RGS9-2: probing an intracellular modulator of behavior as a drug target. - Wikidata - awgldk - TriplyDB

RGS9-2: probing an intracellular modulator of behavior as a drug target.

RGS9-2: probing an intracellular modulator of behavior as a drug target.

http://www.wikidata.org/entity/Q24632848

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Type 5 G protein beta subunit (Gbeta5) controls the interaction of regulator of G protein signaling 9 (RGS9) with membrane anchors μ-Opioid receptors and regulators of G protein signaling (RGS) proteins: from a symposium on new concepts in mu-opioid pharmacology R7BP complexes with RGS9-2 and RGS7 in the striatum differentially control motor learning and locomotor responses to cocaine Emerging Putative Associations between Non-Coding RNAs and Protein-Coding Genes in Neuropathic Pain: Added Value from Reusing Microarray Data Proteomic identification of Hsc70 as a mediator of RGS9-2 degradation by in vivo interactome analysis.Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins A conserved protein interaction interface on the type 5 G protein beta subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins.Regulators of G protein signaling (RGS) proteins as drug targets: modulating G-protein-coupled receptor (GPCR) signal transduction Sensitivity and kinetics of signal transmission at the first visual synapse differentially impact visually-guided behavior.β-arrestin2 plays permissive roles in the inhibitory activities of RGS9-2 on G protein-coupled receptors by maintaining RGS9-2 in the open conformation.D(2)-Dopamine receptors target regulator of G protein signaling 9-2 to detergent-resistant membrane fractions.RGS9-2 modulates sensory and mood related symptoms of neuropathic pain.R7BP modulates opiate analgesia and tolerance but not withdrawal.RGS9-2--controlled adaptations in the striatum determine the onset of action and efficacy of antidepressants in neuropathic pain states.A unique role of RGS9-2 in the striatum as a positive or negative regulator of opiate analgesia The complex of G protein regulator RGS9-2 and Gβ(5) controls sensitization and signaling kinetics of type 5 adenylyl cyclase in the striatum Macromolecular composition dictates receptor and G protein selectivity of regulator of G protein signaling (RGS) 7 and 9-2 protein complexes in living cells.Modulation of pain, nociception, and analgesia by the brain reward center.RGS9-2 Modulates Responses to Oxycodone in Pain-Free and Chronic Pain States.Current Concepts on the Physiopathological Relevance of Dopaminergic Receptors Nucleus accumbens-specific interventions in RGS9-2 activity modulate responses to morphine.Membrane anchoring subunits specify selective regulation of RGS9·Gbeta5 GAP complex in photoreceptor neurons.Genetic Analysis of Rare Human Variants of Regulators of G Protein Signaling Proteins and Their Role in Human Physiology and Disease

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

http://www.wikidata.org/entity/Q24632848

description

2009 nî lūn-bûn

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2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

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2009年の論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年論文

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2009年论文

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name

RGS9-2: probing an intracellular modulator of behavior as a drug target

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

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type

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RGS9-2: probing an intracellular modulator of behavior as a drug target

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

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RGS9-2: probing an intracellular modulator of behavior as a drug target

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

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J.TIPS.2008.11.006

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Trends in Pharmacological Sciences

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RGS9-2: probing an intracellular modulator of behavior as a drug target.

@en

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Barbara J Caldarone

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Dimitra Terzi

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John R Traynor

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Venetia Zachariou

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P2860

Motor coordination deficits in mice lacking RGS9

Essential role for RGS9 in opiate action

Instability of GGL domain-containing RGS proteins in mice lacking the G protein beta-subunit Gbeta5

Sst2, a negative regulator of pheromone signaling in the yeast Saccharomyces cerevisiae: expression, localization, and genetic interaction and physical association with Gpa1 (the G-protein alpha subunit).

GTPase-activating proteins for heterotrimeric G proteins: regulators of G protein signaling (RGS) and RGS-like proteins

Defects in RGS9 or its anchor protein R9AP in patients with slow photoreceptor deactivation

RGS9-2 is a negative modulator of mu-opioid receptor function

A role of RGS proteins in drug addiction

Regulators of G-protein signaling (RGS) proteins: region-specific expression of nine subtypes in rat brain

Making the case for a candidate vulnerability gene in schizophrenia: Convergent evidence for regulator of G-protein signaling 4 (RGS4)

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