ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma - Wikidata - awgldk - TriplyDB

ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

http://www.wikidata.org/entity/Q24632451

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Identification of a functional binding site for activin on the type I receptor ALK4 Antibody blockade of the Cripto CFC domain suppresses tumor cell growth in vivo Activins and activin antagonists in hepatocellular carcinoma Activin receptor-like kinases: a diverse family playing an important role in cancer Loss of heterozygosity and mutational analyses of the ACTRII gene locus in human colorectal tumors Pancreatic cancer.Characterization of gene expression in mucinous cystic neoplasms of the pancreas using oligonucleotide microarrays.Homozygous deletion of the activin A receptor, type IB gene is associated with an aggressive cancer phenotype in pancreatic cancer Conditional activin receptor type 1B (Acvr1b) knockout mice reveal hair loss abnormality.Pancreatic cancer genomics: insights and opportunities for clinical translation Molecular signatures of pancreatic cancer.Role of myoepithelial cells in breast tumor progression.Prognostic significance and gene expression profiles of p53 mutations in microsatellite-stable stage III colorectal adenocarcinomas Genetic evolution of pancreatic cancer: lessons learnt from the pancreatic cancer genome sequencing project.A kinase shRNA screen links LATS2 and the pRB tumor suppressor Cripto forms a complex with activin and type II activin receptors and can block activin signaling Activin A balance regulates epithelial invasiveness and tumorigenesis Genomic microarrays in human genetic disease and cancer.Aberrant methylation of preproenkephalin and p16 genes in pancreatic intraepithelial neoplasia and pancreatic ductal adenocarcinoma.The deubiquitinase USP9X suppresses pancreatic ductal adenocarcinoma.Esophageal squamous cell carcinoma invasion is inhibited by Activin A in ACVRIB-positive cells.Suppression of activin A signals inhibits growth of malignant pleural mesothelioma cells.Molecular genetics of pancreatic ductal adenocarcinomas and recent implications for translational efforts.Activin a signaling regulates cell invasion and proliferation in esophageal adenocarcinoma Pancreatic carcinogenesis Activin signaling as an emerging target for therapeutic interventions Functional analysis of saxophone, the Drosophila gene encoding the BMP type I receptor ortholog of human ALK1/ACVRL1 and ACVR1/ALK2.Immortalizing the complexity of cancer metastasis: genetic features of lethal metastatic pancreatic cancer obtained from rapid autopsy.Challenges and advances in mouse modeling for human pancreatic tumorigenesis and metastasis Variants in inflammation genes are implicated in risk of lung cancer in never smokers exposed to second-hand smoke.Molecular biology of pancreatic ductal adenocarcinoma progression: aberrant activation of developmental pathways.Activin receptor antagonists for cancer-related anemia and bone disease.Frequent loss of heterozygosity on chromosome 12q in non-small-cell lung carcinomas.Prognostic value of follistatin-like 3 in human invasive breast cancer Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.Activin type 2 receptor restoration in MSI-H colon cancer suppresses growth and enhances migration with activin.Expression of SMAD proteins, TGF-beta/activin signaling mediators, in human thyroid tissues.Generation of a conditional mouse model to target Acvr1b disruption in adult tissues.Loss of ACVRIB leads to increased squamous cell carcinoma aggressiveness through alterations in cell-cell and cell-matrix adhesion proteins.Human cancer tissues exhibit reduced A-to-I editing of miRNAs coupled with elevated editing of their targets.

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

http://www.wikidata.org/entity/Q24632451

description

2001 nî lūn-bûn

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2001 թուականի Մարտին հրատարակուած գիտական յօդուած

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2001 թվականի մարտին հրատարակված գիտական հոդված

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2001年の論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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2001年論文

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

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Proceedings of the National Academy of Sciences of the United States of America

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ACVR1B (ALK4, activin receptor type 1B) gene mutations in pancreatic carcinoma

@en

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C J Yeo

http://www.w3.org/2001/XMLSchema#string

E Montgomery

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G H Su

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K M Murphy

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R Bansal

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R H Hruban

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S E Kern

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Activation of signalling by the activin receptor complex

Receptor-associated Mad homologues synergize as effectors of the TGF-beta response

Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC

Type I receptors specify growth-inhibitory and transcriptional responses to transforming growth factor beta and activin

Germline and somatic mutations of the STK11/LKB1 Peutz-Jeghers gene in pancreatic and biliary cancers

Genetic alterations of cyclins, cyclin-dependent kinases, and Cdk inhibitors in human cancer

Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma

Cancer cell cycles

DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

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10.1073/PNAS.051484398

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