(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer
about
The TES gene at 7q31.1 is methylated in tumours and encodes a novel growth-suppressing LIM domain proteinNegative regulation of the Wnt-beta-catenin pathway by the transcriptional repressor HBP1HMG box transcriptional repressor HBP1 maintains a proliferation barrier in differentiated liver tissueStromal cell expression of caveolin-1 predicts outcome in breast cancerIntragenic amplification and formation of extrachromosomal small circular DNA molecules from the PIP gene on chromosome 7 in primary breast carcinomasGenes encoding human caveolin-1 and -2 are co-localized to the D7S522 locus (7q31.1), a known fragile site (FRA7G) that is frequently deleted in human cancersDown-regulation of caveolin-1, a candidate tumor suppressor gene, in sarcomasCaveolin-1 sensitizes rat pituitary adenoma GH3 cells to bromocriptine induced apoptosisThe membrane-spanning domains of caveolins-1 and -2 mediate the formation of caveolin hetero-oligomers. Implications for the assembly of caveolae membranes in vivoCaveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status.Identification of a new target region on the long arm of chromosome 7 in gastric carcinoma by loss of heterozygosity.Fine-mapping of prostate cancer aggressiveness loci on chromosome 7q22-35.Frequent loss of heterozygosity in the region of the D7S523 locus in advanced ovarian cancer.Molecular anatomy of chromosome 7q deletions in myeloid neoplasms: evidence for multiple critical loci.Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic miceCaveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.Construction of a high-resolution physical map of the approximate 1-Mb region of human chromosome 7q31.1-q31.2 harboring a putative tumor suppressor geneMolecular cytogenetic investigations of synchronous bilateral breast cancer.Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasiaAbsence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation.Caveolin-1 in oncogenic transformation, cancer, and metastasis.Epstein-Barr virus growth-transformed cells are converted to malignancy following transfection of a 1.3-kb CATR1 antisense construct independent of a change in the level of c-myc expression followed by a 8;14 chromosomal translocation.Caveolin-1 expression in benign and malignant lesions of the breast.Genome-wide association study of prognosis in advanced non-small cell lung cancer patients receiving platinum-based chemotherapy.A new frontier in personalized cancer therapy: mapping molecular changes.The role of caveolin-1 in human breast cancer.Estrogen receptor alpha-mediated silencing of caveolin gene expression in neuronal cells.Definitive functional evidence for a tumor suppressor gene on human chromosome 7q31.1 neighboring the Fra7G site.Fish mapping of YAC clones at human chromosomal band 7q31.2: identification of YACS spanning FRA7G within the common region of LOH in breast and prostate cancer.Gene therapy strategies for carcinoma of the breast.Commonly deleted region on the long arm of chromosome 7 in differentiated adenocarcinoma of the stomachConformational transitions of alternating purine-pyrimidine DNAs in perchlorate ethanol solutions.Prostate cancer aggressiveness locus on chromosome 7q32-q33 identified by linkage and allelic imbalance studies.Analysis of the CAVEOLIN-1 gene at human chromosome 7q31.1 in primary tumours and tumour-derived cell lines.Frequent allelic loss at 7p14-15 associated with aggressive histologic types of breast cancer.Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1)Caveolin-1 inhibits breast cancer growth and metastasisGenetic and epigenetic modification of mismatch repair genes hMSH2 and hMLH1 in sporadic breast cancer with microsatellite instabilityEuropean Gene Mapping Project (EUROGEM): Breakpoint panels for human chromosomes based on the CEPH reference families
P2860
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P2860
(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer
description
1994 nî lūn-bûn
@nan
1994 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1994 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
1994年の論文
@ja
1994年学术文章
@wuu
1994年学术文章
@zh-cn
1994年学术文章
@zh-hans
1994年学术文章
@zh-my
1994年学术文章
@zh-sg
1994年學術文章
@yue
name
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@ast
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@en
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@nl
type
label
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@ast
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@en
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@nl
prefLabel
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@ast
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@en
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@nl
P2093
P2860
P356
P1476
(C-A)n microsatellite repeat D ...... in human primary breast cancer
@en
P2093
J C Zenklusen
R Lidereau
P2860
P304
12155-12158
P356
10.1073/PNAS.91.25.12155
P407
P50
P577
1994-12-01T00:00:00Z