Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

Item

http://www.wikidata.org/entity/Q35789293

Q35789293

about

The caveolin proteins Identification of a novel domain at the N terminus of caveolin-1 that controls rear polarization of the protein and caveolae formation Assembly and Turnover of Caveolae: What Do We Really Know?Caveolin-1, a stress-related oncotarget, in drug resistance Co-regulation of cell polarization and migration by caveolar proteins PTRF/Cavin-1 and caveolin-1 Murine Models of Splenic Marginal Zone Lymphoma: A Role for Cav1?Signal transducer and activator of transcription 5A/B in prostate and breast cancers Loss of caveolin-3 induces a lactogenic microenvironment that is protective against mammary tumor formation Rab6-mediated retrograde transport regulates inner nuclear membrane targeting of caveolin-2 in response to insulin Caveolin-1 knockout mice show an impaired angiogenic response to exogenous stimuli Endolysosomal sorting of ubiquitylated caveolin-1 is regulated by VCP and UBXD1 and impaired by VCP disease mutations Phospho-caveolin-1 mediates integrin-regulated membrane domain internalization.Cholesterol and fatty acids regulate dynamic caveolin trafficking through the Golgi complex and between the cell surface and lipid bodies.Plasma membrane domain organization regulates EGFR signaling in tumor cells Caveolin-1 mutations in human breast cancer: functional association with estrogen receptor alpha-positive status.Caveolin-1: a tumor-promoting role in human cancer.Absence of the caveolin-1 P132L mutation in cancers of the breast and other organs.A role for caveolin 1 in assembly and budding of the paramyxovirus parainfluenza virus 5.Common fragile site tumor suppressor genes and corresponding mouse models of cancer.Identification of genetic networks Loss of caveolin-1 gene expression accelerates the development of dysplastic mammary lesions in tumor-prone transgenic mice RNAi screen of Salmonella invasion shows role of COPI in membrane targeting of cholesterol and Cdc42 Caveolin-1 deficiency (-/-) conveys premalignant alterations in mammary epithelia, with abnormal lumen formation, growth factor independence, and cell invasiveness.Simultaneous expression of caveolin-1 and E-cadherin in ovarian carcinoma cells stabilizes adherens junctions through inhibition of src-related kinases Stromal and epithelial caveolin-1 both confer a protective effect against mammary hyperplasia and tumorigenesis: Caveolin-1 antagonizes cyclin D1 function in mammary epithelial cells.Caveolins, caveolae, and lipid rafts in cellular transport, signaling, and disease.Absence of caveolin-1 sensitizes mouse skin to carcinogen-induced epidermal hyperplasia and tumor formation.Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy.Affinity-Guided Design of Caveolin-1 Ligands for Deoligomerization.Caveolin-1 in oncogenic transformation, cancer, and metastasis.Molecular Characterization of Caveolin-induced Membrane Curvature.Loss of caveolin-1 alters extracellular matrix protein expression and ductal architecture in murine mammary glands CAVEOLIN-1 expression in brain metastasis from lung cancer predicts worse outcome and radioresistance, irrespective of tumor histotype.Regulation of Cripto-1 signaling and biological activity by caveolin-1 in mammary epithelial cells Clinical significance of Caveolin-1, Caveolin-2 and HER2/neu mRNA expression in human breast cancer.Dysfunctional intracellular trafficking in the pathobiology of pulmonary arterial hypertension.Pulmonary arterial hypertension: a disease of tethers, SNAREs and SNAPs?Overexpression of caveolin-1 is sufficient to phenocopy the behavior of a disease-associated mutant Integrin trafficking and its role in cancer metastasis.Lipid rafts and caveolae in signaling by growth factor receptors.

P2860

Q21194854-4A9D17CE-55BC-4BAA-9D93-70E08D1726C1 Q23923938-C2424C69-0EA7-4FB2-8607-1CAAE340B1AE Q26742079-F567AAAB-1071-4881-ABC7-6B0ECD0477E7 Q26782615-07241F69-517B-42F9-A2DA-5D5F011C7A04 Q27324084-D0C2D365-5004-4C78-9B1F-D46F0416F3F1 Q28070123-E730D23D-CBC5-415E-8EEF-8B5827F60E40 Q28281791-4463C960-D214-4681-88E2-5E0D70F1F751 Q28508528-472949A6-1410-4BF6-B4AF-C4719FEE0138 Q28581769-17C796CA-E17B-4DBD-90AB-EB6E5EE66B98 Q28587327-9EA84058-B13D-499E-BCB4-2B362DAE8D3C Q30179386-E1A3C14E-0916-4890-B164-07D4825B448B Q30447025-8BEB3EA5-8CE1-4066-A966-262E88C159A5 Q30475819-196B6792-B535-4066-9E4D-A5900C2D1B75 Q30480578-C27D7BC9-73C4-4A04-947C-95213B1598F6 Q33244639-9DFAF14D-94CF-4BB1-A3C1-73F99B0EB29A Q34010128-4AB1B8E0-0712-4F18-A91B-AFC4C3537D13 Q34084878-768C6317-E2AD-418C-BB10-8E62500EAC26 Q34120941-9467BB49-5686-4F99-AAEC-63B37E74B09D Q34557827-5E56C447-ACEE-43C9-9955-ABA4DE2DF60A Q34643738-80C6EBE3-16E4-4BA2-81BD-319B62AEDF8D Q34813351-D6E033EA-B5DC-476F-A3FE-1ECB3A9D5834 Q34979713-9818E89A-E4D3-4729-A112-62A7B74F7EB7 Q35070726-71FFCE2E-5F2B-4835-B174-C4054E907990 Q35085393-D3EF2AF8-284E-405C-AF29-D3EFE4563807 Q35607385-CFBC8840-27AF-46EC-ADD9-F435DE2115BE Q35723460-64801735-D0C4-4639-AE02-B657795FEA44 Q35791457-435D96EC-4803-4E5F-B5F1-732E6D4DDFCB Q35871506-EA41DA20-F2A2-4E1C-AE4B-AA4897068728 Q35968549-DF13464B-F19B-4169-A9C7-78E8435F4CDF Q36030347-794C0A6F-ED74-4B3D-A397-6E37D23C92A5 Q36139854-EF406206-23D1-4BB7-AB1F-35E31C2FFE8E Q36276995-6CBC2CCE-9B38-48D6-8B56-070374675D57 Q36557389-8F94607C-ECE9-4D6D-BFED-91D527AAA541 Q36559674-941AF557-6C41-4C24-8C62-3A6541350D1B Q36695595-12381FC5-B0A7-4B88-8F29-C49066DA4624 Q36761071-D66479EF-A191-494B-B03C-BC352A01E912 Q36784800-1F0DFD1A-A848-476E-863A-53AE808666C2 Q36907381-881636F0-9FAA-4422-B7E1-77057CD36A03 Q36929556-4E702BC6-D439-4B40-8DA7-62401D1B1542 Q36944094-BA09ADF4-3FC2-4E3A-9FDE-21FEC9851DA2

P2860

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

Item

http://www.wikidata.org/entity/Q35789293

description

2002 nî lūn-bûn

@nan

2002年の論文

@ja

2002年論文

@yue

2002年論文

@zh-hant

2002年論文

@zh-hk

2002年論文

@zh-mo

2002年論文

@zh-tw

2002年论文

@wuu

2002年论文

@zh

2002年论文

@zh-cn

name

Caveolin-1 mutations (P132L an ...... ry epithelial cell hyperplasia

@ast

Caveolin-1 mutations (P132L an ...... ry epithelial cell hyperplasia

@en

type

Item

label

Caveolin-1 mutations (P132L an ...... ry epithelial cell hyperplasia

@ast

Caveolin-1 mutations (P132L an ...... ry epithelial cell hyperplasia

@en

prefLabel

Caveolin-1 mutations (P132L an ...... ry epithelial cell hyperplasia

@ast

Caveolin-1 mutations (P132L an ...... ry epithelial cell hyperplasia

@en

P1476

Caveolin-1 mutations (P132L an ...... ry epithelial cell hyperplasia

@en

P2093

Babak Razani

http://www.w3.org/2001/XMLSchema#string

David S Park

http://www.w3.org/2001/XMLSchema#string

Hyangkyu Lee

http://www.w3.org/2001/XMLSchema#string

Richard G Pestell

http://www.w3.org/2001/XMLSchema#string

Robert G Russell

http://www.w3.org/2001/XMLSchema#string

P2860

Identification, sequence, and expression of caveolin-2 defines a caveolin gene family

Reciprocal regulation of neu tyrosine kinase activity and caveolin-1 protein expression in vitro and in vivo. Implications for human breast cancer

Myristoylation and differential palmitoylation of the HCK protein-tyrosine kinases govern their attachment to membranes and association with caveolae

Cell-type and tissue-specific expression of caveolin-2. Caveolins 1 and 2 co-localize and form a stable hetero-oligomeric complex in vivo

Molecular genetics of the caveolin gene family: implications for human cancers, diabetes, Alzheimer disease, and muscular dystrophy.

(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer

Cab45, a novel (Ca2+)-binding protein localized to the Golgi lumen

Human caveolin-1 and caveolin-2 are closely linked genes colocalized with WI-5336 in a region of 7q31 frequently deleted in tumors

Sequence and detailed organization of the human caveolin-1 and -2 genes located near the D7S522 locus (7q31.1). Methylation of a CpG island in the 5' promoter region of the caveolin-1 gene in human breast cancer cell lines

Loss of heterozygosity in human primary prostate carcinomas: a possible tumor suppressor gene at 7q31.1

P304

1357-1369

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1016/S0002-9440(10)64412-4

http://www.w3.org/2001/XMLSchema#string

P407

English

P433

http://www.w3.org/2001/XMLSchema#string

P478

161

http://www.w3.org/2001/XMLSchema#string

P50

Michael P. Lisanti

P577

2002-10-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

12368209

http://www.w3.org/2001/XMLSchema#string

P932

1867297

http://www.w3.org/2001/XMLSchema#string

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

about

P2860

P2860

Caveolin-1 mutations (P132L and null) and the pathogenesis of breast cancer: caveolin-1 (P132L) behaves in a dominant-negative manner and caveolin-1 (-/-) null mice show mammary epithelial cell hyperplasia

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P407

P433

P478

P50

P577

P698

P932