The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms
about
Gene expression profiling of monkeypox virus-infected cells reveals novel interfaces for host-virus interactionsOrthopoxvirus genes that mediate disease virulence and host tropismThe herpes simplex virus type 1 U(S)11 protein interacts with protein kinase R in infected cells and requires a 30-amino-acid sequence adjacent to a kinase substrate domainThe molecular basis of viral oncolysis: usurpation of the Ras signaling pathway by reovirusInhibition of PACT-mediated activation of PKR by the herpes simplex virus type 1 Us11 protein.A herpesvirus genetic element which affects translation in the absence of the viral GADD34 functionImpact of protein kinase PKR in cell biology: from antiviral to antiproliferative actionPhosphorylation of HIV Tat by PKR increases interaction with TAR RNA and enhances transcriptionOncogenes: The Passport for Viral Oncolysis Through PKR InhibitionHost-range restriction of vaccinia virus E3L deletion mutant can be overcome in vitro, but not in vivo, by expression of the influenza virus NS1 proteinDevelopment of eczema vaccinatum in atopic mouse models and efficacy of MVA vaccination against lethal poxviral infectionPoxviruses deploy genomic accordions to adapt rapidly against host antiviral defensesReplication of modified vaccinia virus Ankara in primary chicken embryo fibroblasts requires expression of the interferon resistance gene E3L.Evasion of cellular antiviral responses by human cytomegalovirus TRS1 and IRS1A herpesvirus ribosome-associated, RNA-binding protein confers a growth advantage upon mutants deficient in a GADD34-related function.Double-stranded RNA-activated protein kinase mediates virus-induced apoptosis: a new role for an old actor.Inhibition of double-stranded RNA-dependent protein kinase PKR by vaccinia virus E3: role of complex formation and the E3 N-terminal domain.The second-site mutation in the herpes simplex virus recombinants lacking the gamma134.5 genes precludes shutoff of protein synthesis by blocking the phosphorylation of eIF-2alphaThe herpes simplex virus US11 protein effectively compensates for the gamma1(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2.Alpha/beta interferons potentiate virus-induced apoptosis through activation of the FADD/Caspase-8 death signaling pathwayBoth carboxy- and amino-terminal domains of the vaccinia virus interferon resistance gene, E3L, are required for pathogenesis in a mouse model.Characterization of a ranavirus inhibitor of the antiviral protein kinase PKRDouble-stranded RNA-activated protein kinase (PKR) is negatively regulated by 60S ribosomal subunit protein L18Translational control of viral gene expression in eukaryotesMolecular mechanisms of viral inhibitors of RIG-I-like receptors.Second-site mutation outside of the U(S)10-12 domain of Deltagamma(1)34.5 herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase R and partially restores neurovirulence.Development of resistance to RNAi in mammalian cellsEbola virus VP35 protein binds double-stranded RNA and inhibits alpha/beta interferon production induced by RIG-I signaling.Regulation of herpes simplex virus gamma(1)34.5 expression and oncolysis of diffuse liver metastases by Myb34.5.Myxoma virus protein M029 is a dual function immunomodulator that inhibits PKR and also conscripts RHA/DHX9 to promote expanded host tropism and viral replicationPoxvirus immunomodulatory strategies: current perspectivesVirus infection rapidly activates the P58(IPK) pathway, delaying peak kinase activation to enhance viral replication.TAR RNA-binding protein is an inhibitor of the interferon-induced protein kinase PKRThe Ebola virus VP35 protein functions as a type I IFN antagonist.Reversal of the interferon-sensitive phenotype of a vaccinia virus lacking E3L by expression of the reovirus S4 gene.Delay of vaccinia virus-induced apoptosis in nonpermissive Chinese hamster ovary cells by the cowpox virus CHOhr and adenovirus E1B 19K genes.Rescue of vaccinia virus lacking the E3L gene by mutants of E3L.Double-stranded RNA is a trigger for apoptosis in vaccinia virus-infected cells.Direct comparison of antigen production and induction of apoptosis by canarypox virus- and modified vaccinia virus ankara-human immunodeficiency virus vaccine vectorsThe gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1alpha to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-
P2860
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P2860
The E3L and K3L vaccinia virus gene products stimulate translation through inhibition of the double-stranded RNA-dependent protein kinase by different mechanisms
description
1993 nî lūn-bûn
@nan
1993 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի մարտին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@ast
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@en
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@nl
type
label
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@ast
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@en
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@nl
prefLabel
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@ast
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@en
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@nl
P2093
P2860
P3181
P1433
P1476
The E3L and K3L vaccinia virus ...... kinase by different mechanisms
@en
P2093
B L Jacobs
M V Davies
R J Kaufman
P2860
P304
P3181
P407
P577
1993-03-01T00:00:00Z