Proteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infection - Wikidata - awgldk - TriplyDB

Proteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infection

Proteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infection

http://www.wikidata.org/entity/Q24544232

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The cell biology of HIV-1 and other retroviruses TRIM5α associates with proteasomal subunits in cells while in complex with HIV-1 virions TRIM5α and Species Tropism of HIV/SIV p62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha.Cell-to-cell transmission of retroviruses: Innate immunity and interferon-induced restriction factors TRIM family proteins and their emerging roles in innate immunity Restriction of retroviral replication by APOBEC3G/F and TRIM5alpha Independent evolution of an antiviral TRIMCyp in rhesus macaques Evolution of foamy viruses: the most ancient of all retroviruses Coupling viruses to dynein and kinesin-1 HIV restriction in quiescent CD4⁺ T cells HIV-1 reverse transcription Conformational Adaptation of Asian Macaque TRIMCyp Directs Lineage Specific Antiviral Activity Novel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid Protein Lentiviral Vpx accessory factor targets VprBP/DCAF1 substrate adaptor for cullin 4 E3 ubiquitin ligase to enable macrophage infection Rhesus TRIM5α disrupts the HIV-1 capsid at the inter-hexamer interfaces Fates of retroviral core components during unrestricted and TRIM5-restricted infection Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration Intrinsic cellular defenses against human immunodeficiency viruses Evolution of the antiretroviral restriction factor TRIMCyp in Old World primates Primate TRIM5 proteins form hexagonal nets on HIV-1 capsids.SIV replication in human cells Hexagonal assembly of a restricting TRIM5alpha protein The structural biology of HIV assembly.Recruitment and dynamics of proteasome association with rhTRIM5α cytoplasmic complexes during HIV-1 infection.HIV-1 uncoating is facilitated by dynein and kinesin 1 Primate lentiviral Vpx commandeers DDB1 to counteract a macrophage restriction.Proteasomal degradation of TRIM5alpha during retrovirus restriction Functional evidence for the involvement of microtubules and dynein motor complexes in TRIM5α-mediated restriction of retroviruses.Novel approaches to inhibiting HIV-1 replication.Stabilized human TRIM5α protects human T cells from HIV-1 infection.Role of human immunodeficiency virus type 1 integrase in uncoating of the viral core.The specificity of TRIM5 alpha-mediated restriction is influenced by its coiled-coil domain.A single amino acid of human immunodeficiency virus type 2 capsid protein affects conformation of two external loops and viral sensitivity to TRIM5α.TRIM5alpha disrupts the structure of assembled HIV-1 capsid complexes in vitro.Innate immune recognition and activation during HIV infection.A TRIM5alpha exon 2 polymorphism is associated with protection from HIV-1 infection in the Pumwani sex worker cohort.Direct visualization of HIV-1 with correlative live-cell microscopy and cryo-electron tomography.Immunogenetic Management Software: a new tool for visualization and analysis of complex immunogenetic datasets.Characterization of the alpha interferon-induced postentry block to HIV-1 infection in primary human macrophages and T cells.

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P2860

Proteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infection

http://www.wikidata.org/entity/Q24544232

description

2006 nî lūn-bûn

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2006 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2006 թվականի մայիսին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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Proteasome inhibitors uncouple ...... se transcription and infection

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Proteasome inhibitors uncouple ...... se transcription and infection

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Proceedings of the National Academy of Sciences of the United States of America

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Proteasome inhibitors uncouple ...... se transcription and infection

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Ajith M Joseph

http://www.w3.org/2001/XMLSchema#string

Edward M Campbell

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Thomas J Hope

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Xiaolu Wu

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P2860

The tripartite motif family identifies cell compartments.

BTBD1 and BTBD2 colocalize to cytoplasmic bodies with the RBCC/tripartite motif protein, TRIM5delta

TRIM family proteins: retroviral restriction and antiviral defence

The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities

Retrovirus resistance factors Ref1 and Lv1 are species-specific variants of TRIM5alpha

The cytoplasmic body component TRIM5alpha restricts HIV-1 infection in Old World monkeys

Positive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domain

Cyclophilin A retrotransposition into TRIM5 explains owl monkey resistance to HIV-1

Proteasome inhibitors: valuable new tools for cell biologists

Species-specific, postentry barriers to primate immunodeficiency virus infection.

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7465-70

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103

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