A bcr-v-abl oncogene induces lymphomas in transgenic mice.
about
The (6;9) chromosome translocation, associated with a specific subtype of acute nonlymphocytic leukemia, leads to aberrant transcription of a target gene on 9q34Modeling of Chronic Myeloid Leukemia: An Overview of In Vivo Murine and Human Xenograft ModelsThe expression of the non-receptor tyrosine kinases Arg and c-abl is differently modulated in B lymphoid cells at different stages of differentiationTransgenic models of lymphoid neoplasia and development of a pan-hematopoietic vectorBcr-Abl with an SH3 deletion retains the ability To induce a myeloproliferative disease in mice, yet c-Abl activated by an SH3 deletion induces only lymphoid malignancyInduction of a chronic myelogenous leukemia-like syndrome in mice with v-abl and BCR/ABL.Biological consequences of the BCR/ABL fusion gene in humans and miceAn E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene.bcr-abl, the hallmark of chronic myeloid leukaemia in man, induces multiple haemopoietic neoplasms in mice.Models of chronic myeloid leukemia.Recent advances in the molecular and cellular biology of chronic myeloid leukaemia: lessons to be learned from the laboratory.Modeling Philadelphia chromosome positive leukemias.Philadelphia-positive leukemia: a personal perspective.A novel mouse model identifies cooperating mutations and therapeutic targets critical for chronic myeloid leukemia progression.BCR-ABL and v-abl oncogenes induce distinct patterns of thymic lymphoma involving different lymphocyte subsets.Differences in oncogenic potency but not target cell specificity distinguish the two forms of the BCR/ABL oncogeneA viral long terminal repeat expressed in CD4+CD8+ precursors is downregulated in mature peripheral CD4-CD8+ or CD4+CD8- T cells.Molecular analysis of the Philadelphia chromosome.The history of myeloproliferative disorders: before and after Dameshek.Hematologic disease induced in BALB/c mice by a bcr-abl retrovirus is influenced by the infection conditions.Emerging stem cell concepts for imatinib-resistant chronic myeloid leukaemia: implications for the biology, management, and therapy of the disease.Blast crisis in a murine model of chronic myelogenous leukemia.An overview of chronic myeloid leukemia and its animal models.Subcellular localization of Bcr, Abl, and Bcr-Abl proteins in normal and leukemic cells and correlation of expression with myeloid differentiation.Philadelphia chromosome-positive acute lymphoblastic leukemia- current concepts and future perspectives.Nonmyristoylated Abl proteins transform a factor-dependent hematopoietic cell line.CML: mechanisms of disease initiation and progression.Animal models of BCR/ABL-induced leukemias.Induction of erythroid differentiation by 5-fluorouracil in K562 leukemia cells.Transfection of the bcr/abl oncogene into factor-dependent cells by electroporation: acquisition of autonomous proliferation.Preferential development of pre-B lymphomas with drastically down-regulated N-myc in the E mu-ret transgenic mice.Polarized distribution of Bcr-Abl in migrating myeloid cells and co-localization of Bcr-Abl and its target proteins.Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells.Animal models for the study of childhood leukemia: considerations for model identification and optimization to identify potential risk factors.Moloney virus induction of T-cell lymphomas in a plasmacytomagenic strain of E mu-v-abl transgenic mice.Impact of Chromosomal Rearrangement upon DNA Methylation Patterns in Leukemia.New Mouse Models to Investigate the Efficacy of Drug Combinations in Human Chronic Myeloid Leukemia.Analysis ofBCR-ABL mRNA in chronic myelogenous leukemia patients and identification of a newBCR-related sequence in human DNA
P2860
Q24598594-08297F7A-B097-4E51-A618-4BB6F94103A8Q28076328-5C129258-AB04-4B06-AAD5-E7A789722327Q28200889-3E29B7F0-4236-4A87-834F-358429E4F680Q28592731-5600B00F-FDBD-4796-B6BC-D945781903E6Q30175351-8540D0E1-29CA-4D11-9094-3BAD002E4A56Q33764518-0CD9AE2C-4C73-4FC4-807C-871D2281BEE1Q33837337-446A8219-09C0-4D1B-A63C-5AB4F4870085Q33918573-75B99B19-4CF1-4907-BA35-44938598EADAQ33919315-05E7A9CA-438E-4E2B-8F80-57376517CC26Q34214855-669E7285-0749-40BF-B375-02901F2E70E1Q34235845-CA91E7DC-5EAB-4D69-B0A2-B8DA7AC0EC8BQ34405446-92A9E012-E6AF-4AFF-BB4C-2C6FDB266DACQ35022502-AA41638D-B6B0-485F-9556-52B721D7F52EQ36080675-0CFE474A-BFC4-48D6-8D16-770D5D152FC5Q36653547-E9EF9AB9-0BD4-470A-A046-EF3BA47F3C6EQ36732643-EE8ACD5D-10DD-4E7A-A7F5-555B523F90FDQ36821516-387A1114-AFDB-4AEF-A602-41662B6ABD03Q36890482-BD4D1182-F4F1-4E18-8E6D-FA52EBE80D78Q36946585-827DD089-EEE4-427B-86CA-076F6A74A4CDQ36965464-95FE0BCB-608C-415C-ADF2-05386401AB7FQ37186806-C7CFA8A4-7F54-4B35-9FA1-F633BD953840Q37646371-BFA4E53A-3547-46DD-8571-F3122ACFF933Q38637889-0C80843E-5CAE-4600-B657-A75A921483A5Q40305409-46436657-079D-439D-9E47-66C25C2B7E0AQ40637657-A1168483-1E96-4BCA-A267-E428FF0C1AEFQ40678630-9A6B7513-87E8-49A2-A168-721E155467C7Q40785980-1399953F-6F6D-4255-BBEF-2E00DB454C01Q40785985-A4D88248-C5C7-4284-802C-AEF6AD7A9AC8Q41292277-F6E5C309-D54E-4ED0-8865-3FFA6398E9E7Q41484194-6AE2CC55-B7AD-43D3-A401-CEC85FCE7C6CQ41671471-8F2F5497-0A41-4D8D-B30F-C97EA301BE3CQ42819449-B92B85A3-786F-4B0B-A345-7EAE5043B505Q43847051-4167E92D-52E2-496A-83B9-F6457670570BQ44152063-317CDCFC-0EE0-4D4A-8BE8-CDF130F72012Q45774472-5AA3A8B4-7333-451E-A003-51D3A3B04027Q52761621-C85808D6-634C-4A61-A57E-7AD71BE0F0A3Q55016655-394736D1-A876-49E3-9AD0-D1F232676F54Q58041874-4F853680-DBC3-4BA1-A8EC-6B112BAA276B
P2860
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
description
1989 nî lūn-bûn
@nan
1989年の論文
@ja
1989年論文
@yue
1989年論文
@zh-hant
1989年論文
@zh-hk
1989年論文
@zh-mo
1989年論文
@zh-tw
1989年论文
@wuu
1989年论文
@zh
1989年论文
@zh-cn
name
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
@ast
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
@en
type
label
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
@ast
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
@en
prefLabel
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
@ast
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
@en
P2093
P2860
P356
P1476
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
@en
P2093
P2860
P304
P356
10.1128/MCB.9.7.2798
P407
P577
1989-07-01T00:00:00Z