Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap
about
Premature senescence involving p53 and p16 is activated in response to constitutive MEK/MAPK mitogenic signalingTransforming growth factor-beta-stimulated clone-22 is a member of a family of leucine zipper proteins that can homo- and heterodimerize and has transcriptional repressor activityPDZ-GEF1, a guanine nucleotide exchange factor specific for Rap1 and Rap2The RAP1 guanine nucleotide exchange factor Epac2 couples cyclic AMP and Ras signals at the plasma membraneGenetic and functional characterization of putative Ras/Raf interaction inhibitors in C. elegans and mammalian cellsIdentification and characterization of a novel protein interacting with Ral-binding protein 1, a putative effector protein of RalProtein binding and signaling properties of RIN1 suggest a unique effector functionRabaptin4, a novel effector of the small GTPase rab4a, is recruited to perinuclear recycling vesiclesInsulin regulates the dynamic balance between Ras and Rap1 signaling by coordinating the assembly states of the Grb2-SOS and CrkII-C3G complexes.PDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanismR-Ras promotes focal adhesion formation through focal adhesion kinase and p130(Cas) by a novel mechanism that differs from integrins.Ral-GTPases mediate a distinct downstream signaling pathway from Ras that facilitates cellular transformationActivation of phosphoinositide 3-kinase by interaction with Ras and by point mutationIdentification and characterization of Ral-binding protein 1, a potential downstream target of Ral GTPasesThe Ras target AF-6 is a substrate of the fam deubiquitinating enzymeA rapid, membrane-dependent pathway directs furrow formation through RalA in the early Drosophila embryo.Identification of a novel RalGDS-related protein as a candidate effector for Ras and Rap1Multiple interactions between receptor protein-tyrosine phosphatase (RPTP) alpha and membrane-distal protein-tyrosine phosphatase domains of various RPTPsCalmodulin binds RalA and RalB and is required for the thrombin-induced activation of Ral in human plateletsSpecific association of nitric oxide synthase-2 with Rac isoforms in activated murine macrophagesInvolvement of phosphatidylinositol 3-kinase, but not RalGDS, in TC21/R-Ras2-mediated transformationActivation of Ras/Erk pathway by a novel MET-interacting protein RanBPMIdentification and characterization of a calmodulin-binding domain in Ral-A, a Ras-related GTP-binding protein purified from human erythrocyte membraneIdentification and characterization of rain, a novel Ras-interacting protein with a unique subcellular localizationAn Eps homology (EH) domain protein that binds to the Ral-GTPase target, RalBP1Interactions of the amino acid residue at position 31 of the c-Ha-Ras protein with Raf-1 and RalGDSRal GTPases in tumorigenesis: emerging from the shadowsB cell antigen receptor signaling induces the formation of complexes containing the Crk adapter proteinsRalGDS functions in Ras- and cAMP-mediated growth stimulationThe N-terminal pleckstrin, coiled-coil, and IQ domains of the exchange factor Ras-GRF act cooperatively to facilitate activation by calciumRas oncogenes: split personalitiesRal-regulated interaction between Sec5 and paxillin targets Exocyst to focal complexes during cell migration.Ras history: The saga continues.R-Ras regulates exocytosis by Rgl2/Rlf-mediated activation of RalA on endosomes.R-Ras regulates beta1-integrin trafficking via effects on membrane ruffling and endocytosis.Association of RACK1 and PKCbeta with the common beta-chain of the IL-5/IL-3/GM-CSF receptor.Epsin binds to the EH domain of POB1 and regulates receptor-mediated endocytosis.Retrotransposition and mutation events yield Rap1 GTPases with differential signalling capacityRas-Raf-Arf signaling critically depends on the Dmp1 transcription factor.Transcriptional activation of the human proliferating-cell nuclear antigen promoter by p53.
P2860
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P2860
Identification of the guanine nucleotide dissociation stimulator for Ral as a putative effector molecule of R-ras, H-ras, K-ras, and Rap
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
name
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@ast
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@en
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@nl
type
label
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@ast
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@en
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@nl
prefLabel
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@ast
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@en
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@nl
P2860
P356
P1476
Identification of the guanine ...... f R-ras, H-ras, K-ras, and Rap
@en
P2093
J R Bischoff
P2860
P304
P356
10.1073/PNAS.91.26.12609
P407
P577
1994-12-20T00:00:00Z