Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease - Wikidata - awgldk - TriplyDB

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease

Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease

http://www.wikidata.org/entity/Q24534813

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Glatiramer acetate reduces the risk for experimental cerebral malaria: a pilot study Immunotherapy as treatment for Alzheimer’s disease Immunization with amyloid-beta attenuates inclusion body myositis-like myopathology and motor impairment in a transgenic mouse model Active and passive immunotherapy for neurodegenerative disorders Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1 T cells in the central nervous system: messengers of destruction or purveyors of protection?MicroRNAs are universal regulators of differentiation, activation, and polarization of microglia and macrophages in normal and diseased CNS Therapeutic effects of glatiramer acetate and grafted CD115⁺ monocytes in a mouse model of Alzheimer's disease.Glatiramer acetate in the treatment of multiple sclerosis: emerging concepts regarding its mechanism of action Neuroprotective and neurotoxic properties of glial cells in the pathogenesis of Alzheimer's disease Rett syndrome and other autism spectrum disorders--brain diseases of immune malfunction?Abeta-induced meningoencephalitis is IFN-gamma-dependent and is associated with T cell-dependent clearance of Abeta in a mouse model of Alzheimer's disease.Molecular mechanisms for Alzheimer's disease: implications for neuroimaging and therapeutics.T cells specifically targeted to amyloid plaques enhance plaque clearance in a mouse model of Alzheimer's disease Abnormal changes in NKT cells, the IGF-1 axis, and liver pathology in an animal model of ALS.Targeting progressive neuroaxonal injury: lessons from multiple sclerosis.CNS expression of anti-inflammatory cytokine interleukin-4 attenuates Alzheimer's disease-like pathogenesis in APP+PS1 bigenic mice Small molecule blockers of the Alzheimer Abeta calcium channel potently protect neurons from Abeta cytotoxicity.Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Abeta immunotherapy.Immunotherapy of cerebrovascular amyloidosis in a transgenic mouse model Activation of microglia acidifies lysosomes and leads to degradation of Alzheimer amyloid fibrils.VGF expression by T lymphocytes in patients with Alzheimer's disease Brain Uptake of Neurotherapeutics after Intranasal versus Intraperitoneal Delivery in Mice.Motor neuron-immune interactions: the vicious circle of ALS.Immunization therapy in Alzheimer's disease.Exercise alters the immune profile in Tg2576 Alzheimer mice toward a response coincident with improved cognitive performance and decreased amyloid Disease modifying therapy for AD?100 years and counting: prospects for defeating Alzheimer's disease Current experimental therapy for Alzheimer's disease Reversal of paralysis and reduced inflammation from peripheral administration of β-amyloid in TH1 and TH17 versions of experimental autoimmune encephalomyelitis.Scara1 deficiency impairs clearance of soluble amyloid-β by mononuclear phagocytes and accelerates Alzheimer's-like disease progression IFN-gamma promotes complement expression and attenuates amyloid plaque deposition in amyloid beta precursor protein transgenic mice.Thymic involution, a co-morbidity factor in amyotrophic lateral sclerosis.Immunization in Alzheimer's disease: naïve hope or realistic clinical potential?Modulation of innate immunity by copolymer-1 leads to neuroprotection in murine HIV-1 encephalitis.Imaging microglial activation during neuroinflammation and Alzheimer's disease.A nasal proteosome adjuvant activates microglia and prevents amyloid deposition.Microglia: key innate immune cells of the brain.Mechanisms of neurodegeneration shared between multiple sclerosis and Alzheimer's disease.The retina as a window to the brain-from eye research to CNS disorders.

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Nasal vaccination with a proteosome-based adjuvant and glatiramer acetate clears beta-amyloid in a mouse model of Alzheimer disease

http://www.wikidata.org/entity/Q24534813

description

2005 nî lūn-bûn

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2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2005 թվականի օգոստոսին հրատարակված գիտական հոդված

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Nasal vaccination with a prote ...... use model of Alzheimer disease

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Journal of Clinical Investigation

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Nasal vaccination with a prote ...... use model of Alzheimer disease

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Dan Frenkel

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David S Burt

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Howard L Weiner

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Ruth Maron

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P2860

Correlative Memory Deficits, Abeta Elevation, and Amyloid Plaques in Transgenic Mice

Therapeutic vaccine for acute and chronic motor neuron diseases: implications for amyotrophic lateral sclerosis.

The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeutics

Subacute meningoencephalitis in a subset of patients with AD after Abeta42 immunization

Copolymer 1 reduces relapse rate and improves disability in relapsing-remitting multiple sclerosis: results of a phase III multicenter, double-blind placebo-controlled trial. The Copolymer 1 Multiple Sclerosis Study Group

Reversible memory loss in a mouse transgenic model of Alzheimer's disease

High-level neuronal expression of abeta 1-42 in wild-type human amyloid protein precursor transgenic mice: synaptotoxicity without plaque formation

Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse

High affinity binding of monoclonal antibodies to the sequential epitope EFRH of beta-amyloid peptide is essential for modulation of fibrillar aggregation.

A beta peptide immunization reduces behavioural impairment and plaques in a model of Alzheimer's disease.

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10.1172/JCI23241

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9

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115

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Alzheimer's disease

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1184038

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