Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance. - Wikidata - awgldk - TriplyDB

Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance.

Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance.

http://www.wikidata.org/entity/Q34359723

about

Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair Mitochondrial DNA: A disposable genome?Mitochondrial DNA damage induced autophagy, cell death, and disease Control of mitochondrial integrity in ageing and disease The "fast" and the "slow" modes of mitochondrial DNA degradation.A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions.Human DNA ligase III bridges two DNA ends to promote specific intermolecular DNA end joining Presequence-Independent Mitochondrial Import of DNA Ligase Facilitates Establishment of Cell Lines with Reduced mtDNA Copy Number Methods for Efficient Elimination of Mitochondrial DNA from Cultured Cells Inhibiting Mitochondrial DNA Ligase IIIα Activates Caspase 1-Dependent Apoptosis in Cancer Cells Structures of DNA-bound human ligase IV catalytic core reveal insights into substrate binding and catalysis.

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Mitochondrial DNA ligase is dispensable for the viability of cultured cells but essential for mtDNA maintenance.

http://www.wikidata.org/entity/Q34359723

description

2013 nî lūn-bûn

@nan

2013 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2013 թվականի հուլիսին հրատարակված գիտական հոդված

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2013年の論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年論文

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2013年论文

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name

Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

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Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

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Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

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Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

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Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

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Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

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Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

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JBC.M113.472977

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Journal of Biological Chemistry

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Mitochondrial DNA ligase is di ...... sential for mtDNA maintenance.

@en

P2093

Glenn L Wilson

http://www.w3.org/2001/XMLSchema#string

Inna N Shokolenko

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Mikhail F Alexeyev

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Peter J McKinnon

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Rafik Z Fayzulin

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Sachin Katyal

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P2860

The human DNA ligase III gene encodes nuclear and mitochondrial proteins

Crucial role for DNA ligase III in mitochondria but not in Xrcc1-dependent repair

DNA ligase III: a spotty presence in eukaryotes, but an essential function where tested

Functional redundancy between DNA ligases I and III in DNA replication in vertebrate cells

DNA ligase III is critical for mtDNA integrity but not Xrcc1-mediated nuclear DNA repair

Antisense-mediated decrease in DNA ligase III expression results in reduced mitochondrial DNA integrity

Human DNA ligase III recognizes DNA ends by dynamic switching between two DNA-bound states

How mitochondria produce reactive oxygen species

N-methylpurine DNA glycosylase overexpression increases alkylation sensitivity by rapidly removing non-toxic 7-methylguanine adducts

Sequence and organization of the human mitochondrial genome

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26594-26605

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10.1074/JBC.M113.472977

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37

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288

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23884459

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mitochondrial DNA

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3772206

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