Cutting edge: The transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy
about
Ubiquitin in the immune systemThe structural basis of R-spondin recognition by LGR5 and RNF43Does antigen masking by ubiquitin chains protect from the development of autoimmune diseases?The PA-TM-RING protein RING finger protein 13 is an endosomal integral membrane E3 ubiquitin ligase whose RING finger domain is released to the cytoplasm by proteolysisE3 ubiquitin ligase GRAIL controls primary T cell activation and oral toleranceNaive CD4 t cell proliferation is controlled by mammalian target of rapamycin regulation of GRAIL expressionThe E3 ubiquitin ligase GRAIL regulates T cell tolerance and regulatory T cell function by mediating T cell receptor-CD3 degradation.Ethylenecarbodiimide-treated splenocytes carrying male CD4 epitopes confer histocompatibility Y chromosome antigen transplant protection by inhibiting CD154 upregulation.Preformed CD40L is stored in Th1, Th2, Th17, and T follicular helper cells as well as CD4+ 8- thymocytes and invariant NKT cells but not in Treg cells.The transmembrane E3 ligase GRAIL ubiquitinates and degrades CD83 on CD4 T cells.GRAIL (gene related to anergy in lymphocytes) regulates cytoskeletal reorganization through ubiquitination and degradation of Arp2/3 subunit 5 and coronin 1ANFAT1 supports tumor-induced anergy of CD4(+) T cellsGRAIL and Otubain-1 are Related to T Cell Hyporesponsiveness during Trypanosoma cruzi InfectionMannose-Capped Lipoarabinomannan from Mycobacterium tuberculosis Induces CD4+ T Cell Anergy via GRAILAttenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation.E3 ubiquitin ligases in T-cell tolerance.Regulation of T-cell tolerance by calcium/NFAT signaling.Upregulation of GRAIL is associated with impaired CD4 T cell proliferation in sepsis.GRAIL: a unique mediator of CD4 T-lymphocyte unresponsiveness.RNF13: an emerging RING finger ubiquitin ligase important in cell proliferation.Induction and stability of the anergic phenotype in T cellsThe Role of the Transmembrane RING Finger Proteins in Cellular and Organelle FunctionUbiquitin enzymes in the regulation of immune responses.E3 ubiquitin ligase RNF128 promotes innate antiviral immunity through K63-linked ubiquitination of TBK1.The protease-associated domain and C-terminal extension are required for zymogen processing, sorting within the secretory pathway, and activity of tomato subtilase 3 (SlSBT3).CD40 Ligand Is Increased in Mast Cells in Psoriasis and Actinic Keratosis but Less So in Epithelial Skin Carcinomas.Nuclear targeting of an endosomal E3 ubiquitin ligase.Tumour-associated mutations of PA-TM-RING ubiquitin ligases RNF167/RNF13 identify the PA domain as a determinant for endosomal localization.Fine-tuning of thymocyte development by ubiquitination-mediated stability control of the ESCRT protein CHMP5.CRYAB modulates the activation of CD4+ T cells from relapsing-remitting multiple sclerosis patients.Regulation of anergy-related ubiquitin E3 ligase, GRAIL, in murine models of colitis and patients with Crohn's disease.
P2860
Q26998711-C7951002-BA9D-42DD-AB9D-3174EF639BEDQ27678577-C210378D-FB3E-432F-B955-2227CD9C2543Q28387136-0D70D2C3-C65D-4B01-9C38-887041A19D1BQ28510158-7EDD928D-B503-46FE-8949-B3F0AA178ED9Q28750747-907B42B1-F8E2-4E1A-A2DA-2D1F73ED1ED9Q33784244-C97AE6D5-7B0A-43F1-B9DE-476CE8168078Q34041946-DFCD26DC-A000-4E0C-89C8-B3B69D58C9D7Q34103866-ACC2E6D2-0876-434A-9C45-184491CB0C05Q34170759-7B7E4E9E-4BA1-454E-906E-10624B04921EQ34989042-570E32C9-C346-4417-85D9-444A509550C3Q35604557-D1117A2E-53D0-4267-A46E-085FA92972CFQ36243594-73F428B3-D7A9-440E-897B-CA0747D2636BQ36257442-DB99BB88-31D9-4F51-B9F4-4872EE55A133Q36447752-6804A3E3-9FF3-4E67-986B-3A11B6A2F8CDQ36473888-4524AC47-FF8E-4465-A1DA-EB9BC5966655Q37588591-13D74977-B79C-4FC6-9383-F91CDE327343Q37597631-F6CAB614-0A49-43CA-890F-E63BF9D32102Q37620045-E1D6BB6C-A934-4E52-8D33-7C976E03FB38Q37809578-1A3D13D7-0A2A-4FEA-9162-C121299AD19EQ37809582-7F03E7C6-EDBF-4721-B113-72A0232DB858Q38161200-B8357C6E-0F49-4DE0-BDA9-C3EDB06FD277Q38222629-515A65AB-88A2-4AE3-B76C-05ACD0B93FF4Q39317949-566681D8-2FC7-49B0-AF88-BCA94E534094Q40476073-EB6AABBF-ACBC-40C6-81B3-EAE95C3193B6Q42233009-2511540C-0552-4E76-893C-40B2C314661CQ42506621-051F7307-BAFD-4A07-A4FA-5399C3173CDDQ43129322-FD05DEE3-AD68-451E-9DF0-95C360E58D18Q46124826-039E2835-F76F-4CAE-904B-5ED19CFEAEFEQ47825435-105E9920-D9EC-48C2-A635-652E7153051EQ50937116-6DF3CAB8-F7AF-4A2C-B7BB-F98AB8A91935Q54415092-4C52B8E8-B930-4084-A155-7E5A8CDA8864
P2860
Cutting edge: The transmembrane E3 ligase GRAIL ubiquitinates the costimulatory molecule CD40 ligand during the induction of T cell anergy
description
2008 nî lūn-bûn
@nan
2008 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2008年の論文
@ja
2008年論文
@yue
2008年論文
@zh-hant
2008年論文
@zh-hk
2008年論文
@zh-mo
2008年論文
@zh-tw
2008年论文
@wuu
name
Cutting edge: The transmembran ...... the induction of T cell anergy
@ast
Cutting edge: The transmembran ...... the induction of T cell anergy
@en
Cutting edge: The transmembran ...... the induction of T cell anergy
@nl
type
label
Cutting edge: The transmembran ...... the induction of T cell anergy
@ast
Cutting edge: The transmembran ...... the induction of T cell anergy
@en
Cutting edge: The transmembran ...... the induction of T cell anergy
@nl
prefLabel
Cutting edge: The transmembran ...... the induction of T cell anergy
@ast
Cutting edge: The transmembran ...... the induction of T cell anergy
@en
Cutting edge: The transmembran ...... the induction of T cell anergy
@nl
P2093
P2860
P1476
Cutting edge: The transmembran ...... the induction of T cell anergy
@en
P2093
C Garrison Fathman
Christine M Seroogy
Greg P Coffey
Jack T Lin
Neil B Lineberry
P2860
P304
P356
10.4049/JIMMUNOL.181.3.1622
P407
P577
2008-08-01T00:00:00Z