Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly - Wikidata - awgldk - TriplyDB

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

http://www.wikidata.org/entity/Q24632884

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The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex components Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes 5-HT(6) receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia SCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myeloma PIH1D1 interacts with mTOR complex 1 and enhances ribosome RNA transcription mTOR signaling in growth control and disease Advances in Autophagy Regulatory Mechanisms Therapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shift Tor forms a dimer through an N-terminal helical solenoid with a complex topology.The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.Judicious Toggling of mTOR Activity to Combat Insulin Resistance and Cancer: Current Evidence and Perspectives Left-right asymmetry in the light of TOR: An update on what we know so far TBCK influences cell proliferation, cell size and mTOR signaling pathway The Mechanistic Target of Rapamycin: The Grand ConducTOR of Metabolism and Aging Where is mTOR and what is it doing there?Forced expression of the DEK-NUP214 fusion protein promotes proliferation dependent on upregulation of mTOR Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2 Nutrient signaling to mTOR and cell growth.Drosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signaling Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.Transcriptome sequencing reveals potential mechanism of cryptic 3' splice site selection in SF3B1-mutated cancers Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome mTOR complex 2 signaling and functions Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).Genetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1.Bicyclol induces cell cycle arrest and autophagy in HepG2 human hepatocellular carcinoma cells through the PI3K/AKT and Ras/Raf/MEK/ERK pathways.mTORC1-independent Raptor prevents hepatic steatosis by stabilizing PHLPP2.Metabolic stress controls mTORC1 lysosomal localization and dimerization by regulating the TTT-RUVBL1/2 complex.Regulation of Ribosome Biogenesis and Protein Synthesis Controls Germline Stem Cell Differentiation Small molecule therapeutics targeting F-box proteins in cancer.mTOR and vascular remodeling in lung diseases: current challenges and therapeutic prospects.A Syndromic Intellectual Disability Disorder Caused by Variants in TELO2, a Gene Encoding a Component of the TTT Complex.ATR signalling: more than meeting at the fork.Nutrient-sensing mTORC1: Integration of metabolic and autophagic signals Mechanisms and function of substrate recruitment by F-box proteins.Hyperhomocysteinemia causes ER stress and impaired autophagy that is reversed by Vitamin B supplementation.Targeting mTOR network in colorectal cancer therapy Mammalian target of rapamycin signaling in cardiac physiology and disease.mTOR function and therapeutic targeting in breast cancer.ATM protein kinase: the linchpin of cellular defenses to stress.

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P2860

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

http://www.wikidata.org/entity/Q24632884

description

2010 nî lūn-bûn

@nan

2010 թուականի Յունիսին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի հունիսին հրատարակված գիտական հոդված

@hy

2010年の論文

@ja

2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

@zh-mo

2010年論文

@zh-tw

2010年论文

@wuu

name

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@ast

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@en

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@nl

type

label

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@ast

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@en

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@nl

prefLabel

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@ast

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@en

Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@nl

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JBC.M110.121699

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Journal of Biological Chemistry

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Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly

@en

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Kazuyoshi Yonezawa

http://www.w3.org/2001/XMLSchema#string

Kenji Takehana

http://www.w3.org/2001/XMLSchema#string

Noriko Oshiro

http://www.w3.org/2001/XMLSchema#string

Shun-Ichiro Iemura

http://www.w3.org/2001/XMLSchema#string

Taichi Hara

http://www.w3.org/2001/XMLSchema#string

Takeshi Kaizuka

http://www.w3.org/2001/XMLSchema#string

Tohru Natsume

http://www.w3.org/2001/XMLSchema#string

Ushio Kikkawa

http://www.w3.org/2001/XMLSchema#string

P2860

Rictor, a novel binding partner of mTOR, defines a rapamycin-insensitive and raptor-independent pathway that regulates the cytoskeleton

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

Tel2 regulates the stability of PI3K-related protein kinases

AAA+ proteins RUVBL1 and RUVBL2 coordinate PIKK activity and function in nonsense-mediated mRNA decay

ATMIN defines an NBS1-independent pathway of ATM signalling

Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Emerging common themes in regulation of PIKKs and PI3Ks

ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery

High-quality binary protein interaction map of the yeast interactome network

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20109-16

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scholarly article

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1647213

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10.1074/JBC.M110.121699

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P433

26

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285

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Mizushima Noboru

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2010-06-25T00:00:00Z

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43351360

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20427287

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2888423

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