BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells. - Wikidata - awgldk - TriplyDB

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.

http://www.wikidata.org/entity/Q35063960

about

An intrinsically labile α-helix abutting the BCL9-binding site of β-catenin is required for its inhibition by carnosic acid Targeted disruption of the BCL9/β-catenin complex inhibits oncogenic Wnt signaling MicroRNAs: Novel Crossroads between Myeloma Cells and the Bone Marrow Microenvironment Different Facets of Copy Number Changes: Permanent, Transient, and Adaptive The immunological effect of hyaluronan in tumor angiogenesis The many faces and functions of β-catenin Allosteric Remodelling of the Histone H3 Binding Pocket in the Pygo2 PHD Finger Triggered by Its Binding to the B9L/BCL9 Co-Factor A meta-analysis of multiple matched copy number and transcriptomics data sets for inferring gene regulatory relationships.Sonic hedgehog acts as a negative regulator of {beta}-catenin signaling in the adult tongue epithelium.Comparative analysis of RNA-Seq alignment algorithms and the RNA-Seq unified mapper (RUM).Cytogenetic as an important tool for diagnosis and prognosis for patients with hypocellular primary myelodysplastic syndrome.Copy number analysis identifies novel interactions between genomic loci in ovarian cancer Impaired CK1 delta activity attenuates SV40-induced cellular transformation in vitro and mouse mammary carcinogenesis in vivo Crosstalk between microRNA30a/b/c/d/e-5p and the canonical Wnt pathway: implications for multiple myeloma therapy Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development.Histotype-specific copy-number alterations in ovarian cancer.FOXP1 potentiates Wnt/β-catenin signaling in diffuse large B cell lymphoma.Stromal interaction essential for vascular endothelial growth factor A-induced tumour growth via transforming growth factor-β signalling A Sleeping Beauty mutagenesis screen reveals a tumor suppressor role for Ncoa2/Src-2 in liver cancer.The Cyclophilin A-CD147 complex promotes the proliferation and homing of multiple myeloma cells.Expression profiling of in vivo ductal carcinoma in situ progression models identified B cell lymphoma-9 as a molecular driver of breast cancer invasion The role of upregulated miRNAs and the identification of novel mRNA targets in prostatospheres Genome-wide pharmacologic unmasking identifies tumor suppressive microRNAs in multiple myeloma.BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer.Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival.BCL9, a coactivator for Wnt/β-catenin transcription, is targeted by miR-30c and is associated with prostate cancer progression.Endogenous transmembrane protein UT2 inhibits pSTAT3 and suppresses hematological malignancy TRIM13 (RFP2) downregulation decreases tumour cell growth in multiple myeloma through inhibition of NF Kappa B pathway and proteasome activity.Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia Hypoxia activates Wnt/β-catenin signaling by regulating the expression of BCL9 in human hepatocellular carcinoma.The iron chelator deferasirox induces apoptosis by targeting oncogenic Pyk2/β-catenin signaling in human multiple myeloma.Role of BCL9L in transforming growth factor-β (TGF-β)-induced epithelial-to-mesenchymal-transition (EMT) and metastasis of pancreatic cancer.miR-30-5p functions as a tumor suppressor and novel therapeutic tool by targeting the oncogenic Wnt/β-catenin/BCL9 pathway.Intestinal stem cell overproliferation resulting from inactivation of the APC tumor suppressor requires the transcription cofactors Earthbound and Erect wing.JRK is a positive regulator of β-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer.Decreased miR-30b-5p expression by DNMT1 methylation regulation involved in gastric cancer metastasis.LEF1 and B9L shield β-catenin from inactivation by Axin, desensitizing colorectal cancer cells to tankyrase inhibitors.β-catenin is dynamically stored and cleared in multiple myeloma by the proteasome-aggresome-autophagosome-lysosome pathway.miR-30a acts as a tumor suppressor by double-targeting COX-2 and BCL9 in H. pylori gastric cancer models.Argonaute CLIP Defines a Deregulated miR-122-Bound Transcriptome that Correlates with Patient Survival in Human Liver Cancer.

P2860

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P2860

BCL9 promotes tumor progression by conferring enhanced proliferative, metastatic, and angiogenic properties to cancer cells.

http://www.wikidata.org/entity/Q35063960

description

2009 nî lūn-bûn

@nan

2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

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2009年論文

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2009年論文

@zh-hk

2009年論文

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2009年論文

@zh-tw

2009年论文

@wuu

name

BCL9 promotes tumor progressio ...... ic properties to cancer cells.

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BCL9 promotes tumor progressio ...... ic properties to cancer cells.

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type

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BCL9 promotes tumor progressio ...... ic properties to cancer cells.

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BCL9 promotes tumor progressio ...... ic properties to cancer cells.

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prefLabel

BCL9 promotes tumor progressio ...... ic properties to cancer cells.

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BCL9 promotes tumor progressio ...... ic properties to cancer cells.

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0008-5472.CAN-09-0773

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Cancer Research

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BCL9 promotes tumor progressio ...... ic properties to cancer cells.

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Daniel E Carrasco

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Daniel R Carrasco

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Felipe Diaz-Griffero

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Hiroshi Ikeda

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Jui Dutta-Simmons

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Kohichi Takada

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Lois L Myeroff

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Mala Mani

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Monica Bertagnolli

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Moshe E Gatt

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P2860

Bioconductor: open software development for computational biology and bioinformatics

Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex

The RAB25 small GTPase determines aggressiveness of ovarian and breast cancers

Identification of c-MYC as a target of the APC pathway

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling

Essential role of BCL9-2 in the switch between beta-catenin's adhesive and transcriptional functions

Illegitimate WNT signaling promotes proliferation of multiple myeloma cells

Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma

Beta-catenin regulates expression of cyclin D1 in colon carcinoma cells

Linear models and empirical bayes methods for assessing differential expression in microarray experiments

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7577-7586

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scholarly article

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10.1158/0008-5472.CAN-09-0773

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19

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69

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Kenneth C Anderson

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2009-09-08T00:00:00Z

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19738061

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4321734

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