Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.
about
Structural specializations of α(4)β(7), an integrin that mediates rolling adhesionEnhanced dimerization drives ligand-independent activity of mutant epidermal growth factor receptor in lung cancerOrchestration of ErbB3 signaling through heterointeractions and homointeractions.Conformational Changes in the Epidermal Growth Factor Receptor: Role of the Transmembrane Domain Investigated by Coarse-Grained MetaDynamics Free Energy CalculationsErlotinib binds both inactive and active conformations of the EGFR tyrosine kinase domainStructure of the Discoidin Domain Receptor 1 Extracellular Region Bound to an Inhibitory Fab Fragment Reveals Features Important for SignalingMembrane interaction of bound ligands contributes to the negative binding cooperativity of the EGF receptorOptimal Bicelle Size q for Solution NMR Studies of the Protein Transmembrane PartitionNormal activation of discoidin domain receptor 1 mutants with disulfide cross-links, insertions, or deletions in the extracellular juxtamembrane region: mechanistic implicationsComplex relationship between ligand binding and dimerization in the epidermal growth factor receptor.Ligand binding and dynamics of the monomeric epidermal growth factor receptor ectodomain.Collagen recognition and transmembrane signalling by discoidin domain receptorsN-Glycosylation as determinant of epidermal growth factor receptor conformation in membranes.A structural perspective on the regulation of the epidermal growth factor receptor.Extracellular complexes of the hematopoietic human and mouse CSF-1 receptor are driven by common assembly principles.Ligand regulation of a constitutively dimeric EGF receptor.Structural analysis of the EGFR/HER3 heterodimer reveals the molecular basis for activating HER3 mutationsAnalysis of the Role of the C-Terminal Tail in the Regulation of the Epidermal Growth Factor ReceptorDifferential sensitivity of glioma- versus lung cancer-specific EGFR mutations to EGFR kinase inhibitorsMechanisms for kinase-mediated dimerization of the epidermal growth factor receptor.Structural Basis and Functional Role of Intramembrane Trimerization of the Fas/CD95 Death Receptor.Linker regions and flexibility around the metalloprotease domain account for conformational activation of ADAMTS-13.Architecture and membrane interactions of the EGF receptor.Exploring higher-order EGFR oligomerisation and phosphorylation--a combined experimental and theoretical approach.Relating conformation to function in integrin α5β1.Dynamic transition states of ErbB1 phosphorylation predicted by spatial stochastic modelingThe Dipole Potential Modifies the Clustering and Ligand Binding Affinity of ErbB Proteins and Their Signaling Efficiency.Structure, domain organization, and different conformational states of stem cell factor-induced intact KIT dimers.Expression of recombinant glycoproteins in mammalian cells: towards an integrative approach to structural biology.The EGFR family: not so prototypical receptor tyrosine kinases.Catalytic mechanisms and regulation of protein kinases.Putting together structures of epidermal growth factor receptorsChemical synthesis of transmembrane peptide and its application for research on the transmembrane-juxtamembrane region of membrane protein.Studying the Conformation of a Receptor Tyrosine Kinase in Solution by Inhibitor-Based Spin Labeling.Structure of the transmembrane domain of HIV-1 envelope glycoprotein.Piecing it together: Unraveling the elusive structure-function relationship in single-pass membrane receptors.Recombinant expression in E. coli of human FGFR2 with its transmembrane and extracellular domains.The juxtamembrane regions of human receptor tyrosine kinases exhibit conserved interaction sites with anionic lipids.Bipartite tetracysteine display reveals allosteric control of ligand-specific EGFR activation.The free energy landscape in translational science: how can somatic mutations result in constitutive oncogenic activation?
P2860
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P2860
Simultaneous visualization of the extracellular and cytoplasmic domains of the epidermal growth factor receptor.
description
2011 nî lūn-bûn
@nan
2011 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Simultaneous visualization of ...... dermal growth factor receptor.
@ast
Simultaneous visualization of ...... dermal growth factor receptor.
@en
type
label
Simultaneous visualization of ...... dermal growth factor receptor.
@ast
Simultaneous visualization of ...... dermal growth factor receptor.
@en
prefLabel
Simultaneous visualization of ...... dermal growth factor receptor.
@ast
Simultaneous visualization of ...... dermal growth factor receptor.
@en
P2093
P2860
P356
P1476
Simultaneous visualization of ...... dermal growth factor receptor.
@en
P2093
Noritaka Nishida
Thomas Walz
Timothy A Springer
P2860
P2888
P304
P356
10.1038/NSMB.2092
P577
2011-08-07T00:00:00Z
P5875
P6179
1029963012