Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release
about
Structural characterization of new deoxycytidine kinase inhibitors rationalizes the affinity-determining moieties of the moleculesRetrovolution: HIV-driven evolution of cellular genes and improvement of anticancer drug activationPotent Sensitisation of Cancer Cells to Anticancer Drugs by a Quadruple Mutant of the Human Deoxycytidine KinaseA phosphotyrosine switch for cargo sequestration at clathrin-coated buds.Deoxycytidine kinase augments ATM-Mediated DNA repair and contributes to radiation resistanceStructure-guided engineering of human thymidine kinase 2 as a positron emission tomography reporter gene for enhanced phosphorylation of non-natural thymidine analog reporter probe.Cell fate control gene therapy based on engineered variants of human deoxycytidine kinaseMechanistic studies on the synergistic cytotoxicity of the nucleoside analogs gemcitabine and clofarabine in multiple myeloma: relevance of p53 and its clinical implications.New insights into the synergism of nucleoside analogs with radiotherapySelective Phosphorylation of South and North-Cytidine and Adenosine Methanocarba-Nucleosides by Human Nucleoside and Nucleotide Kinases Correlates with Their Growth Inhibitory Effects on Cultured Cells.Protein phosphatase 2A regulates deoxycytidine kinase activity via Ser-74 dephosphorylation.ATR inhibition facilitates targeting of leukemia dependence on convergent nucleotide biosynthetic pathways.The Role of Deoxycytidine Kinase (dCK) in Radiation-Induced Cell Death.Dual protein kinase and nucleoside kinase modulators for rationally designed polypharmacology.
P2860
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P2860
Post-translational phosphorylation of serine 74 of human deoxycytidine kinase favors the enzyme adopting the open conformation making it competent for nucleoside binding and release
description
2011 nî lūn-bûn
@nan
2011 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Post-translational phosphoryla ...... nucleoside binding and release
@ast
Post-translational phosphoryla ...... nucleoside binding and release
@en
Post-translational phosphoryla ...... nucleoside binding and release
@nl
type
label
Post-translational phosphoryla ...... nucleoside binding and release
@ast
Post-translational phosphoryla ...... nucleoside binding and release
@en
Post-translational phosphoryla ...... nucleoside binding and release
@nl
altLabel
Post-Translational Phosphoryla ...... Nucleoside Binding and Release
@en
prefLabel
Post-translational phosphoryla ...... nucleoside binding and release
@ast
Post-translational phosphoryla ...... nucleoside binding and release
@en
Post-translational phosphoryla ...... nucleoside binding and release
@nl
P2093
P2860
P356
P1433
P1476
Post-translational phosphoryla ...... nucleoside binding and release
@en
P2093
Arnon Lavie
Manfred Konrad
Stephan Ort
P2860
P304
P356
10.1021/BI2001032
P407
P577
2011-03-16T00:00:00Z