Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses. - Wikidata - awgldk - TriplyDB

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.

Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.

http://www.wikidata.org/entity/Q24634270

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What can we learn about autism from studying fragile X syndrome?Behavioral phenotypes of genetic mouse models of autism.Behavioral and Neuroanatomical Phenotypes in Mouse Models of Autism Fragile X-like behaviors and abnormal cortical dendritic spines in cytoplasmic FMR1-interacting protein 2-mutant mice.Complete or partial reduction of the Met receptor tyrosine kinase in distinct circuits differentially impacts mouse behavior Haploinsufficiency of Cyfip1 produces fragile X-like phenotypes in mice Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and Back Functional magnetic resonance imaging in awake transgenic fragile X rats: evidence of dysregulation in reward processing in the mesolimbic/habenular neural circuit Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.Genetic manipulation of STEP reverses behavioral abnormalities in a fragile X syndrome mouse model.Acetaminophen differentially enhances social behavior and cortical cannabinoid levels in inbred mice Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.Rescue of fragile X syndrome phenotypes in Fmr1 KO mice by the small-molecule PAK inhibitor FRAX486.Onset and progression of behavioral and molecular phenotypes in a novel congenic R6/2 line exhibiting intergenerational CAG repeat stability.Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction Chrna7 deficient mice manifest no consistent neuropsychiatric and behavioral phenotypes.The GABAA receptor is an FMRP target with therapeutic potential in fragile X syndrome.Normal Performance of Fmr1 Mice on a Touchscreen Delayed Nonmatching to Position Working Memory Task Behavioral changes following a single episode of early-life seizures support the latent development of an autistic phenotype.Stem cells and modeling of autism spectrum disorders.Behavioral analysis of male and female Fmr1 knockout mice on C57BL/6 background.In vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndrome The role of glucocorticoid receptor-dependent activity in the amygdala central nucleus and reversibility of early-life stress programmed behavior.Autism-related neuroligin-3 mutation alters social behavior and spatial learning.Repetitive behavior profile and supersensitivity to amphetamine in the C58/J mouse model of autism.Modeling fragile X syndrome in the Fmr1 knockout mouse Absence of strong strain effects in behavioral analyses of Shank3-deficient mice mGluR5 ablation in cortical glutamatergic neurons increases novelty-induced locomotion The autism diagnosis in translation: shared affect in children and mouse models of ASD.Genetic reduction of muscarinic M4 receptor modulates analgesic response and acoustic startle response in a mouse model of fragile X syndrome (FXS).Comprehensive neurocognitive endophenotyping strategies for mouse models of genetic disorders The modulation of fragile X behaviors by the muscarinic M4 antagonist, tropicamide Genetic background modulates behavioral impairments in R6/2 mice and suggests a role for dominant genetic modifiers in Huntington’s disease pathogenesis.Maternal genetic mutations as gestational and early life influences in producing psychiatric disease-like phenotypes in mice.Hyperactivity, perseveration and increased responding during attentional rule acquisition in the Fragile X mouse model Genetic background modulates phenotypes of serotonin transporter Ala56 knock-in mice Protein-restricted diet during pregnancy after insemination alters behavioral phenotypes of the progeny Effects of a social stimulus on gene expression in a mouse model of fragile X syndrome Rai1 Haploinsufficiency Is Associated with Social Abnormalities in Mice.

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Modifying behavioral phenotypes in Fmr1KO mice: genetic background differences reveal autistic-like responses.

http://www.wikidata.org/entity/Q24634270

description

2011 nî lūn-bûn

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2011 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2011 թվականի հունվարին հրատարակված գիտական հոդված

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2011年の論文

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name

Modifying behavioral phenotype ...... reveal autistic-like responses

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Modifying behavioral phenotype ...... eveal autistic-like responses.

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Modifying behavioral phenotype ...... eveal autistic-like responses.

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type

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Modifying behavioral phenotype ...... reveal autistic-like responses

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Modifying behavioral phenotype ...... eveal autistic-like responses.

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Modifying behavioral phenotype ...... eveal autistic-like responses.

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Modifying behavioral phenotype ...... reveal autistic-like responses

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Modifying behavioral phenotype ...... eveal autistic-like responses.

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Modifying behavioral phenotype ...... eveal autistic-like responses.

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Autism Research

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Modifying behavioral phenotype ...... eveal autistic-like responses.

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Alexia M Thomas

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Corinne M Spencer

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Ekaterina Serysheva

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Lisa A Yuva-Paylor

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Olga Alekseyenko

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Richard Paylor

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Shannon M Hamilton

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P2860

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

FMR1 protein: conserved RNP family domains and selective RNA binding

Abnormal behavior in a chromosome-engineered mouse model for human 15q11-13 duplication seen in autism

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism

Mouse behavioral tasks relevant to autism: phenotypes of 10 inbred strains

Wild-type male offspring of fmr-1+/- mothers exhibit characteristics of the fragile X phenotype

Ultrasonic vocalizations: a tool for behavioural phenotyping of mouse models of neurodevelopmental disorders.

A mouse model of the human Fragile X syndrome I304N mutation.

Development of a mouse test for repetitive, restricted behaviors: relevance to autism.

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40-56

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10.1002/AUR.168

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21268289

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