apyrimidinic endonucleases in apicomplexan parasite Toxoplasma gondiiCloning and characterization of a wheat homologue of apurinic/apyrimidinic endonuclease Ape1LThe repair function of the multifunctional DNA repair/redox protein APE1 is neuroprotective after ionizing radiation.Impact of APE1/Ref-1 redox inhibition on pancreatic tumor growthKnock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and functionApurinic/Apyrimidinic endonuclease 1 regulates inflammatory response in macrophages.Mitochondrial translocation of APE1 relies on the MIA pathway.Characterization of the redox activity and disulfide bond formation in apurinic/apyrimidinic endonuclease.APE1/Ref-1 role in redox signaling: translational applications of targeting the redox function of the DNA repair/redox protein APE1/Ref-1.APE1, the DNA base excision repair protein, regulates the removal of platinum adducts in sensory neuronal cultures by NERS-glutathionylation of cysteine 99 in the APE1 protein impairs abasic endonuclease activity.Molecular cloning and 3D structure modeling of APEX1, DNA base excision repair enzyme from the Camel, Camelus dromedariusRole of the multifunctional DNA repair and redox signaling protein Ape1/Ref-1 in cancer and endothelial cells: small-molecule inhibition of the redox function of Ape1Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Regulation of limited N-terminal proteolysis of APE1 in tumor via acetylation and its role in cell proliferation.Apurinic/apyrimidinic endonuclease 1 alters estrogen receptor activity and estrogen-responsive gene expression.
P2860
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P2860
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@ast
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@en
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@nl
type
label
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@ast
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@en
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@nl
prefLabel
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@ast
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@en
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@nl
P2093
P2860
P3181
P1433
P1476
Evolution of the redox function in mammalian apurinic/apyrimidinic endonuclease
@en
P2093
P2860
P3181
P356
10.1016/J.MRFMMM.2008.04.008
P407
P577
2008-08-25T00:00:00Z