Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

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Targeting HECT-type E3 ligases - insights from catalysis, regulation and inhibitors.Substrate clustering potently regulates activity of WW-HECT domain-containing ubiquitin ligases.A Tyrosine Switch on NEDD4-2 E3 Ligase Transmits GPCR Inflammatory Signaling

P2860

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P2860

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

Item

http://www.wikidata.org/entity/Q48178072

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2017 nî lūn-bûn

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2017年の論文

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2017年学术文章

@wuu

2017年学术文章

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2017年学术文章

@zh-hans

2017年学术文章

@zh-my

2017年学术文章

@zh-sg

2017年學術文章

@yue

2017年學術文章

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2017年學術文章

@zh-hant

name

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

@en

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

@nl

type

Item

label

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

@en

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

@nl

prefLabel

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

@en

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

@nl

P1476

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch

@en

P2093

Changlin Tian

http://www.w3.org/2001/XMLSchema#string

Jizhong Lou

http://www.w3.org/2001/XMLSchema#string

Kang Zhu

http://www.w3.org/2001/XMLSchema#string

Lei Cui

http://www.w3.org/2001/XMLSchema#string

Pan Shi

http://www.w3.org/2001/XMLSchema#string

Weiyi Yao

http://www.w3.org/2001/XMLSchema#string

Xing Chen

http://www.w3.org/2001/XMLSchema#string

Yunli Xie

http://www.w3.org/2001/XMLSchema#string

Yuqun Cai

http://www.w3.org/2001/XMLSchema#string

Zelin Shan

http://www.w3.org/2001/XMLSchema#string

P2860

Recognition and ubiquitination of Notch by Itch, a hect-type E3 ubiquitin ligase

Conformational flexibility underlies ubiquitin ligation mediated by the WWP1 HECT domain E3 ligase

The ubiquitin-protein ligase Itch regulates p73 stability

The itchy locus encodes a novel ubiquitin protein ligase that is disrupted in a18H mice

Atrophin-1, the DRPLA gene product, interacts with two families of WW domain-containing proteins

Autoinhibition of the HECT-type ubiquitin ligase Smurf2 through its C2 domain

Calcium activates Nedd4 E3 ubiquitin ligases by releasing the C2 domain-mediated auto-inhibition

Structural basis for the versatile interactions of Smad7 with regulator WW domains in TGF-β Pathways

Control of the activity of WW-HECT domain E3 ubiquitin ligases by NDFIP proteins

PHENIX: a comprehensive Python-based system for macromolecular structure solution

P304

1618-1630

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scholarly article

P356

10.15252/EMBR.201744454

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P433

http://www.w3.org/2001/XMLSchema#string

P478

http://www.w3.org/2001/XMLSchema#string

P50

Wenyu Wen

P577

2017-07-26T00:00:00Z

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P698

28747490

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P932

5579370

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Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

about

P2860

P2860

Allosteric auto-inhibition and activation of the Nedd4 family E3 ligase Itch.

description

name

type

label

prefLabel

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932

P356

P1433

P1476

P2093

P2860

P304

P31

P356

P433

P478

P50

P577

P698

P932