Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
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Wnt/beta-catenin signaling activates microRNA-181 expression in hepatocellular carcinomaTargeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signalingMultiple myeloma cancer stem cellsMicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow MicroenvironmentCancer stem cells are the cause of drug resistance in multiple myeloma: fact or fiction?Heparan sulfate proteoglycans in the control of B cell development and the pathogenesis of multiple myelomaDrug resistance in multiple myeloma: latest findings and new concepts on molecular mechanisms.The EMT activator ZEB1 promotes tumor growth and determines differential response to chemotherapy in mantle cell lymphoma.Epigenetic dysregulation of Wnt signaling pathway in multiple myelomaWIKI4, a novel inhibitor of tankyrase and Wnt/ß-catenin signalingCanonical Wnt pathway inhibitor ICG-001 induces cytotoxicity of multiple myeloma cells in Wnt-independent mannerWnt signalling in stem cells and cancerWNT and beta-catenin signalling: diseases and therapiesStromal fibroblasts in cancer initiation and progressionWnt expression and canonical Wnt signaling in human bone marrow B lymphopoiesisExtracellular sulfatases, elements of the Wnt signaling pathway, positively regulate growth and tumorigenicity of human pancreatic cancer cellsA first-in-human phase I dose-escalation, pharmacokinetic, and pharmacodynamic evaluation of intravenous LY2090314, a glycogen synthase kinase 3 inhibitor, administered in combination with pemetrexed and carboplatin.An open-label phase 2 study of glycogen synthase kinase-3 inhibitor LY2090314 in patients with acute leukemia.Inhibition of canonical WNT signaling attenuates human leiomyoma cell growthGrowth factors in multiple myeloma: a comprehensive analysis of their expression in tumor cells and bone marrow environment using Affymetrix microarrays.Glycogen Synthase Kinase-3 regulates multiple myeloma cell growth and bortezomib-induced cell deathOsteoblastogenesis and tumor growth in myeloma.Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myelomaInput of DNA microarrays to identify novel mechanisms in multiple myeloma biology and therapeutic applications.Fibroblast activation protein protects bortezomib-induced apoptosis in multiple myeloma cells through β-catenin signaling pathwayMultiple myeloma mesenchymal stromal cells: Contribution to myeloma bone disease and therapeuticsGene expression of anti- and pro-apoptotic proteins in malignant and normal plasma cells.Decreased SFRP2 expression is associated with intermediate and poor karyotypes in de novo acute myeloid leukemiaTranscriptional silencing of the Wnt-antagonist DKK1 by promoter methylation is associated with enhanced Wnt signaling in advanced multiple myelomaDifferential expression of DKK-1 binding receptors on stromal cells and myeloma cells results in their distinct response to secreted DKK-1 in myeloma.Crosstalk between microRNA30a/b/c/d/e-5p and the canonical Wnt pathway: implications for multiple myeloma therapyAV-65, a novel Wnt/β-catenin signal inhibitor, successfully suppresses progression of multiple myeloma in a mouse model.Wnt inhibition leads to improved chemosensitivity in paediatric acute lymphoblastic leukaemiaPyk2 promotes tumor progression in multiple myelomaActivation of β-catenin signalling leads to temporomandibular joint defects.MUC1 oncoprotein promotes growth and survival of human multiple myeloma cells.β-catenin SUMOylation is involved in the dysregulated proliferation of myeloma cellsBCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.The mitogen-activated protein kinase kinase kinase kinase GCKR positively regulates canonical and noncanonical Wnt signaling in B lymphocytes.Wnt modulates MCL1 to control cell survival in triple negative breast cancer.
P2860
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P2860
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
description
2004 nî lūn-bûn
@nan
2004 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@ast
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@en
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@nl
type
label
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@ast
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@en
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@nl
prefLabel
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@ast
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@en
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@nl
P2093
P2860
P3181
P356
P1476
Illegitimate WNT signaling promotes proliferation of multiple myeloma cells
@en
P2093
Andries C Bloem
Esther Tjin
Harold D MacGillavry
Helen P Meijer
Henk M Lokhorst
Marinus H J van Oers
Melanie D Klok
Patrick W B Derksen
Roel Nusse
Ronald van der Neut
P2860
P304
P3181
P356
10.1073/PNAS.0305855101
P407
P577
2004-04-20T00:00:00Z