Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
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P110delta, a novel phosphoinositide 3-kinase in leukocytesMapping the Zap-70 phosphorylation sites on LAT (linker for activation of T cells) required for recruitment and activation of signalling proteins in T cellsAutophosphorylation of p110delta phosphoinositide 3-kinase: a new paradigm for the regulation of lipid kinases in vitro and in vivoPDK1 mediates growth factor-induced Ral-GEF activation by a kinase-independent mechanismThe RAS effector RIN1 directly competes with RAF and is regulated by 14-3-3 proteins.The N-terminal 24 amino acids of the p55 gamma regulatory subunit of phosphoinositide 3-kinase binds Rb and induces cell cycle arrestAssociation of yeast adenylyl cyclase with cyclase-associated protein CAP forms a second Ras-binding site which mediates its Ras-dependent activationp38alpha isoform Mxi2 binds to extracellular signal-regulated kinase 1 and 2 mitogen-activated protein kinase and regulates its nuclear activity by sustaining its phosphorylation levelsNovel hepatocyte growth factor (HGF) binding domains on fibronectin and vitronectin coordinate a distinct and amplified Met-integrin induced signalling pathway in endothelial cellsDifferential responses to doxorubicin-induced phosphorylation and activation of Akt in human breast cancer cells.Molecular mechanisms and functional implications of polarized actin remodeling at the T cell immunological synapseDynamic properties of the Ras switch I region and its importance for binding to effectorsRegulation of the p85/p110 phosphatidylinositol 3'-kinase: stabilization and inhibition of the p110alpha catalytic subunit by the p85 regulatory subunitPS1 activates PI3K thus inhibiting GSK-3 activity and tau overphosphorylation: effects of FAD mutationsHyperactivation of p21(ras) and the hematopoietic-specific Rho GTPase, Rac2, cooperate to alter the proliferation of neurofibromin-deficient mast cells in vivo and in vitroPKCλ is critical in AMPA receptor phosphorylation and synaptic incorporation during LTPStimulation of gene induction and cell growth by the Ras effector RlfRegulation of the PI3K pathway through a p85α monomer-homodimer equilibriumv-Crk activates the phosphoinositide 3-kinase/AKT pathway by utilizing focal adhesion kinase and H-Ras.Mechanisms through which Sos-1 coordinates the activation of Ras and Rac.Phosphatidylinositol 3-kinase is required for integrin-stimulated AKT and Raf-1/mitogen-activated protein kinase pathway activation.Spatial sensing in fibroblasts mediated by 3' phosphoinositides.14-3-3 proteins are required for the inhibition of Ras by exoenzyme S.EGF-induced activation of Akt results in mTOR-dependent p70S6 kinase phosphorylation and inhibition of HC11 cell lactogenic differentiation.RAS and RHO families of GTPases directly regulate distinct phosphoinositide 3-kinase isoforms.c-Met overexpression contributes to the acquired apoptotic resistance of nonadherent ovarian cancer cells through a cross talk mediated by phosphatidylinositol 3-kinase and extracellular signal-regulated kinase 1/2.Human RAS superfamily proteins and related GTPases.Hot-spot mutations in p110alpha of phosphatidylinositol 3-kinase (pI3K): differential interactions with the regulatory subunit p85 and with RAS.Inflammation to cancer: The molecular biology in the pancreas (Review).Epidermal Growth Factor Receptor Cell Proliferation Signaling PathwaysA function for phosphatidylinositol 3-kinase beta (p85alpha-p110beta) in fibroblasts during mitogenesis: requirement for insulin- and lysophosphatidic acid-mediated signal transduction.Expression of migfilin is increased in esophageal cancer and represses the Akt-β-catenin activation.Human cytomegalovirus up-regulates the phosphatidylinositol 3-kinase (PI3-K) pathway: inhibition of PI3-K activity inhibits viral replication and virus-induced signalingRASA1 functions in EPHB4 signaling pathway to suppress endothelial mTORC1 activity.Oxidative signaling in renal epithelium: Critical role of cytosolic phospholipase A2 and p38(SAPK).Akt/PKB regulates laminin and collagen IV isotypes of the basement membraneDifferential roles of Akt, Rac, and Ral in R-Ras-mediated cellular transformation, adhesion, and survival.Thrombopoietin-mediated sustained activation of extracellular signal-regulated kinase in UT7-Mpl cells requires both Ras-Raf-1- and Rap1-B-Raf-dependent pathwaysThe multisubstrate adapter Gab1 regulates hepatocyte growth factor (scatter factor)-c-Met signaling for cell survival and DNA repairOncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.
P2860
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P2860
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
description
1996 nî lūn-bûn
@nan
1996 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1996年の論文
@ja
1996年学术文章
@wuu
1996年学术文章
@zh-cn
1996年学术文章
@zh-hans
1996年学术文章
@zh-my
1996年学术文章
@zh-sg
1996年學術文章
@yue
name
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@ast
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@en
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@nl
type
label
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@ast
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@en
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@nl
prefLabel
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@ast
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@en
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@nl
P2093
P2860
P1433
P1476
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation
@en
P2093
B Vanhaesebroeck
J Downward
M D Waterfield
P Rodriguez-Viciana
P2860
P304
P407
P577
1996-05-15T00:00:00Z