4D-QSAR analysis of a set of propofol analogues: mapping binding sites for an anesthetic phenol on the GABA(A) receptor
about
Spike avalanches exhibit universal dynamics across the sleep-wake cycleA Unitary Anesthetic Binding Site at High ResolutionComparative molecular field analysis and synthetic validation of a hydroxyamide-propofol binding and functional block of neuronal voltage-dependent sodium channels.Complexation of phenolic guests by endo- and exo-hydrogen-bonded receptors.3D pharmacophore mapping using 4D QSAR analysis for the cytotoxicity of lamellarins against human hormone-dependent T47D breast cancer cellsCurcumol allosterically modulates GABA(A) receptors in a manner distinct from benzodiazepines.Robust photoregulation of GABA(A) receptors by allosteric modulation with a propofol analogue.Recognition of anesthetic barbiturates by a protein binding site: a high resolution structural analysis.Potentiating action of propofol at GABAA receptors of retinal bipolar cellsA Cysteine Substitution Probes β3H267 Interactions with Propofol and Other Potent Anesthetics in α1β3γ2L γ-Aminobutyric Acid Type A Receptorsp-(4-Azipentyl)propofol: a potent photoreactive general anesthetic derivative of propofol.Tryptophan mutations at azi-etomidate photo-incorporation sites on alpha1 or beta2 subunits enhance GABAA receptor gating and reduce etomidate modulation.Role for the propofol hydroxyl in anesthetic protein target molecular recognition.A Novel Bifunctional Alkylphenol Anesthetic Allows Characterization of γ-Aminobutyric Acid, Type A (GABAA), Receptor Subunit Binding Selectivity in Synaptosomes.Assessment of homology templates and an anesthetic binding site within the γ-aminobutyric acid receptor.The discovery of new anesthetics by targeting GABA(A) receptors.Quantitative structure-activity relationship: promising advances in drug discovery platforms.A receptor dependent-4D QSAR approach to predict the activity of mutated enzymes.The great descriptor melting pot: mixing descriptors for the common good of QSAR models.Long-term action of propofol on cognitive function and hippocampal neuroapoptosis in neonatal rats.The comparison of preemptive effects of propofol, remifentanil and ketamine on post-operative pain scores and analgesic requirements in elective lower abdominal surgery under general anesthesia: A randomized, double-blinded studyContradicting a unitary theory of general anesthetic action: a history of three compounds from 1901 to 2001.Impact of malnutrition on propofol consumption and recovery time among patients undergoing laparoscopic gastrointestinal surgery.Quantitative bioactivity prediction and pharmacophore identification for benzotriazine derivatives using the electron conformational-genetic algorithm in QSAR.Quantitative structure-activity relationships of monoterpenoid binding activities to the housefly GABA receptor.
P2860
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P2860
4D-QSAR analysis of a set of propofol analogues: mapping binding sites for an anesthetic phenol on the GABA(A) receptor
description
2002 nî lūn-bûn
@nan
2002 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2002年の論文
@ja
2002年論文
@yue
2002年論文
@zh-hant
2002年論文
@zh-hk
2002年論文
@zh-mo
2002年論文
@zh-tw
2002年论文
@wuu
name
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@ast
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@en
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@nl
type
label
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@ast
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@en
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@nl
prefLabel
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@ast
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@en
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@nl
P2093
P2860
P3181
P356
P1476
4D-QSAR analysis of a set of p ...... phenol on the GABA(A) receptor
@en
P2093
A J Hopfinger
Neil L Harrison
P2860
P304
P3181
P356
10.1021/JM010461A
P407
P577
2002-07-18T00:00:00Z