XRCC4's interaction with XLF is required for coding (but not signal) end joining - Wikidata - awgldk - TriplyDB

XRCC4's interaction with XLF is required for coding (but not signal) end joining

XRCC4's interaction with XLF is required for coding (but not signal) end joining

http://www.wikidata.org/entity/Q24630098

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DNA ligase III and DNA ligase IV carry out genetically distinct forms of end joining in human somatic cells A human XRCC4-XLF complex bridges DNA Role of non-homologous end joining in V(D)J recombination The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.A noncatalytic function of the ligation complex during nonhomologous end joining.Nonhomologous end joining: a good solution for bad ends Structural and functional characterization of the PNKP-XRCC4-LigIV DNA repair complex Mutational phospho-mimicry reveals a regulatory role for the XRCC4 and XLF C-terminal tails in modulating DNA bridging during classical non-homologous end joining The C-terminus of Nej1 is critical for nuclear localization and non-homologous end-joining.DNA Ligase IV regulates XRCC4 nuclear localization.XRCC4 and XLF form long helical protein filaments suitable for DNA end protection and alignment to facilitate DNA double strand break repair.Yeast DNA ligase IV mutations reveal a nonhomologous end joining function of BRCT1 distinct from XRCC4/Lif1 binding.XRCC4/XLF Interaction Is Variably Required for DNA Repair and Is Not Required for Ligase IV Stimulation Transposon Invasion of the Paramecium Germline Genome Countered by a Domesticated PiggyBac Transposase and the NHEJ Pathway.RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair Restoration of ATM Expression in DNA-PKcs-Deficient Cells Inhibits Signal End Joining.Lif1 SUMOylation and its role in non-homologous end-joining.C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair Real-time analysis of RAG complex activity in V(D)J recombination A role for XLF in DNA repair and recombination in human somatic cells.Resolution of complex ends by Nonhomologous end joining - better to be lucky than good?Detection and repair of ionizing radiation-induced DNA double strand breaks: new developments in nonhomologous end joining.The spatial organization of non-homologous end joining: from bridging to end joining.Functional overlaps between XLF and the ATM-dependent DNA double strand break response.TDP1 promotes assembly of non-homologous end joining protein complexes on DNA.A nonsense mutation of human XRCC4 is associated with adult-onset progressive encephalocardiomyopathy Sliding sleeves of XRCC4-XLF bridge DNA and connect fragments of broken DNA.

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XRCC4's interaction with XLF is required for coding (but not signal) end joining

http://www.wikidata.org/entity/Q24630098

description

2012 nî lūn-bûn

@nan

2012 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2012 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2012年の論文

@ja

2012年論文

@yue

2012年論文

@zh-hant

2012年論文

@zh-hk

2012年論文

@zh-mo

2012年論文

@zh-tw

2012年论文

@wuu

name

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@ast

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@en

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@nl

type

label

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@ast

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@en

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@nl

prefLabel

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@ast

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@en

XRCC4's interaction with XLF is required for coding (but not signal) end joining

@nl

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Nucleic Acids Research

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XRCC4's interaction with XLF is required for coding (but not signal) end joining

@en

P2093

Alexandra Vergnes

http://www.w3.org/2001/XMLSchema#string

Jessica A Neal

http://www.w3.org/2001/XMLSchema#string

Katheryn Meek

http://www.w3.org/2001/XMLSchema#string

Sara N Andres

http://www.w3.org/2001/XMLSchema#string

Sunetra Roy

http://www.w3.org/2001/XMLSchema#string

Susan P Lees-Miller

http://www.w3.org/2001/XMLSchema#string

Yao Xu

http://www.w3.org/2001/XMLSchema#string

Yaping Yu

http://www.w3.org/2001/XMLSchema#string

P2860

Crystal structure of an Xrcc4-DNA ligase IV complex

Functional significance of the interaction with Ku in DNA double-strand break recognition of XLF

Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination

Cernunnos, a novel nonhomologous end-joining factor, is mutated in human immunodeficiency with microcephaly

XLF interacts with the XRCC4-DNA ligase IV complex to promote DNA nonhomologous end-joining

Ku recruits XLF to DNA double-strand breaks

DNA binding of Xrcc4 protein is associated with V(D)J recombination but not with stimulation of DNA ligase IV activity

ATM damage response and XLF repair factor are functionally redundant in joining DNA breaks

Crystal structure of the Xrcc4 DNA repair protein and implications for end joining

Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining

P304

1684-94

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scholarly article

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10.1093/NAR/GKR1315

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P407

P433

4

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P478

40

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P577

2012-02-01T00:00:00Z

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221732683

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22228831

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3287172

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