Tel2 regulates the stability of PI3K-related protein kinases
about
The complete spectrum of yeast chromosome instability genes identifies candidate CIN cancer genes and functional roles for ASTRA complex componentsHERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomesTel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexesA genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stabilitySCFFbxo9 and CK2 direct the cellular response to growth factor withdrawal via Tel2/Tti1 degradation and promote survival in multiple myelomaPhosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complexTti1 and Tel2 are critical factors in mammalian target of rapamycin complex assemblySubstrate recognition and function of the R2TP complex in response to cellular stressTherapeutic targeting of cellular metabolism in cells with hyperactive mTORC1: a paradigm shiftFunctional dissection of Caenorhabditis elegans CLK-2/TEL2 cell cycle defects during embryogenesis and germline developmentTor forms a dimer through an N-terminal helical solenoid with a complex topology.The DNA Damage Response: Making It Safe to Play with KnivesTel2 mediates activation and localization of ATM/Tel1 kinase to a double-strand break.Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response.The C-terminal residues of Saccharomyces cerevisiae Mec1 are required for its localization, stability, and function.Mitochondrial ROS and the Effectors of the Intrinsic Apoptotic Pathway in Aging Cells: The Discerning Killers!The catalytic subunit of DNA-dependent protein kinase regulates proliferation, telomere length, and genomic stability in human somatic cellsWhere is mTOR and what is it doing there?ATR: an essential regulator of genome integrityA unified powerful set-based test for sequencing data analysis of GxE interactions.SUMOylation of ATRIP potentiates DNA damage signaling by boosting multiple protein interactions in the ATR pathwayThe role of the Fanconi anemia network in the response to DNA replication stress.ATR activation and replication fork restart are defective in FANCM-deficient cells.Inositol pyrophosphates mediate the DNA-PK/ATM-p53 cell death pathway by regulating CK2 phosphorylation of Tti1/Tel2Transformation/transcription domain-associated protein (TRRAP)-mediated regulation of Wee1Expression and functional roles of angiopoietin-2 in skeletal musclesLow levels of ATM in breast cancer patients with clinical radiosensitivity.Genetic and physical interactions between Tel2 and the Med15 Mediator subunit in Saccharomyces cerevisiae.Nutrient signaling to mTOR and cell growth.Regulatory roles of tankyrase 1 at telomeres and in DNA repair: suppression of T-SCE and stabilization of DNA-PKcs.Drosophila Tel2 is expressed as a translational fusion with EpsinR and is a regulator of wingless signalingEfficient herpes simplex virus 1 replication requires cellular ATR pathway proteinsThe relationship between mTOR signalling pathway and recombinant antibody productivity in CHO cell lines.The leukemia-associated Rho guanine nucleotide exchange factor LARG is required for efficient replication stress signaling.Quantitative proteomic identification of the BRCA1 ubiquitination substrates.Reptin regulates DNA double strand breaks repair in human hepatocellular carcinoma.Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteomeATM protein physically and functionally interacts with proliferating cell nuclear antigen to regulate DNA synthesis.mTOR complex 2 signaling and functionsGenetic evidence links the ASTRA protein chaperone component Tti2 to the SAGA transcription factor Tra1.
P2860
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P2860
Tel2 regulates the stability of PI3K-related protein kinases
description
2007 nî lūn-bûn
@nan
2007 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
Tel2 regulates the stability of PI3K-related protein kinases
@ast
Tel2 regulates the stability of PI3K-related protein kinases
@en
Tel2 regulates the stability of PI3K-related protein kinases
@en-gb
Tel2 regulates the stability of PI3K-related protein kinases
@nl
type
label
Tel2 regulates the stability of PI3K-related protein kinases
@ast
Tel2 regulates the stability of PI3K-related protein kinases
@en
Tel2 regulates the stability of PI3K-related protein kinases
@en-gb
Tel2 regulates the stability of PI3K-related protein kinases
@nl
prefLabel
Tel2 regulates the stability of PI3K-related protein kinases
@ast
Tel2 regulates the stability of PI3K-related protein kinases
@en
Tel2 regulates the stability of PI3K-related protein kinases
@en-gb
Tel2 regulates the stability of PI3K-related protein kinases
@nl
P2093
P3181
P1433
P1476
Tel2 regulates the stability of PI3K-related protein kinases
@en
P2093
Haijuan Yang
Hiroyuki Takai
Kaori K Takai
Richard C Wang
P304
P3181
P356
10.1016/J.CELL.2007.10.052
P407
P577
2007-12-28T00:00:00Z