Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
about
The emerging importance of group II PAKsThe role of p21-activated kinases in hepatocellular carcinoma metastasisCrystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKsPAK thread from amoeba to mammalsInteraction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish developmentP21-activated kinase 5 plays essential roles in the proliferation and tumorigenicity of human hepatocellular carcinoma.Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.Depletion of cytotoxic T-cells does not protect NUP98-HOXD13 mice from myelodysplastic syndrome but reveals a modest tumor immunosurveillance effect.p21-activated kinase 4 regulates ovarian cancer cell proliferation, migration, and invasion and contributes to poor prognosis in patientsA role for p21-activated kinase 7 in the development of gastric cancer.The overexpression of P21-activated kinase 5 (PAK5) promotes paclitaxel-chemoresistance of epithelial ovarian cancer.P21-activated kinase 7 mediates cisplatin-resistance of esophageal squamous carcinoma cells with Aurora-A overexpression.p21-Activated kinase 5 affects cisplatin-induced apoptosis and proliferation in hepatocellular carcinoma cells.Efficient inhibition of human glioma development by RNA interference-mediated silencing of PAK5GATA1 induces epithelial-mesenchymal transition in breast cancer cells through PAK5 oncogenic signaling.CRNDE affects the malignant biological characteristics of human glioma stem cells by negatively regulating miR-186.Retinal degeneration modulates intracellular localization of CDC42 in photoreceptorsTumor Suppressive Function of p21-activated Kinase 6 in Hepatocellular Carcinomap21 activated kinase 5 activates Raf-1 and targets it to mitochondriaA tale of two Paks.PAK signaling in oncogenesis.High-level expression of P21-Cdc/Rac-activated kinase 7 is closely related to metastatic potential and poor prognosis of colon carcinoma.An oncogenic kinase: putting PAK5 forward.N-terminal interaction domain implicates PAK4 in translational regulation and reveals novel cellular localization signals.Combined inhibition of PAK7, MAP3K7 and CK2alpha kinases inhibits the growth of MiaPaCa2 pancreatic cancer cell xenografts.High expression of P21-activated kinase 5 protein is associated with poor survival in gastric cancer.PAK family kinases: Physiological roles and regulation.PAK5 Induces EMT and Promotes Cell Migration and Invasion by Activating the PI3K/AKT Pathway in Ovarian Cancer
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P2860
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
description
2006 nî lūn-bûn
@nan
2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年論文
@yue
2006年論文
@zh-hant
2006年論文
@zh-hk
2006年論文
@zh-mo
2006年論文
@zh-tw
2006年论文
@wuu
name
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@ast
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@en
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@nl
type
label
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@ast
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@en
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@nl
prefLabel
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@ast
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@en
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@nl
P2860
P3181
P1476
Nucleocytoplasmic shuttling of Pak5 regulates its antiapoptotic properties
@en
P2093
Sophie Cotteret
P2860
P304
P3181
P356
10.1128/MCB.26.8.3215-3230.2006
P407
P577
2006-04-01T00:00:00Z