Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity - Wikidata - awgldk - TriplyDB

Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity

Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity

http://www.wikidata.org/entity/Q24624288

about

Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair Involvement of DNA ligase III and ribonuclease H1 in mitochondrial DNA replication in cultured human cells DNA ligase III: a spotty presence in eukaryotes, but an essential function where tested DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair Eukaryotic DNA ligases: structural and functional insights Two DNA-binding and nick recognition modules in human DNA ligase III The maintenance of mitochondrial DNA integrity--critical analysis and update Repair of persistent strand breaks in the mitochondrial genome Mitochondrial localization of PARP-1 requires interaction with mitofilin and is involved in the maintenance of mitochondrial DNA integrity DNA base excision repair activities and pathway function in mitochondrial and cellular lysates from cells lacking mitochondrial DNA.Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance.Structure and function of the DNA ligases encoded by the mammalian LIG3 gene.DNA ligases as therapeutic targets Targeting abnormal DNA double strand break repair in cancer Mitochondrial DNA polymerase-gamma and human disease.Alcohol and mitochondria: a dysfunctional relationship Animal models of mitochondrial DNA transactions in disease and ageing Disconnecting XRCC1 and DNA ligase III Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining Mitochondrial DNA damage and repair in neurodegenerative disorders.Intra- and inter-molecular recombination of mitochondrial DNA after in vivo induction of multiple double-strand breaks.HMGA1 levels influence mitochondrial function and mitochondrial DNA repair efficiency Single-Nucleotide Polymorphisms of Genes Involved in Repair of Oxidative DNA Damage and the Risk of Recurrent Depressive Disorder.Mitochondrial DNA maintenance: an appraisal.Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells Lysine Methyltransferase SETD7 (SET7/9) Regulates ROS Signaling through mitochondria and NFE2L2/ARE pathway A novel interaction between DNA ligase III and DNA polymerase gamma plays an essential role in mitochondrial DNA stability.Two forms of mitochondrial DNA ligase III are produced in Xenopus laevis oocytes.Repair of DNA double-strand breaks by mammalian alternative end-joining pathways.

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P2860

Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity

http://www.wikidata.org/entity/Q24624288

description

2001 nî lūn-bûn

@nan

2001 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2001 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2001年の論文

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2001年論文

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2001年論文

@zh-hant

2001年論文

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2001年論文

@zh-mo

2001年論文

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2001年论文

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name

Antisense-mediated decrease in ...... ed mitochondrial DNA integrity

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Antisense-mediated decrease in ...... ed mitochondrial DNA integrity

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Antisense-mediated decrease in ...... ed mitochondrial DNA integrity

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type

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Antisense-mediated decrease in ...... ed mitochondrial DNA integrity

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Nucleic Acids Research

P1476

Antisense-mediated decrease in ...... ed mitochondrial DNA integrity

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P2093

C Campbell

http://www.w3.org/2001/XMLSchema#string

U Lakshmipathy

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P2860

DNA ligase IV is essential for V(D)J recombination and DNA double-strand break repair in human precursor lymphocytes

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

Mammalian DNA ligase III: molecular cloning, chromosomal localization, and expression in spermatocytes undergoing meiotic recombination

Reconstitution of DNA base excision-repair with purified human proteins: interaction between DNA polymerase beta and the XRCC1 protein

Genomic sequencing

A newly identified DNA ligase of Saccharomyces cerevisiae involved in RAD52-independent repair of DNA double-strand breaks

An interaction between the mammalian DNA repair protein XRCC1 and DNA ligase III

Normal oxidative damage to mitochondrial and nuclear DNA is extensive

Molecular cloning and expression of human cDNAs encoding a novel DNA ligase IV and DNA ligase III, an enzyme active in DNA repair and recombination

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

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668-76

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10.1093/NAR/29.3.668

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P407

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3

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29

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12168694

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11160888

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P921

mitochondrial DNA

P932

30390

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