NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system.
about
IA1 is NGN3-dependent and essential for differentiation of the endocrine pancreas.INSM1 functions as a transcriptional repressor of the neuroD/beta2 gene through the recruitment of cyclin D1 and histone deacetylasesZinc finger transcription factor INSM1 interrupts cyclin D1 and CDK4 binding and induces cell cycle arrestIdentification of an INSM1-binding site in the insulin promoter: negative regulation of the insulin gene transcriptionA central role for Islet1 in sensory neuron development linking sensory and spinal gene regulatory programsHigh-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disordersThe zinc-finger factor Insm1 (IA-1) is essential for the development of pancreatic beta cells and intestinal endocrine cellsStructure, expression, and biological function of INSM1 transcription factor in neuroendocrine differentiation.INSM1 promoter-driven adenoviral herpes simplex virus thymidine kinase cancer gene therapy for the treatment of primitive neuroectodermal tumorsInsulinoma-associated antigen-1 zinc-finger transcription factor promotes pancreatic duct cell trans-differentiation.EVOPRINTER, a multigenomic comparative tool for rapid identification of functionally important DNAXenopus insm1 is essential for gastrointestinal and pancreatic endocrine cell development.Expression of insulinoma-associated 2 (INSM2) in pancreatic islet cells is regulated by the transcription factors Ngn3 and NeuroD1Microarray analysis of XOPS-mCFP zebrafish retina identifies genes associated with rod photoreceptor degeneration and regeneration.A homozygous missense mutation in NEUROD1 is associated with nonsyndromic autosomal recessive retinitis pigmentosa.Herpes simplex virus induces the marked up-regulation of the zinc finger transcriptional factor INSM1, which modulates the expression and localization of the immediate early protein ICP0.Cross-talk between distinct nuclear import pathways enables efficient nuclear import of E47 in conjunction with its partner transcription factorsFunctional role of an islet transcription factor, INSM1/IA-1, on pancreatic acinar cell trans-differentiationNeurogenin 3 recruits CBP co-activator to facilitate histone H3/H4 acetylation in the target gene INSM1.An integrated approach identifies Nhlh1 and Insm1 as Sonic Hedgehog-regulated genes in developing cerebellum and medulloblastomaSnail/Gfi-1 (SNAG) family zinc finger proteins in transcription regulation, chromatin dynamics, cell signaling, development, and diseaseAdenoviral insulinoma-associated protein 1 promoter-driven suicide gene therapy with enhanced selectivity for treatment of neuroendocrine cancers.Insm1 (IA-1) is an essential component of the regulatory network that specifies monoaminergic neuronal phenotypes in the vertebrate hindbrain.Extra-nuclear activity of INSM1 transcription factor enhances insulin receptor signaling pathway and Nkx6.1 expression through RACK1 interaction.Understanding how differentiation is maintained: lessons from the Drosophila brain.Transcriptional regulatory events initiated by Ascl1 and Neurog2 during neuronal differentiation of P19 embryonic carcinoma cells.Modifications to the INSM1 promoter to preserve specificity and activity for use in adenoviral gene therapy of neuroendocrine carcinomas.Pitt-Hopkins syndrome-associated mutations in TCF4 lead to variable impairment of the transcription factor function ranging from hypomorphic to dominant-negative effects.The Drosophila nerfin-1 mRNA requires multiple microRNAs to regulate its spatial and temporal translation dynamics in the developing nervous system.Directly reprogramming fibroblasts into adipogenic, neurogenic and hepatogenic differentiation lineages by defined factors.Transcriptional regulation of human MAP2 gene in melanoma: role of neuronal bHLH factors and Notch1 signaling.Insm1a Is Required for Zebrafish Posterior Lateral Line Development.Conserved sequence block clustering and flanking inter-cluster flexibility delineate enhancers that regulate nerfin-1 expression during Drosophila CNS development.Expression of the insulinoma-associated 1 (insm1) gene in Xenopus laevis tadpole retina and brain.Transient inactivation of Notch signaling synchronizes differentiation of neural progenitor cells.cis-Decoder discovers constellations of conserved DNA sequences shared among tissue-specific enhancers.Insm1 promotes the transition of olfactory progenitors from apical and proliferative to basal, terminally dividing and neuronogenic.Insulinoma-associated 1: A novel nuclear marker in Merkel cell carcinoma (cutaneous neuroendocrine carcinoma).Insulinoma-associated protein 1 (INSM1) is a useful marker for pancreatic neuroendocrine tumor.
P2860
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P2860
NeuroD1/E47 regulates the E-box element of a novel zinc finger transcription factor, IA-1, in developing nervous system.
description
2003 nî lūn-bûn
@nan
2003 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2003 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2003年の論文
@ja
2003年論文
@yue
2003年論文
@zh-hant
2003年論文
@zh-hk
2003年論文
@zh-mo
2003年論文
@zh-tw
2003年论文
@wuu
name
NeuroD1/E47 regulates the E-bo ...... , in developing nervous system
@nl
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@ast
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@en
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@en-gb
type
label
NeuroD1/E47 regulates the E-bo ...... , in developing nervous system
@nl
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@ast
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@en
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@en-gb
prefLabel
NeuroD1/E47 regulates the E-bo ...... , in developing nervous system
@nl
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@ast
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@en
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@en-gb
P2093
P2860
P356
P1476
NeuroD1/E47 regulates the E-bo ...... in developing nervous system.
@en
P2093
Mary B Breslin
Michael S Lan
P2860
P304
38991-38997
P356
10.1074/JBC.M306795200
P407
P577
2003-07-30T00:00:00Z