Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1 - Wikidata - awgldk - TriplyDB

Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

http://www.wikidata.org/entity/Q24555123

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BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity RECQ1 helicase interacts with human mismatch repair factors that regulate genetic recombination Stimulation of flap endonuclease-1 by the Bloom's syndrome protein Physical and functional interactions between Werner syndrome helicase and mismatch-repair initiation factors Physical and functional interaction between the Bloom's syndrome gene product and the largest subunit of chromatin assembly factor 1 Analysis of the unwinding activity of the dimeric RECQ1 helicase in the presence of human replication protein A ATM-mediated stabilization of hMutL DNA mismatch repair proteins augments p53 activation during DNA damage Human pyruvate kinase M2: a multifunctional protein The Bloom's syndrome helicase (BLM) interacts physically and functionally with p12, the smallest subunit of human DNA polymerase delta A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome Structure of the MutLα C-terminal domain reveals how Mlh1 contributes to Pms1 endonuclease site Genetic analysis of mlh3 mutations reveals interactions between crossover promoting factors during meiosis in baker's yeast.Characterization of the interactome of the human MutL homologues MLH1, PMS1, and PMS2 RecQ helicases: caretakers of the genome Unwinding protein complexes in ALTernative telomere maintenance.Effects of mutations in SGS1 and in genes functionally related to SGS1 on inverted repeat-stimulated spontaneous unequal sister-chromatid exchange in yeast Mechanisms of recombination between diverged sequences in wild-type and BLM-deficient mouse and human cells.Exploring the link between MORF4L1 and risk of breast cancer.hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair.Systematic mutagenesis of the Saccharomyces cerevisiae MLH1 gene reveals distinct roles for Mlh1p in meiotic crossing over and in vegetative and meiotic mismatch repair Examination of the roles of Sgs1 and Srs2 helicases in the enforcement of recombination fidelity in Saccharomyces cerevisiae Analysis of conditional mutations in the Saccharomyces cerevisiae MLH1 gene in mismatch repair and in meiotic crossing over.MLH1 mutations differentially affect meiotic functions in Saccharomyces cerevisiae Role of mismatch repair in the fidelity of RAD51- and RAD59-dependent recombination in Saccharomyces cerevisiae.Genes and pathways driving glioblastomas in humans and murine disease models.RecQ helicases: suppressors of tumorigenesis and premature aging.DNA mismatch repair proteins are required for efficient herpes simplex virus 1 replication Structure and function of RecQ DNA helicases.Structure of the human MLH1 N-terminus: implications for predisposition to Lynch syndrome Multiple functions of Drosophila BLM helicase in maintenance of genome stability.BLM ortholog, Sgs1, prevents aberrant crossing-over by suppressing formation of multichromatid joint molecules.Critical interaction domains between bloom syndrome protein and RAD51 Accumulation and Phosphorylation of RecQ-Mediated Genome Instability Protein 1 (RMI1) at Serine 284 and Serine 292 during Mitosis.Roles for mismatch repair family proteins in promoting meiotic crossing over.Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability Sequence divergence impedes crossover more than noncrossover events during mitotic gap repair in yeast.The BLM dissolvasome in DNA replication and repair.Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair.Genomic instability resulting from Blm deficiency compromises development, maintenance, and function of the B cell lineage.Primary immunodeficiencies associated with DNA-repair disorders.

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Direct association of Bloom's syndrome gene product with the human mismatch repair protein MLH1

http://www.wikidata.org/entity/Q24555123

description

2001 nî lūn-bûn

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2001 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2001年の論文

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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Nucleic Acids Research

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Direct association of Bloom's ...... n mismatch repair protein MLH1

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C Perrera

http://www.w3.org/2001/XMLSchema#string

G H Ryu

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G Marra

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G Pedrazzi

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H Blaser

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I D Hickson

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I Stagljar

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J Jiricny

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P Kuster

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S L Davies

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P2860

Cloning of two new human helicase genes of the RecQ family: biological significance of multiple species in higher eukaryotes

Mutations in RECQL4 cause a subset of cases of Rothmund-Thomson syndrome

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

The Bloom's syndrome gene product is a 3'-5' DNA helicase

DNA polymerase delta is required for human mismatch repair in vitro

The Bloom's syndrome gene product is homologous to RecQ helicases

Bloom's and Werner's syndrome genes suppress hyperrecombination in yeast sgs1 mutant: implication for genomic instability in human diseases

The evolutionarily conserved zinc finger motif in the largest subunit of human replication protein A is required for DNA replication and mismatch repair but not for nucleotide excision repair

Cloning and characterization of RECQL, a potential human homologue of the Escherichia coli DNA helicase RecQ

The interacting domains of three MutL heterodimers in man: hMLH1 interacts with 36 homologous amino acid residues within hMLH3, hPMS1 and hPMS2

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4378-4386

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10.1093/NAR/29.21.4378

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21

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29

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Raimundo Freire

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274442812

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