The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
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Stimulation of flap endonuclease-1 by the Bloom's syndrome proteinHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1Functional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D)Human exonuclease 1 and BLM helicase interact to resect DNA and initiate DNA repairThe Bloom's syndrome helicase suppresses crossing over during homologous recombinationRecQ helicases: caretakers of the genomeTopoisomerase IIIalpha is required for normal proliferation and telomere stability in alternative lengthening of telomeres.Drosophila melanogaster topoisomerase IIIalpha preferentially relaxes a positively or negatively supercoiled bubble substrate and is essential during development.Mechanisms by which Bloom protein can disrupt recombination intermediates of Okazaki fragment maturation.The HRDC domain of BLM is required for the dissolution of double Holliday junctionsMeiotic recombination intermediates are resolved with minimal crossover formation during return-to-growth, an analogue of the mitotic cell cyclePhosphorylation of BLM, dissociation from topoisomerase IIIalpha, and colocalization with gamma-H2AX after topoisomerase I-induced replication damage.Junction of RecQ helicase biochemistry and human disease.The dissolution of double Holliday junctions.DNA topoisomerase III localizes to centromeres and affects centromeric CENP-A levels in fission yeast.The absence of Top3 reveals an interaction between the Sgs1 and Pif1 DNA helicases in Saccharomyces cerevisiae.RecQ helicases: suppressors of tumorigenesis and premature aging.Absence of BLM leads to accumulation of chromosomal DNA breaks during both unperturbed and disrupted S phasesDefective p53 engagement after the induction of DNA damage in cells deficient in topoisomerase 3betaMechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stabilityThe BLM dissolvasome in DNA replication and repair.Synthesis and dissolution of hemicatenanes by type IA DNA topoisomerases.Possible anti-recombinogenic role of Bloom's syndrome helicase in double-strand break processingBloom's Syndrome: Clinical Spectrum, Molecular Pathogenesis, and Cancer Predisposition.RecQ helicases; at the crossroad of genome replication, repair, and recombination.The DNA binding properties of the Escherichia coli RecQ helicase.Osteosarcoma: Molecular Pathogenesis and iPSC Modeling.Top3 processes recombination intermediates and modulates checkpoint activity after DNA damage.The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres.Essential functions of C terminus of Drosophila Topoisomerase IIIα in double holliday junction dissolutionThe genetic consequences of ablating helicase activity and the Top3 interaction domain of Sgs1.RecQ helicase stimulates both DNA catenation and changes in DNA topology by topoisomerase III.The topoisomerase 3α zinc-finger domain T1 of Arabidopsis thaliana is required for targeting the enzyme activity to Holliday junction-like DNA repair intermediates
P2860
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P2860
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
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2002 nî lūn-bûn
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2002 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
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2002 թվականի նոյեմբերին հրատարակված գիտական հոդված
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2002年の論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年論文
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2002年论文
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name
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@ast
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@en
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@nl
type
label
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@ast
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@en
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@nl
prefLabel
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@ast
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@en
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@nl
P2860
P356
P1476
The Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalpha
@en
P2093
Ian D Hickson
Leonard Wu
P2860
P304
P356
10.1093/NAR/GKF611
P407
P577
2002-11-01T00:00:00Z