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Wnt/beta-catenin signaling and small molecule inhibitors

Wnt/beta-catenin signaling and small molecule inhibitors

http://www.wikidata.org/entity/Q24597197

about

β catenin in health: A review Polyphenol Compound as a Transcription Factor Inhibitor Organ In Vitro Culture: What Have We Learned about Early Kidney Development?Flavonoids and Wnt/β-catenin signaling: potential role in colorectal cancer therapies A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection Protein kinase A-dependent pSer(675) -β-catenin, a novel signaling defect in a mouse model of congenital hepatic fibrosis The Epigenomics of Embryonic Pathway Signaling in Colorectal Cancer.Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs.The CREB-binding protein inhibitor ICG-001 suppresses pancreatic cancer growth.β-catenin links von Hippel-Lindau to aurora kinase A and loss of primary cilia in renal cell carcinoma.Catalytic enantioselective 1,3-dipolar cycloadditions of azomethine ylides for biology-oriented synthesis.Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma.Identification of targets for rational pharmacological therapy in childhood craniopharyngioma.Precise Classification of Cervical Carcinomas Combined with Somatic Mutation Profiling Contributes to Predicting Disease Outcome.Suppression of Hepatocellular Carcinoma by Inhibition of Overexpressed Ornithine Aminotransferase Small-molecule inhibitors of Wnt signaling pathway: towards novel anticancer therapeutics.A kinome siRNA screen identifies HGS as a potential target for liver cancers with oncogenic mutations in CTNNB1.miR-9 Acts as an OncomiR in Prostate Cancer through Multiple Pathways That Drive Tumour Progression and Metastasis.Potential Therapeutic Targets in Uterine Sarcomas.Genomic and transcriptome profiling identified both human and HBV genetic variations and their interactions in Chinese hepatocellular carcinoma.MiR-1207 overexpression promotes cancer stem cell-like traits in ovarian cancer by activating the Wnt/β-catenin signaling pathway.GalNAc-T14 promotes metastasis through Wnt dependent HOXB9 expression in lung adenocarcinoma MEKK2 mediates an alternative β-catenin pathway that promotes bone formation IDO1 metabolites activate β-catenin signaling to promote cancer cell proliferation and colon tumorigenesis in mice Aberrant expression of nuclear HDAC3 and cytoplasmic CDH1 predict a poor prognosis for patients with pancreatic cancer ROR2 is epigenetically inactivated in the early stages of colorectal neoplasia and is associated with proliferation and migration Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling Transglutaminase 2 as a novel activator of LRP6/β-catenin signaling.Epigenetic modulation of signal transduction pathways in HPV-associated HNSCC.Activation of the Wnt Pathway by Mycobacterium tuberculosis: A Wnt-Wnt Situation.Heart regeneration: opportunities and challenges for drug discovery with novel chemical and therapeutic methods or agents.Tankyrases: structure, function and therapeutic implications in cancer.Targeting the canonical Wnt/β-catenin pathway in hematological malignancies.The role of the Wnt signaling pathway in cancer stem cells: prospects for drug development.The Wnt signaling pathway in cancer.Protein kinase C ϵ stabilizes β-catenin and regulates its subcellular localization in podocytes.Wnt/Beta-Catenin Signal Inhibitor HC-1 Sensitizes Oral Squamous Cell Carcinoma Cells to 5-Fluorouracil through Reduction of CD44-Positive Population.Knockdown of β-catenin by siRNA influences proliferation, apoptosis and invasion of the colon cancer cell line SW480 Pharmacologic Wnt Inhibition Reduces Proliferation, Survival, and Clonogenicity of Glioblastoma Cells.Pharmacological folding chaperones act as allosteric ligands of Frizzled4.

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Wnt/beta-catenin signaling and small molecule inhibitors

http://www.wikidata.org/entity/Q24597197

description

2013 nî lūn-bûn

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2013 թուականին հրատարակուած գիտական յօդուած

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2013 թվականին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Wnt/beta-catenin signaling and small molecule inhibitors

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Current Pharmaceutical Design

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Wnt/beta-catenin signaling and small molecule inhibitors

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Andrey Voronkov

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Stefan Krauss

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Creative Commons Attribution 2.5 Unported

P2860

Tankyrase, a poly(ADP-ribose) polymerase at human telomeres

Pontin52, an interaction partner of beta-catenin, binds to the TATA box binding protein

The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis

Protein phosphatase 2Calpha dephosphorylates axin and activates LEF-1-dependent transcription

GSK-3beta-dependent phosphorylation of adenomatous polyposis coli gene product can be modulated by beta-catenin and protein phosphatase 2A complexed with Axin

Differential mechanisms of LEF/TCF family-dependent transcriptional activation by beta-catenin and plakoglobin

Mutations in AXIN2 cause colorectal cancer with defective mismatch repair by activating beta-catenin/TCF signalling

LDL-receptor-related proteins in Wnt signal transduction

Phosphorylation and inactivation of glycogen synthase kinase 3 by protein kinase A

Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF beta receptor for degradation

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scholarly article

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10.2174/138161213804581837

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19

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2013-01-01T00:00:00Z

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23016862

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transcription factor

armadillo domain proteins

cytoskeletal proteins

biomedical investigative technique

P932

3529405

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