The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors
about
Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesisA potential role for tetranectin in mineralization during osteogenesisCharacterization of SMOC-2, a modular extracellular calcium-binding proteinHPP1: a transmembrane protein-encoding gene commonly methylated in colorectal polyps and cancersImpaired wound healing in mice deficient in a matricellular protein SPARC (osteonectin, BM-40)Platelet-derived growth factors (PDGFs) in glomerular and tubulointerstitial fibrosisMatrikine and matricellular regulators of EGF receptor signaling on cancer cell migration and invasionSIBLINGs and SPARC families: their emerging roles in pancreatic cancerSPARC, a matricellular glycoprotein with important biological functionsIdentification and characterization of a novel follistatin-like protein as a binding protein for the TGF-beta familyInteraction of platelet-derived growth factor with thrombospondin 1TMEFF2 is a PDGF-AA binding protein with methylation-associated gene silencing in multiple cancer types including gliomaRole of platelet-derived growth factors in physiology and medicineCharacterization of Smoc-1 uncovers two transcript variants showing differential tissue and age specific expression in Bubalus bubalis.An integrative approach to characterize disease-specific pathways and their coordination: a case study in cancer.Modulatory proteins and processes in alliance with immune cells, mediators, and extracellular proteins in renal interstitial fibrosis.Lack of host SPARC enhances vascular function and tumor spread in an orthotopic murine model of pancreatic carcinoma.The role of MMP-9 in the anti-angiogenic effect of secreted protein acidic and rich in cysteine.Increased expression of osteonectin/SPARC mRNA and protein in age-related human cataracts and spatial expression in the normal human lens.miR-29 suppression of osteonectin in osteoblasts: regulation during differentiation and by canonical Wnt signalingAttenuation of fibrosis in vitro and in vivo with SPARC siRNARelationship and prognostic significance of SPARC and VEGF protein expression in colon cancer.The extracellular matrix can regulate vascular cell migration, proliferation, and survival: relationships to vascular disease.Secreted protein acidic and rich in cysteine is a matrix scavenger chaperone.PTEN augments SPARC suppression of proliferation and inhibits SPARC-induced migration by suppressing SHC-RAF-ERK and AKT signaling.High expression of genes for calcification-regulating proteins in human atherosclerotic plaques.Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation.Osteonectin/SPARC secreted by RPE and localized to the outer plexiform layer of the monkey retina.Novel role for matricellular proteins in the regulation of islet β cell survival: the effect of SPARC on survival, proliferation, and signaling.Expression of SPARC during development of the chicken chorioallantoic membrane: evidence for regulated proteolysis in vivo.The novel SPARC family member SMOC-2 potentiates angiogenic growth factor activity.SPARC fusion protein induces cellular adhesive signaling.SPARC expression in CML is associated to imatinib treatment and to inhibition of leukemia cell proliferationThe expression of SPARC in human intracranial aneurysms and its relationship with MMP-2/-9.Proteolytic events of wound-healing--coordinated interactions among matrix metalloproteinases (MMPs), integrins, and extracellular matrix molecules.Association between SPARC mRNA expression, prognosis and response to neoadjuvant chemotherapy in early breast cancer: a pooled in-silico analysisTranscriptome analysis of the desert locust central nervous system: production and annotation of a Schistocerca gregaria EST databaseDevelopmental expression of Smoc1 and Smoc2 suggests potential roles in fetal gonad and reproductive tract differentiation.Anti-cancer role of SPARC, an inhibitor of adipogenesismiR-29a/b enhances cell migration and invasion in nasopharyngeal carcinoma progression by regulating SPARC and COL3A1 gene expression.
P2860
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P2860
The extracellular glycoprotein SPARC interacts with platelet-derived growth factor (PDGF)-AB and -BB and inhibits the binding of PDGF to its receptors
description
1992 nî lūn-bûn
@nan
1992 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1992 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1992年の論文
@ja
1992年学术文章
@wuu
1992年学术文章
@zh-cn
1992年学术文章
@zh-hans
1992年学术文章
@zh-my
1992年学术文章
@zh-sg
1992年學術文章
@yue
name
The extracellular glycoprotein ...... nding of PDGF to its receptors
@ast
The extracellular glycoprotein ...... nding of PDGF to its receptors
@en
The extracellular glycoprotein ...... nding of PDGF to its receptors
@nl
type
label
The extracellular glycoprotein ...... nding of PDGF to its receptors
@ast
The extracellular glycoprotein ...... nding of PDGF to its receptors
@en
The extracellular glycoprotein ...... nding of PDGF to its receptors
@nl
prefLabel
The extracellular glycoprotein ...... nding of PDGF to its receptors
@ast
The extracellular glycoprotein ...... nding of PDGF to its receptors
@en
The extracellular glycoprotein ...... nding of PDGF to its receptors
@nl
P2093
P2860
P356
P1476
The extracellular glycoprotein ...... nding of PDGF to its receptors
@en
P2093
E W Raines
M L Iruela-Arispe
P2860
P304
P356
10.1073/PNAS.89.4.1281
P407
P577
1992-02-15T00:00:00Z