Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways
about
Ligand binding to WW tandem domains of YAP2 transcriptional regulator is under negative cooperativityRegulating the Regulators: Recent Revelations in the Control of E3 Ubiquitin LigasesEvidence for small-molecule-mediated loop stabilization in the structure of the isolated Pin1 WW domainVersatile communication strategies among tandem WW domain repeatsHeterozygous loss-of-function mutations in YAP1 cause both isolated and syndromic optic fissure closure defectsUSP15 regulates SMURF2 kinetics through C-lobe mediated deubiquitination.Regulation of Ubiquitin Enzymes in the TGF-β Pathway.USP26 regulates TGF-β signaling by deubiquitinating and stabilizing SMAD7New gene evolution in the bonus-TIF1-γ/TRIM33 family impacted the architecture of the vertebrate dorsal-ventral patterning network.RNA recognition and self-association of CPEB4 is mediated by its tandem RRM domains.WWOX at the crossroads of cancer, metabolic syndrome related traits and CNS pathologies.Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.AKT regulation of mesothelial-to-mesenchymal transition in peritoneal dialysis is modulated by Smurf2 and deubiquitinating enzyme USP4Structure of the N-terminal domain of the protein Expansion: an 'Expansion' to the Smad MH2 fold.WW domains of the yes-kinase-associated-protein (YAP) transcriptional regulator behave as independent units with different binding preferences for PPxY motif-containing ligands.Yes-associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells.Association of colorectal cancer susceptibility variants with esophageal cancer in a Chinese populationSmad7 Protein Interacts with Receptor-regulated Smads (R-Smads) to Inhibit Transforming Growth Factor-β (TGF-β)/Smad Signaling.The Hippo signal transduction network for exercise physiologistsThe Smad7-Skp2 complex orchestrates Myc stability, impacting on the cytostatic effect of TGF-βMolecular basis of the binding of YAP transcriptional regulator to the ErbB4 receptor tyrosine kinase.The Hippo signal transduction network in skeletal and cardiac muscle.Structural dissection of Hippo signaling.Genome-wide analysis of the WW domain-containing protein genes in silkworm and their expansion in eukaryotes.Structural determinants of Smad function in TGF-β signaling.Global analysis of protein folding using massively parallel design, synthesis, and testing.Interactions of U24 from Roseolovirus with WW domains: canonical vs noncanonical.Structural insights into the catalysis and regulation of E3 ubiquitin ligases.The effects of WW2/WW3 domains of Smurf2 molecule on TGF-β signaling and arginase I gene expression.Structural Basis of Intracellular TGF-β Signaling: Receptors and Smads.U24 from Roseolovirus interacts strongly with Nedd4 WW Domains.Tumor suppressor WWOX binds to ΔNp63α and sensitizes cancer cells to chemotherapySAV1 promotes Hippo kinase activation through antagonizing the PP2A phosphatase STRIPAK.Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.Biophysical studies and NMR structure of YAP2 WW domain - LATS1 PPxY motif complexes reveal the basis of their interaction.YAP/TAZ regulates TGF-β/Smad3 signaling by induction of Smad7 via AP-1 in human skin dermal fibroblasts.
P2860
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P2860
Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways
description
2012 nî lūn-bûn
@nan
2012 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@ast
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@en
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@nl
type
label
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@ast
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@en
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@nl
altLabel
Structural Basis for the Versa ...... r WW Domains in TGF-β Pathways
@en
prefLabel
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@ast
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@en
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@nl
P2093
P2860
P50
P1433
P1476
Structural basis for the versa ...... r WW domains in TGF-β Pathways
@en
P2093
Nina Goerner
Qiaoran Xi
P2860
P304
P356
10.1016/J.STR.2012.07.014
P407
P5008
P577
2012-08-23T00:00:00Z