DNA T OPOISOMERASES : Structure, Function, and Mechanism
about
A DNA topoisomerase IB in Thaumarchaeota testifies for the presence of this enzyme in the last common ancestor of Archaea and EucaryaCellular roles of dna topoisomerases: a molecular perspectiveBiochemical characterization of human tyrosyl-DNA phosphodiesterase 2 (TDP2/TTRAP): a Mg(2+)/Mn(2+)-dependent phosphodiesterase specific for the repair of topoisomerase cleavage complexesThe role of lysine 532 in the catalytic mechanism of human topoisomerase ISubstrate specificity of tyrosyl-DNA phosphodiesterase I (Tdp1)Inhibition of topoisomerase I cleavage activity by thiol-reactive compounds: importance of vicinal cysteines 504 and 505TDP2/TTRAP is the major 5'-tyrosyl DNA phosphodiesterase activity in vertebrate cells and is critical for cellular resistance to topoisomerase II-induced DNA damageDNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNAHuman topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1Amygdalin inhibits genes related to cell cycle in SNU-C4 human colon cancer cellsA human 5'-tyrosyl DNA phosphodiesterase that repairs topoisomerase-mediated DNA damageFunctional interaction between the Bloom's syndrome helicase and the RAD51 paralog, RAD51L3 (RAD51D)Dual localization of human DNA topoisomerase IIIalpha to mitochondria and nucleusThe Bloom's syndrome helicase stimulates the activity of human topoisomerase IIIalphaStructure of the N-terminal fragment of topoisomerase V reveals a new family of topoisomerases.Crystal structures of Escherichia coli topoisomerase IV ParE subunit (24 and 43 kilodaltons): a single residue dictates differences in novobiocin potency against topoisomerase IV and DNA gyrase(-)-Epigallocatechin gallate, a major constituent of green tea, poisons human type II topoisomerasesBioflavonoids as poisons of human topoisomerase II alpha and II betaDietary polyphenols as topoisomerase II poisons: B ring and C ring substituents determine the mechanism of enzyme-mediated DNA cleavage enhancementRoles of Werner syndrome protein in protection of genome integrityOptimal function of the DNA repair enzyme TDP1 requires its phosphorylation by ATM and/or DNA-PKSR proteins in vertical integration of gene expression from transcription to RNA processing to translationGlutamate racemase from Mycobacterium tuberculosis inhibits DNA gyrase by affecting its DNA-bindingMms22p protects Saccharomyces cerevisiae from DNA damage induced by topoisomerase IIThe role of the Zn(II) binding domain in the mechanism of E. coli DNA topoisomerase IFunctional interaction of reverse gyrase with single-strand binding protein of the archaeon SulfolobusInhibition of archaeal growth and DNA topoisomerase VI activities by the Hsp90 inhibitor radicicolGenomic transcriptional response to loss of chromosomal supercoiling in Escherichia coliA monoclonal antibody that inhibits mycobacterial DNA gyrase by a novel mechanism.Atomic force microscopy shows that vaccinia topoisomerase IB generates filaments on DNA in a cooperative fashion.Rotation of DNA around intact strand in human topoisomerase I implies distinct mechanisms for positive and negative supercoil relaxationGenomes are covered with ubiquitous 11 bp periodic patterns, the "class A flexible patterns".Bacillus cereus DNA topoisomerase I and IIIalpha: purification, characterization and complementation of Escherichia coli TopoIII activity.Differential induction of Leishmania donovani bi-subunit topoisomerase I-DNA cleavage complex by selected flavones and camptothecin: activity of flavones against camptothecin-resistant topoisomerase I.Mechanisms of Nuclear Export in Cancer and Resistance to ChemotherapyIncorporation of omics analyses into artificial gravity research for space exploration countermeasure developmentProtein design: toward functional metalloenzymesDrugging topoisomerases: lessons and challengesRecent progress on C-4-modified podophyllotoxin analogs as potent antitumor agentsBreakage-reunion domain of Streptococcus pneumoniae topoisomerase IV: crystal structure of a gram-positive quinolone target
P2860
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P2860
DNA T OPOISOMERASES : Structure, Function, and Mechanism
description
2001 nî lūn-bûn
@nan
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2001年の論文
@ja
2001年論文
@yue
2001年論文
@zh-hant
2001年論文
@zh-hk
2001年論文
@zh-mo
2001年論文
@zh-tw
2001年论文
@wuu
name
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@ast
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@en
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@en-gb
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@nl
type
label
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@ast
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@en
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@en-gb
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@nl
altLabel
DNA topoisomerases: structure, function, and mechanism
@en
prefLabel
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@ast
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@en
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@en-gb
DNA T OPOISOMERASES : Structure, Function, and Mechanism
@nl
P3181
P1476
DNA topoisomerases: structure, function, and mechanism
@en
P2093
James J. Champoux
P304
P3181
P356
10.1146/ANNUREV.BIOCHEM.70.1.369
P407
P577
2001-06-01T00:00:00Z