The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript
about
P1343
Cloning and nucleotide sequence of human gamma-glutamyl transpeptidaseA fusion protein formed by L-myc and a novel gene in SCLCThe (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34The first intron in the human c-abl gene is at least 200 kilobases long and is a target for translocations in chronic myelogenous leukemiaCan, a putative oncogene associated with myeloid leukemogenesis, may be activated by fusion of its 3' half to different genes: characterization of the set geneThe t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger proteinAssociation of HLA Class I and Class II genes with bcr-abl transcripts in leukemia patients with t(9;22) (q34;q11)Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphomaOrigin of noncoding DNA sequences: molecular fossils of genome evolutionRegulation of cell migration and survival by focal adhesion targeting of Lasp-1Molecular mechanisms of cancer.Heterogeneity of genomic fusion of BCR and ABL in Philadelphia chromosome-positive acute lymphoblastic leukemia.Diagnosis of chronic myeloid and acute lymphocytic leukemias by detection of leukemia-specific mRNA sequences amplified in vitro.Localization of preferential sites of rearrangement within the BCR gene in Philadelphia chromosome-positive acute lymphoblastic leukemiacDNA sequence for human bcr, the gene that translocates to the abl oncogene in chronic myeloid leukaemiaMolecular analysis of TCRB and ABL in a t(7;9)-containing cell line (SUP-T3) from a human T-cell leukemia.Aptameric inhibition of p210bcr-abl tyrosine kinase autophosphorylation by oligodeoxynucleotides of defined sequence and backbone structureUnique organization of the human BCR gene promoterDuplication of the bcr and gamma-glutamyl transpeptidase genesCell type dependent regulation of multidrug resistance-1 gene expression by AML1-ETO.Replication of proto-oncogenes early during the S phase in mammalian cell lines.A bcr-v-abl oncogene induces lymphomas in transgenic mice.Overlapping cDNA clones define the complete coding region for the P210c-abl gene product associated with chronic myelogenous leukemia cells containing the Philadelphia chromosome.The biological basis for immunotherapy in patients with chronic myelogenous leukemia.SHIP-mediated inhibition of K562 erythroid differentiation requires an intact catalytic domain and Shc binding site.Molecular analysis of both translocation products of a Philadelphia-positive CML patient.Elongation and maturation of c-myc RNA is inhibited by differentiation inducing agents in HL60 cells.Nucleotide sequence of both reciprocal translocation junction regions in a patient with Ph positive acute lymphoblastic leukaemia, with a breakpoint within the first intron of the BCR gene.The first BCR gene intron contains breakpoints in Philadelphia chromosome positive leukemia.Evidence that the phl gene encodes a 160,000-dalton phosphoprotein with associated kinase activityAntisense inhibition of P210 bcr-abl in chronic myeloid leukemia.Comparative genomic hybridization reveals previously undescribed amplifications and deletions in the chronic myeloid leukemia-derived K-562 cell line.Truncation does not abrogate transcriptional downregulation of the c-myc gene by sodium butyrate in Burkitt's lymphoma cells.Induction of platelet-derived growth factor gene expression during megakaryoblastic and monocytic differentiation of human leukemia cell linesComparison of different ribozymes for efficient and specific cleavage of BCR/ABL related mRNAs.Activation of class I HLA expression by TNF-alpha and gamma-interferon is mediated through protein kinase C-dependent pathway in CML cell lines.Cytogenetics of leukemia.Philadelphia chromosome-positive chronic myelogenous leukemia with deleted fusion of BCR and ABL genes.Antibody recognition of the tumor-specific bcr-abl joining region in chronic myeloid leukemia.Persistence of chronic myelocytic leukemia despite deletion of rearranged bcr/c-abl sequences in blast crisis.
P2860
Q24293948-13D2DD41-B1EE-49AF-A336-78056E21F9B4Q24317183-68D79D05-59D5-4D7C-ACAF-09E9FEC455F1Q24598594-090BFE6E-B6A9-4BB4-B3FA-E06012E146B4Q24613429-2D0D29D4-D90E-436E-AB1A-60B28F3412B8Q24629998-F8406675-F3B3-4650-9285-FA7B45A87142Q24633137-97E3F7D0-BB05-4EF7-B91C-560309A52988Q24797667-504B1A3B-77F5-4FC8-A92C-949D10B2809DQ28586873-C6C1E960-A11F-437B-A766-1122B0FD5DD1Q28776553-0BCA28C6-0BCB-4C30-B843-FFEA23490D80Q30164085-E8D751E6-A80A-415C-AC32-B03C13C1A029Q30498610-C6B50263-1430-49A5-B72E-A3D5C563127DQ33567838-965974F6-167A-4F40-B9E0-339756188FFAQ33636924-CB1A7989-9DA3-44F8-8699-285FFF23F24AQ33867942-BCAD886F-D1C5-44F1-ADE1-052BB1B1F5E4Q33928743-76BB30F3-F354-4B13-B76F-BC7808251E79Q34586425-79793424-2F67-45BE-95B3-E39C17278303Q34841821-D3F17E1F-7B0B-4203-A940-2DF67D04AC28Q35892459-42820961-36B9-4CDE-A455-1FA31199C466Q36063891-04DE606F-BD42-49CB-AB4F-8F17B036CDF4Q36102812-68D00358-6D5F-42D9-809B-BEFEE1755AACQ36112844-12D589CD-1531-46B0-B08F-6D3F495B8F19Q36769035-5654AE0B-C505-45C6-AF0C-34A6163C2583Q37412857-AFE829A1-AB8D-4E30-B7EB-B322CA429376Q37428671-F4AAF204-5B5A-4B43-AC4A-6E078A4E2603Q38317552-1F8C8AAB-F549-40BA-8A5A-C4427DBEEBDCQ40418479-7A778435-DCFE-4C58-858E-5463C44CD203Q40514722-D52E44CF-E6D0-47BD-A3C7-C9B49C849115Q40520345-26DD32D8-20DB-444D-A747-46513B61C168Q40556706-DAD1765F-DD72-449D-8344-3145DB47E41EQ40659361-0BD09208-FBF8-4D81-BBA2-D559335D49EEQ40809650-43559E33-EBBF-4098-98A0-8306223C3C45Q41114185-4FAEF249-4DE6-45BE-ABF5-907163088A41Q41349782-C8E77C6A-C078-4E75-BC26-E83B36D5FBE9Q41362063-608CCE33-3452-4AD9-8B48-BC2EF584D5BBQ41493198-2AAB2511-C6DB-4EB9-93EC-990C65316089Q41676512-BFBCC716-6C8A-40AE-9075-70E7DCF39CECQ41725789-DD7876BF-04EA-4366-9BE5-89B76787F64CQ41788178-26F1B596-B8D2-4E48-BC1D-C0BB88445820Q41925041-2930EFAC-7292-4C19-A6DC-05BAE225E61AQ42938570-6875C007-12DE-4A19-9F67-DFAD9E8AB3D6
P2860
The chronic myelocytic cell line K562 contains a breakpoint in bcr and produces a chimeric bcr/c-abl transcript
description
1986 nî lūn-bûn
@nan
1986 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1986年の論文
@ja
1986年論文
@yue
1986年論文
@zh-hant
1986年論文
@zh-hk
1986年論文
@zh-mo
1986年論文
@zh-tw
1986年论文
@wuu
name
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@ast
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@en
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@nl
type
label
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@ast
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@en
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@nl
prefLabel
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@ast
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@en
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@nl
P2093
P2860
P356
P1476
The chronic myelocytic cell li ...... chimeric bcr/c-abl transcript
@en
P2093
A de Klein
G Grosveld
K L Ramachandran
N Heisterkamp
T Verwoerd
T van Agthoven
P2860
P304
P356
10.1128/MCB.6.2.607
P407
P4510
P577
1986-02-01T00:00:00Z