A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint - Wikidata - awgldk - TriplyDB

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

http://www.wikidata.org/entity/Q24558787

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The BRCA1/2 pathway prevents hematologic cancers in addition to breast and ovarian cancers BRCA1 affects global DNA methylation through regulation of DNMT1 BRCA1 participates in DNA decatenation BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution The BRCA1 Breast Cancer Suppressor: Regulation of Transport, Dynamics, and Function at Multiple Subcellular Locations Transcriptional control of mitosis: deregulation and cancer The Polycomb group protein EZH2 impairs DNA repair in breast epithelial cells BRCA1 targets G2/M cell cycle proteins for ubiquitination and proteasomal degradation A general mechanism for transcription regulation by Oct1 and Oct4 in response to genotoxic and oxidative stress Transcriptional regulation prediction of antiestrogen resistance in breast cancer based on RNA polymerase II binding data.Breast tumor copy number aberration phenotypes and genomic instability Murine Wee1 plays a critical role in cell cycle regulation and pre-implantation stages of embryonic development.RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation.Patterns of cell cycle checkpoint deregulation associated with intrinsic molecular subtypes of human breast cancer cells.Dynamic regulation of Oct1 during mitosis by phosphorylation and ubiquitination.Identification of gene fusion transcripts by transcriptome sequencing in BRCA1-mutated breast cancers and cell lines The POU transcription factor Oct-1 represses virus-induced interferon A gene expression.Transcriptional autoregulation by BRCA1.Impact of α-targeted radiation therapy on gene expression in a pre-clinical model for disseminated peritoneal disease when combined with paclitaxel.SIRT1 deacetylates TopBP1 and modulates intra-S-phase checkpoint and DNA replication origin firing The breast cancer susceptibility genes (BRCA) in breast and ovarian cancers.Heregulin-dependent delay in mitotic progression requires HER4 and BRCA1.Hyperplasia and spontaneous tumor development in the gynecologic system in mice lacking the BRCA1-Delta11 isoform.Hepatic Sirt1 deficiency in mice impairs mTorc2/Akt signaling and results in hyperglycemia, oxidative damage, and insulin resistance.Topoisomerase IIα in chromosome instability and personalized cancer therapy.DNA damage response and spindle assembly checkpoint function throughout the cell cycle to ensure genomic integrity.Positional analyses of BRCA1-dependent expression in Saccharomyces cerevisiae.Suppressors of spindle checkpoint defect (such) mutants identify new mdf-1/MAD1 interactors in Caenorhabditis elegans.Tumour suppressor genes in chemotherapeutic drug response.Progression of chronic liver inflammation and fibrosis driven by activation of c-JUN signaling in Sirt6 mutant mice Impact of intertumoral heterogeneity on predicting chemotherapy response of BRCA1-deficient mammary tumors.Genetic predictors of taxane-induced neurotoxicity in a SWOG phase III intergroup adjuvant breast cancer treatment trial (S0221).Mouse models of BRCA1 and BRCA2 deficiency: past lessons, current understanding and future prospects.Age-associated increase in aneuploidy and changes in gene expression in mouse eggs Aberrant expression of LMO4 induces centrosome amplification and mitotic spindle abnormalities in breast cancer cells.The Oct1 transcription factor and epithelial malignancies: Old protein learns new tricks Regulation of Oct1/Pou2f1 transcription activity by O-GlcNAcylation.BRCA1 in the DNA damage response and at telomeres Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis.BRCA1, hormone, and tissue-specific tumor suppression

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P2860

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

http://www.wikidata.org/entity/Q24558787

description

2004 nî lūn-bûn

@nan

2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված

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2004年の論文

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2004年論文

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2004年論文

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2004年論文

@zh-hk

2004年論文

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2004年論文

@zh-tw

2004年论文

@wuu

name

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@ast

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@en

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@nl

type

label

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@ast

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@en

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@nl

prefLabel

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@ast

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@en

A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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A requirement for breast-cancer-associated gene 1 (BRCA1) in the spindle checkpoint

@en

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Chu-Xia Deng

http://www.w3.org/2001/XMLSchema#string

Hongtao Yu

http://www.w3.org/2001/XMLSchema#string

Rui-Hong Wang

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P2860

Roles of BRCA1 and its interacting proteins

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

Checkpoint protein BubR1 acts synergistically with Mad2 to inhibit anaphase-promoting complex

Checkpoint inhibition of the APC/C in HeLa cells is mediated by a complex of BUBR1, BUB3, CDC20, and MAD2

BRCA1 regulates p53-dependent gene expression

WAF1, a potential mediator of p53 tumor suppression

Regulation of APC-Cdc20 by the spindle checkpoint

Cancer susceptibility and the functions of BRCA1 and BRCA2

Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

MAD2 haplo-insufficiency causes premature anaphase and chromosome instability in mammalian cells

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scholarly article

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1293201

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10.1073/PNAS.0407585101

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15563594

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535394

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