The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities
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Evidence for restriction of ancient primate gammaretroviruses by APOBEC3 but not TRIM5alpha proteinsTRIM5alpha selectively binds a restriction-sensitive retroviral capsidDisruption of human TRIM5alpha antiviral activity by nonhuman primate orthologuesp62/sequestosome-1 associates with and sustains the expression of retroviral restriction factor TRIM5alpha.TRIM E3 ligases interfere with early and late stages of the retroviral life cycleSystematic analysis of dimeric E3-RING interactions reveals increased combinatorial complexity in human ubiquitination networksTRIM family proteins: retroviral restriction and antiviral defenceCyclophilin A is required for TRIM5{alpha}-mediated resistance to HIV-1 in Old World monkey cellsProteasome inhibitors uncouple rhesus TRIM5alpha restriction of HIV-1 reverse transcription and infectionSpecific recognition and accelerated uncoating of retroviral capsids by the TRIM5alpha restriction factorFunctional replacement of the RING, B-box 2, and coiled-coil domains of tripartite motif 5alpha (TRIM5alpha) by heterologous TRIM domainsIn defense of the cell: TRIM5alpha interception of mammalian retrovirusesRestriction of retroviral replication by APOBEC3G/F and TRIM5alphaIndependent evolution of an antiviral TRIMCyp in rhesus macaquesAll three variable regions of the TRIM5alpha B30.2 domain can contribute to the specificity of retrovirus restrictionIntracellular immunity to HIV-1: newly defined retroviral battles inside infected cells.Nonhuman primate models for HIV/AIDS vaccine developmentArsenic Trioxide Inhibits Hepatitis C Virus RNA Replication through Modulation of the Glutathione Redox System and Oxidative StressNovel Escape Mutants Suggest an Extensive TRIM5α Binding Site Spanning the Entire Outer Surface of the Murine Leukemia Virus Capsid ProteinDiverse HIV viruses are targeted by a conformationally dynamic antiviralTRIM5alpha Modulates Immunodeficiency Virus Control in Rhesus MonkeysFates of retroviral core components during unrestricted and TRIM5-restricted infectionMG53 regulates membrane budding and exocytosis in muscle cells.Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to IntegrationApparent effect of rabbit endogenous lentivirus type K acquisition on retrovirus restriction by lagomorph Trim5αsTwo-stepping through time: mammals and virusesIdentification of a receptor for an extinct virusEvolution of the antiretroviral restriction factor TRIMCyp in Old World primatesPositive selection of primate TRIM5alpha identifies a critical species-specific retroviral restriction domainA rare null allele potentially encoding a dominant-negative TRIM5alpha protein in Baka pygmiesSolid-state NMR studies of HIV-1 capsid protein assemblies.SIV replication in human cells9-Aminoacridine inhibition of HIV-1 Tat dependent transcription.TRIM5 alpha cytoplasmic bodies are highly dynamic structures.A specific region of 37 amino acid residues in the SPRY (B30.2) domain of African green monkey TRIM5alpha determines species-specific restriction of simian immunodeficiency virus SIVmac infection.HIV-1 uses dynamic capsid pores to import nucleotides and fuel encapsidated DNA synthesisDiscordant evolution of the adjacent antiretroviral genes TRIM22 and TRIM5 in mammals.TRIM5 alpha drives SIVsmm evolution in rhesus macaques.The DNA repair genes XPB and XPD defend cells from retroviral infectionInterfering residues narrow the spectrum of MLV restriction by human TRIM5alpha.
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P2860
The human and African green monkey TRIM5alpha genes encode Ref1 and Lv1 retroviral restriction factor activities
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2004 nî lūn-bûn
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2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
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2004 թվականի հուլիսին հրատարակված գիտական հոդված
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2004年の論文
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年学术文章
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2004年學術文章
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name
The human and African green mo ...... restriction factor activities
@ast
The human and African green mo ...... restriction factor activities
@en
The human and African green mo ...... restriction factor activities
@nl
type
label
The human and African green mo ...... restriction factor activities
@ast
The human and African green mo ...... restriction factor activities
@en
The human and African green mo ...... restriction factor activities
@nl
prefLabel
The human and African green mo ...... restriction factor activities
@ast
The human and African green mo ...... restriction factor activities
@en
The human and African green mo ...... restriction factor activities
@nl
P2093
P2860
P356
P1476
The human and African green mo ...... restriction factor activities
@en
P2093
Greg J Towers
Laura M J Ylinen
Zuzana Keckesova
P2860
P304
P356
10.1073/PNAS.0402474101
P407
P577
2004-07-20T00:00:00Z