LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation
about
c-Src is a PDZ interaction partner and substrate of the E3 ubiquitin ligase Ligand-of-Numb protein X1Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with NumbModulation of Tcf3 repressor complex composition regulates cdx4 expression in zebrafishNp9 protein of human endogenous retrovirus K interacts with ligand of numb protein XLoss of negative regulation by Numb over Notch is relevant to human breast carcinogenesisThe Roles of RNase-L in Antimicrobial Immunity and the Cytoskeleton-Associated Innate ResponseThe role of targeted protein degradation in early neural developmentNon-traditional functions of ubiquitin and ubiquitin-binding proteinsLnx2 ubiquitin ligase is essential for exocrine cell differentiation in the early zebrafish pancreasOrganizer restriction through modulation of Bozozok stability by the E3 ubiquitin ligase Lnx-likeBiochemical and computational analysis of LNX1 interacting proteinsCommon variants on 14q32 and 13q12 are associated with DLBCL susceptibilityA high efficiency strategy for binding property characterization of peptide-binding domains.The Coxsackievirus and adenovirus receptor (CAR) forms a complex with the PDZ domain-containing protein ligand-of-numb protein-X (LNX).Sent to destroy: the ubiquitin proteasome system regulates cell signaling and protein quality control in cardiovascular development and disease.Numb proteins specify asymmetric cell fates via an endocytosis- and proteasome-independent pathway.Molecular evolution of the LNX gene familyThe functional role of Notch signaling in human gliomas.Mammalian numb proteins promote Notch1 receptor ubiquitination and degradation of the Notch1 intracellular domain.A novel transmembrane protein recruits numb to the plasma membrane during asymmetric cell division.Ubiquitylation and degradation of serum-inducible kinase by hVPS18, a RING-H2 type ubiquitin ligase.Osteopetrosis in TAK1-deficient mice owing to defective NF-κB and NOTCH signaling.Notch signaling in hematopoiesis and early lymphocyte development.Emerging molecular targets for the treatment of pre-eclampsia.UV-Induced Wnt7a in the Human Skin Microenvironment Specifies the Fate of Neural Crest-Like Cells via Suppression of Notch.Cargo- and compartment-selective endocytic scaffold proteins.Caspr4 interaction with LNX2 modulates the proliferation and neuronal differentiation of mouse neural progenitor cells.Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor ciliaNotch: a unique therapeutic target for immunomodulation.Np9, a cellular protein of retroviral ancestry restricted to human, chimpanzee and gorilla, binds and regulates ubiquitin ligase MDM2.The pineal gland: A model for adrenergic modulation of ubiquitin ligasesGenetic amplification of the NOTCH modulator LNX2 upregulates the WNT/β-catenin pathway in colorectal cancer.Structural basis for the indispensable role of a unique zinc finger motif in LNX2 ubiquitinationMicroRNAs and Glucocorticoid-Induced Apoptosis in Lymphoid MalignanciesNumb endocytic adapter proteins regulate the transport and processing of the amyloid precursor protein in an isoform-dependent manner: implications for Alzheimer disease pathogenesisAsymmetric localization of numb in the chick somite and the influence of myogenic signalsWhen MAGE meets RING: insights into biological functions of MAGE proteins.The cell fate determinant numb interacts with EHD/Rme-1 family proteins and has a role in endocytic recycling.Network Modeling Identifies Patient-specific Pathways in Glioblastoma.Mechanisms of ErbB receptor negative regulation and relevance in cancer.
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P2860
LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation
description
2002 nî lūn-bûn
@nan
2002 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
LNX functions as a RING type E ...... biquitin-dependent degradation
@ast
LNX functions as a RING type E ...... biquitin-dependent degradation
@en
LNX functions as a RING type E ...... biquitin-dependent degradation
@nl
type
label
LNX functions as a RING type E ...... biquitin-dependent degradation
@ast
LNX functions as a RING type E ...... biquitin-dependent degradation
@en
LNX functions as a RING type E ...... biquitin-dependent degradation
@nl
prefLabel
LNX functions as a RING type E ...... biquitin-dependent degradation
@ast
LNX functions as a RING type E ...... biquitin-dependent degradation
@en
LNX functions as a RING type E ...... biquitin-dependent degradation
@nl
P2093
P2860
P3181
P356
P1433
P1476
LNX functions as a RING type E ...... biquitin-dependent degradation
@en
P2093
C Jane McGlade
Cheryl D Wolting
Matt Dermer
Melanie A McGill
Sascha E Dho
P2860
P304
P3181
P356
10.1093/EMBOJ/21.1.93
P407
P577
2002-01-15T00:00:00Z