about
A new reagent for direct difluoromethylationSynthetic Organic Electrochemistry: An Enabling and Innately Sustainable MethodRadicals: Reactive Intermediates with Translational PotentialInnate and Guided C–H Functionalization LogicMetal-free C-H alkylation of heteroarenes with alkyltrifluoroborates: a general protocol for 1°, 2° and 3° alkylation.Potent fluorinated agelastatin analogues for chronic lymphocytic leukemia: design, synthesis, and pharmacokinetic studiesPreparation and purification of zinc sulfinate reagents for drug discovery.Synthetic and mechanistic aspects of the regioselective base-mediated reaction of perfluoroalkyl- and perfluoroarylsilanes with heterocyclic N-oxidesTrifluoromethylation of arenes and heteroarenes by means of photoredox catalysis.Tamed arene and heteroarene trifluoromethylation.Divergent synthesis of novel 9-deazaxanthine derivatives via late-stage cross-coupling reactions.Late-stage functionalization of biologically active heterocycles through photoredox catalysis.Academia-industry symbiosis in organic chemistry.Palladium-catalyzed intramolecular C-H difluoroalkylation: synthesis of substituted 3,3-difluoro-2-oxindoles.Iron(II)-catalyzed trifluoromethylation of potassium vinyltrifluoroboratesFree Radical Chemistry Enabled by Visible Light-Induced Electron Transfer.Copper-catalyzed oxytrifluoromethylation of unactivated alkenes.Copper-Catalyzed Aerobic C-H Trifluoromethylation of Phenanthrolines.Non-covalent interactions involving halogenated derivatives of capecitabine and thymidylate synthase: a computational approach.Dehydrogenative alkenylation of uracils via palladium-catalyzed regioselective C-H activation.4-Trifluoromethyl-p-quinols as dielectrophiles: three-component, double nucleophilic addition/aromatization reactions.Chemistry and pharmacological studies of 3-alkoxy-2,5-disubstituted-pyridinyl compounds as novel selective α4β2 nicotinic acetylcholine receptor ligands that reduce alcohol intake in ratsRecent advances in transition metal-catalyzed Csp(2)-monofluoro-, difluoro-, perfluoromethylation and trifluoromethylthiolation.Rapid and efficient trifluoromethylation of aromatic and heteroaromatic compounds using potassium trifluoroacetate enabled by a flow system.Recent developments on the trifluoromethylation of (hetero)arenes.Catalytic selective synthesis.Introduction of fluorine and fluorine-containing functional groups.The electron is a catalyst.Transitioning organic synthesis from organic solvents to water. What's your E Factor?Sulfinate derivatives: dual and versatile partners in organic synthesis.Recent advances in fluorination techniques and their anticipated impact on drug metabolism and toxicity.Practical radical cyclizations with arylboronic acids and trifluoroborates.C-H methylation of heteroarenes inspired by radical SAM methyl transferase.Copper-mediated perfluoroalkylation of heteroaryl bromides with (phen)CuRF.Methyl fluorosulfonyldifluoroacetate (MFSDA): An Underutilised Reagent for Trifluoromethylation.Silver-mediated trifluoromethylation of arenes using TMSCF3.Trifluoromethylation of Heterocycles in Water at Room TemperatureDirect synthesis of fluorinated heteroarylether bioisosteres.Late-stage deoxyfluorination of alcohols with PhenoFluor.Halogen-directed drug design for Alzheimer's disease: a combined density functional and molecular docking study.
P2860
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P2860
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Innate C-H trifluoromethylation of heterocycles
@ast
Innate C-H trifluoromethylation of heterocycles
@en
Innate C-H trifluoromethylation of heterocycles
@nl
type
label
Innate C-H trifluoromethylation of heterocycles
@ast
Innate C-H trifluoromethylation of heterocycles
@en
Innate C-H trifluoromethylation of heterocycles
@nl
prefLabel
Innate C-H trifluoromethylation of heterocycles
@ast
Innate C-H trifluoromethylation of heterocycles
@en
Innate C-H trifluoromethylation of heterocycles
@nl
P2093
P2860
P3181
P356
P1476
Innate C-H trifluoromethylation of heterocycles
@en
P2093
Donna G Blackmond
Ian B Seiple
Phil S Baran
Ryan D Baxter
Tobias Brueckl
Yuta Fujiwara
P2860
P304
P3181
P356
10.1073/PNAS.1109059108
P407
P577
2011-08-30T00:00:00Z