Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome - Wikidata - awgldk - TriplyDB

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

http://www.wikidata.org/entity/Q24548457

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LRP1 functions as an atheroprotective integrator of TGFbeta and PDFG signals in the vascular wall: implications for Marfan syndrome ADAMTS10 protein interacts with fibrillin-1 and promotes its deposition in extracellular matrix of cultured fibroblasts.Fibrillin-1 and -2 differentially modulate endogenous TGF-β and BMP bioavailability during bone formation Klf15 deficiency is a molecular link between heart failure and aortic aneurysm formation Essential role for fibrillin-2 in zebrafish notochord and vascular morphogenesis Aortic Aneurysm: Etiopathogenesis and Clinicopathologic Correlations Marfan syndrome: current perspectives Mitral valve disease--morphology and mechanisms.Vascular complications in autosomal dominant polycystic kidney disease Genetic and functional linkage between ADAMTS superfamily proteins and fibrillin-1: a novel mechanism influencing microfibril assembly and function Medical treatment of aortic aneurysms in Marfan syndrome and other heritable conditions Epidemiology and pathophysiology of mitral valve prolapse: new insights into disease progression, genetics, and molecular basis Defining the extracellular matrix using proteomics Aneurysms of the ascending aorta Translating ocular biomechanics into clinical practice: current state and future prospects.Educational paper. Connective tissue disorders with vascular involvement: from gene to therapy Fibrocalcific aortic valve disease: opportunity to understand disease mechanisms using mouse models Corneal stroma microfibrils Matrix control of transforming growth factor-β function Genetics of valvular heart disease Tenascin-C in development and disease of blood vessels Abnormal Activation of BMP Signaling Causes Myopathy in Fbn2 Null Mice Reduction of NADPH-oxidase activity ameliorates the cardiovascular phenotype in a mouse model of Williams-Beuren Syndrome Microenvironmental regulation by fibrillin-1 Repurposing of approved cardiovascular drugs Modifier genes and their effect on Duchenne muscular dystrophy ADAMTS proteins as modulators of microfibril formation and function Targeting of bone morphogenetic protein growth factor complexes to fibrillin Rare variants in FBN1 and FBN2 are associated with severe adolescent idiopathic scoliosis Marfan syndrome: An eyesight of syndrome Angiotensin II blockade and aortic-root dilation in Marfan's syndrome LRP1 regulates architecture of the vascular wall by controlling PDGFRbeta-dependent phosphatidylinositol 3-kinase activation Ang II enhances noradrenaline release from sympathetic nerve endings thus contributing to the up-regulation of metalloprotease-2 in aortic dissection patients' aorta wall No beneficial effect of general and specific anti-inflammatory therapies on aortic dilatation in Marfan mice Losartan Treatment Protects Retinal Ganglion Cells and Alters Scleral Remodeling in Experimental Glaucoma Decorin-mediated regulation of fibrillin-1 in the kidney involves the insulin-like growth factor-I receptor and Mammalian target of rapamycin A thrombospondin-1 antagonist of transforming growth factor-beta activation blocks cardiomyopathy in rats with diabetes and elevated angiotensin II Microfibril-associated glycoprotein 2 (MAGP2) loss of function has pleiotropic effects in vivo Adamtsl2 deletion results in bronchial fibrillin microfibril accumulation and bronchial epithelial dysplasia--a novel mouse model providing insights into geleophysic dysplasia TGFB1 genetic polymorphisms and coronary heart disease risk: a meta-analysis

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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

http://www.wikidata.org/entity/Q24548457

description

2006 nî lūn-bûn

@nan

2006 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2006 թվականի ապրիլին հրատարակված գիտական հոդված

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2006年の論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年論文

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2006年论文

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name

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@ast

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@en

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@nl

type

label

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@ast

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@en

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@nl

prefLabel

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@ast

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@en

Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

@nl

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Losartan, an AT1 antagonist, prevents aortic aneurysm in a mouse model of Marfan syndrome

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Carla Calvi

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Daniel B Rifkin

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Daniel P Judge

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David L Huso

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Djahida Bedja

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Enid R Neptune

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Erin C Klein

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Francesco Ramirez

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Guosheng Liu

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Harry C Dietz

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P2860

Evidence for a critical contribution of haploinsufficiency in the complex pathogenesis of Marfan syndrome

Purification and partial characterization of fibrillin, a cysteine-rich structural component of connective tissue microfibrils

Latent transforming growth factor beta-binding protein 1 interacts with fibrillin and is a microfibril-associated protein

TGF-beta signalling from cell membrane to nucleus through SMAD proteins

A syndrome of altered cardiovascular, craniofacial, neurocognitive and skeletal development caused by mutations in TGFBR1 or TGFBR2

Angiotensin II blockade reverses myocardial fibrosis in a transgenic mouse model of human hypertrophic cardiomyopathy

Antagonism of AT2 receptors augments angiotensin II-induced abdominal aortic aneurysms and atherosclerosis

Dysregulation of TGF-beta activation contributes to pathogenesis in Marfan syndrome

Angiotensin receptor regulates cardiac hypertrophy and transforming growth factor-beta 1 expression.

Pulmonary artery root dilatation in Marfan syndrome: quantitative assessment of an unknown criterion

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