The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
about
Activating mutations in RRAS underlie a phenotype within the RASopathy spectrum and contribute to leukaemogenesisSCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myelomaThe Quest for Targets Executing MYC-Dependent Cell TransformationThe value of genomics in dissecting the RAS-network and in guiding therapeutics for RAS-driven cancersMEK and PI3K inhibition in solid tumors: rationale and evidence to dateEmerging targeted therapies for melanoma treatment (review)Ten things you should know about protein kinases: IUPHAR Review 14Reviewing the Effects of L-Leucine Supplementation in the Regulation of Food Intake, Energy Balance, and Glucose HomeostasisNuclear PI3K signaling in cell growth and tumorigenesisPI3K-AKT-mTOR-signaling and beyond: the complex network in gastroenteropancreatic neuroendocrine neoplasmsPhosphoregulation of the WAVE regulatory complex and signal integrationmTOR Signaling in Protein Translation Regulation: Implications in Cancer Genesis and Therapeutic InterventionsWill kinase inhibitors make it as glioblastoma drugs?Killing me softly--future challenges in apoptosis researchPathological and molecular advances in pediatric low-grade astrocytomaNutrient regulation of the mTOR complex 1 signaling pathwayThe circadian clock coordinates ribosome biogenesisERK reinforces actin polymerization to power persistent edge protrusion during motility.Chemoresistance and targeted therapies in ovarian and endometrial cancersEndometrial Carcinoma: Role of Current and Emerging Biomarkers in Resolving Persistent Clinical DilemmasEpidermal growth factor receptor immunohistochemistry: new opportunities in metastatic colorectal cancerAlternative signaling pathways as potential therapeutic targets for overcoming EGFR and c-Met inhibitor resistance in non-small cell lung cancerCancer Associated Fibroblast-Derived Hepatocyte Growth Factor Inhibits the Paclitaxel-Induced Apoptosis of Lung Cancer A549 Cells by Up-Regulating the PI3K/Akt and GRP78 Signaling on a Microfluidic PlatformBufalin Reverses Resistance to Sorafenib by Inhibiting Akt Activation in Hepatocellular Carcinoma: The Role of Endoplasmic Reticulum StressPTEN signaling through RAF1 proto-oncogene serine/threonine kinase (RAF1)/ERK in the epididymis is essential for male fertility.Pten loss promotes MAPK pathway dependency in HER2/neu breast carcinomasERK-mediated NF-κB activation through ASIC1 in response to acidosisCell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cellsImage-based compound profiling reveals a dual inhibitor of tyrosine kinase and microtubule polymerizationAberrant neuronal activity-induced signaling and gene expression in a mouse model of RASopathy.The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis.Knowledge-Based Analysis for Detecting Key Signaling Events from Time-Series Phosphoproteomics Data.Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation.Activity of distinct growth factor receptor network components in breast tumors uncovers two biologically relevant subtypesPI3K pathway mutations are associated with longer time to local progression after radioembolization of colorectal liver metastases.Negative regulation of ERK1/2 by PI3K is required for the protective effects of Pyropia yezoensis peptide against perfluorooctane sulfonate-induced endoplasmic reticulum stress.AKT facilitates EGFR trafficking and degradation by phosphorylating and activating PIKfyveBIIB021, an Hsp90 inhibitor, effectively kills a myelodysplastic syndrome cell line via the activation of caspases and inhibition of PI3K/Akt and NF-κB pathway proteins.Identifying novel genes and biological processes relevant to the development of cancer therapy-induced mucositis: An informative gene network analysis.MAF mediates crosstalk between Ras-MAPK and mTOR signaling in NF1.
P2860
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P2860
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年学术文章
@wuu
2011年学术文章
@zh-cn
2011年学术文章
@zh-hans
2011年学术文章
@zh-my
2011年学术文章
@zh-sg
2011年學術文章
@yue
name
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@ast
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@en
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@nl
type
label
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@ast
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@en
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@nl
prefLabel
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@ast
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@en
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@nl
P2093
P2860
P3181
P1476
The Ras-ERK and PI3K-mTOR pathways: cross-talk and compensation
@en
P2093
E Emrah Er
John Blenis
Michelle C Mendoza
P2860
P3181
P356
10.1016/J.TIBS.2011.03.006
P407
P577
2011-06-01T00:00:00Z