ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation - Wikidata - awgldk - TriplyDB

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

http://www.wikidata.org/entity/Q24621754

about

A paradigm shift: Cancer therapy with peptide-based B-cell epitopes and peptide immunotherapeutics targeting multiple solid tumor types: Emerging concepts and validation of combination immunotherapy Targeting of erbB3 receptor to overcome resistance in cancer treatment At the crossroads: EGFR and PTHrP signaling in cancer-mediated diseases of bone Regulation of ERBB3/HER3 signaling in cancer Orchestration of ErbB3 signaling through heterointeractions and homointeractions.Coarse-grained molecular simulation of epidermal growth factor receptor protein tyrosine kinase multi-site self-phosphorylation ERBB3-mediated regulation of Bergmann glia proliferation in cerebellar lamination.A Raf-induced allosteric transition of KSR stimulates phosphorylation of MEK Structural Analysis of the Mechanism of Inhibition and Allosteric Activation of the Kinase Domain of HER2 Protein A Conserved Non-canonical Motif in the Pseudoactive Site of the ROP5 Pseudokinase Domain Mediates Its Effect on Toxoplasma Virulence Crystal structures of the JAK2 pseudokinase domain and the pathogenic mutant V617F Modulation of Activation-Loop Phosphorylation by JAK Inhibitors Is Binding Mode Dependent An ATP-Competitive Inhibitor Modulates the Allosteric Function of the HER3 Pseudokinase Crystal structure of a BRAF kinase domain monomer explains basis for allosteric regulation Domain-Swapping Switch Point in Ste20 Protein Kinase SPAK ErbB polymorphisms: insights and implications for response to targeted cancer therapeutics Biochemistry. KSR plays CRAF-ty Neuregulin-1 signalling and antipsychotic treatment: potential therapeutic targets in a schizophrenia candidate signalling pathway Integrin-linked kinase is a functional Mn2+-dependent protein kinase that regulates glycogen synthase kinase-3β (GSK-3beta) phosphorylation The Tribbles 2 (TRB2) pseudokinase binds to ATP and autophosphorylates in a metal-independent manner Structure-based network analysis of activation mechanisms in the ErbB family of receptor tyrosine kinases: the regulatory spine residues are global mediators of structural stability and allosteric interactions.Pseudokinases: update on their functions and evaluation as new drug targets.Computational delineation of tyrosyl-substrate recognition and catalytic landscapes by the epidermal growth factor receptor tyrosine kinase domain.ERBB receptors: from oncogene discovery to basic science to mechanism-based cancer therapeutics.A comprehensive review of the preclinical efficacy profile of the ErbB family blocker afatinib in cancer.Structure of Fam20A reveals a pseudokinase featuring a unique disulfide pattern and inverted ATP-binding Engineered Multivalency Enhances Affibody-Based HER3 Inhibition and Downregulation in Cancer Cells ERBB3: A potential serum biomarker for early detection and therapeutic target for devil facial tumour 1 (DFT1)Co-conserved features associated with cis regulation of ErbB tyrosine kinases.Determining Cysteines Available for Covalent Inhibition Across the Human Kinome.Pseudoscaffolds and anchoring proteins: the difference is in the details.Mechanisms of activation of receptor tyrosine kinases: monomers or dimers.Yet another "active" pseudokinase, Erb3 Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.Asp-960/Glu-961 controls the movement of the C-terminal tail of the epidermal growth factor receptor to regulate asymmetric dimer formation.ERBB3 knockdown induces cell cycle arrest and activation of Bak and Bax-dependent apoptosis in colon cancer cells.A novel protein kinase-like domain in a selenoprotein, widespread in the tree of life.Kinase-mediated quasi-dimers of EGFR Receptor tyrosine kinases with intracellular pseudokinase domains A robust methodology to subclassify pseudokinases based on their nucleotide-binding properties.

P2860

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P2860

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

http://www.wikidata.org/entity/Q24621754

description

2010 nî lūn-bûn

@nan

2010 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

@yue

2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@ast

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@en

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@nl

type

label

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@ast

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@en

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@nl

prefLabel

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@ast

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@en

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@nl

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PNAS.1002753107

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Proceedings of the National Academy of Sciences of the United States of America

P1476

ErbB3/HER3 intracellular domain is competent to bind ATP and catalyze autophosphorylation

@en

P2093

Fumin Shi

http://www.w3.org/2001/XMLSchema#string

Ravi Radhakrishnan

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Shannon E Telesco

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Yingting Liu

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P2860

An allosteric mechanism for activation of the kinase domain of epidermal growth factor receptor

Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment

Heregulin-dependent regulation of HER2/neu oncogenic signaling by heterodimerization with HER3

Mechanism of activation and inhibition of the HER4/ErbB4 kinase

CASK Functions as a Mg2+-independent neurexin kinase

Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family: evidence for overexpression in a subset of human mammary tumors

Molecular cloning and expression of an additional epidermal growth factor receptor-related gene

Identification of c-erbB-3 binding sites for phosphatidylinositol 3'-kinase and SHC using an EGF receptor/c-erbB-3 chimera

Escape from HER-family tyrosine kinase inhibitor therapy by the kinase-inactive HER3

Crystallography & NMR System: A New Software Suite for Macromolecular Structure Determination

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10.1073/PNAS.1002753107

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17

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107

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20351256

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2867849

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