Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids
about
Interventions for itch in people with advanced chronic kidney diseaseWhy we scratch an itch: the molecules, cells and circuits of itchOpioid receptors: toward separation of analgesic from undesirable effectsNew insights into the mechanisms of itch: are pain and itch controlled by distinct mechanisms?The cell biology of acute itchInsights into bombesin receptors and ligands: Highlighting recent advancesNeuroimmune interactions in itch: Do chronic itch, chronic pain, and chronic cough share similar mechanisms?Facilitation of TRPV4 by TRPV1 is required for itch transmission in some sensory neuron populationsGRPR/PI3Kγ: Partners in Central Transmission of ItchNeural processing of itch.Chronic itch development in sensory neurons requires BRAF signaling pathways.Distinct functions of opioid-related peptides and gastrin-releasing peptide in regulating itch and pain in the spinal cord of primates.Itch mechanisms and circuits.Cross-inhibition of NMBR and GRPR signaling maintains normal histaminergic itch transmissionDifferential expressions of the alternatively spliced variant mRNAs of the µ opioid receptor gene, OPRM1, in brain regions of four inbred mouse strainsRevolution in GPCR signalling: opioid receptor heteromers as novel therapeutic targets: IUPHAR review 10.Descending control of itch transmission by the serotonergic system via 5-HT1A-facilitated GRP-GRPR signalingRole of spinal bombesin-responsive neurons in nonhistaminergic itch.Physiological function of gastrin-releasing peptide and neuromedin B receptors in regulating itch scratching behavior in the spinal cord of miceIn vivo opioid receptor heteromerization: where do we stand?Neuraxial opioid-induced itch and its pharmacological antagonismGastrin-releasing peptide receptor (GRPR) mediates chemotaxis in neutrophilsMu Opioid Splice Variant MOR-1K Contributes to the Development of Opioid-Induced Hyperalgesia.Functional homomers and heteromers of dopamine D2L and D3 receptors co-exist at the cell surfaceOxidative stress induces itch via activation of transient receptor potential subtype ankyrin 1 in mice.Molecular and cellular mechanisms that initiate pain and itch.Salvinorin A analogues PR-37 and PR-38 attenuate compound 48/80-induced itch responses in miceSplice variation of the mu-opioid receptor and its effect on the action of opioids.Hydrogen sulfide-induced itch requires activation of Cav3.2 T-type calcium channel in mice.Gastrin-releasing peptide receptors in the central nervous system: role in brain function and as a drug target.Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.Roles for substance P and gastrin-releasing peptide as neurotransmitters released by primary afferent pruriceptors.The TGR5 receptor mediates bile acid-induced itch and analgesiaClinical Efficacy and Safety of Naltrexone Combination Therapy in Older Patients with Severe PruritusItch and analgesia resulting from intrathecal application of morphine: contrasting effects on different populations of trigeminothalamic tract neurons.The prevalence, maintenance, and relevance of G protein-coupled receptor oligomerizationExcitatory superficial dorsal horn interneurons are functionally heterogeneous and required for the full behavioral expression of pain and itch.On the g-protein-coupled receptor heteromers and their allosteric receptor-receptor interactions in the central nervous system: focus on their role in pain modulationDifferential expression and HIV-1 regulation of μ-opioid receptor splice variants across human central nervous system cell types.The ion channel TRPA1 is required for chronic itch.
P2860
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P2860
Unidirectional cross-activation of GRPR by MOR1D uncouples itch and analgesia induced by opioids
description
2011 nî lūn-bûn
@nan
2011 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Unidirectional cross-activatio ...... d analgesia induced by opioids
@ast
Unidirectional cross-activatio ...... d analgesia induced by opioids
@en
Unidirectional cross-activatio ...... d analgesia induced by opioids
@nl
type
label
Unidirectional cross-activatio ...... d analgesia induced by opioids
@ast
Unidirectional cross-activatio ...... d analgesia induced by opioids
@en
Unidirectional cross-activatio ...... d analgesia induced by opioids
@nl
prefLabel
Unidirectional cross-activatio ...... d analgesia induced by opioids
@ast
Unidirectional cross-activatio ...... d analgesia induced by opioids
@en
Unidirectional cross-activatio ...... d analgesia induced by opioids
@nl
P2093
P2860
P921
P3181
P1433
P1476
Unidirectional cross-activatio ...... d analgesia induced by opioids
@en
P2093
Feng-Fang Tsai
Horace H Loh
Ji-Young Kim
Joseph Jeffry
Michael Ross
Qi-Fang Li
Seungil Kim
Yan-Gang Sun
Zhong-Chun Liu
Zhou-Feng Chen
P2860
P304
P3181
P356
10.1016/J.CELL.2011.08.043
P407
P50
P577
2011-10-14T00:00:00Z