IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancer - Wikidata - awgldk - TriplyDB

IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancer

IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancer

http://www.wikidata.org/entity/Q24642963

about

The IKK complex contributes to the induction of autophagy A novel role of IKKalpha in the mediation of UVB-induced G0/G1 cell cycle arrest response by suppressing Cyclin D1 expression Small-molecule inhibitors of IκB kinase (IKK) and IKK-related kinases Deciphering the role of nuclear and cytoplasmic IKKα in skin cancer Developmental factor IRF6 exhibits tumor suppressor activity in squamous cell carcinomas.TP63 and TP73 in cancer, an unresolved "family" puzzle of complexity, redundancy and hierarchy.Exome Sequencing of Oral Squamous Cell Carcinoma Reveals Molecular Subgroups and Novel Therapeutic Opportunities The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.Conditional ablation of Ikkb inhibits melanoma tumor development in mice.Deep-sequencing analysis of the mouse transcriptome response to infection with Brucella melitensis strains of differing virulence.Klf4 overexpression activates epithelial cytokines and inflammation-mediated esophageal squamous cell cancer in mice.Elevated IKKα accelerates the differentiation of human neuronal progenitor cells and induces MeCP2-dependent BDNF expression.ZNF750 is expressed in differentiated keratinocytes and regulates epidermal late differentiation genes Induction of ΔNp63 by the newly identified keratinocyte-specific transforming growth factor β Signaling Pathway with Smad2 and IκB Kinase α in squamous cell carcinoma.Targeted deletion and lipidomic analysis identify epithelial cell COX-2 as a major driver of chemically induced skin cancer The IκB kinase complex in NF-κB regulation and beyond.NF-kappaB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis.Inhibitor of apoptosis-stimulating protein of p53 (iASPP) prevents senescence and is required for epithelial stratification.IKKα is involved in kidney recovery and regeneration of acute ischemia/reperfusion injury in mice through IL10-producing regulatory T cells.IKKα contributes to UVB-induced VEGF expression by regulating AP-1 transactivation.Interferon Regulatory Factor 6 Has a Protective Role in the Host Response to Endotoxic Shock Comparative transcriptomic profiling of hydrogen peroxide signaling networks in zebrafish and human keratinocytes: Implications toward conservation, migration and wound healing Differentiation therapy for hepatocellular carcinoma: Multifaceted effects of miR-148a on tumor growth and phenotype and liver fibrosis.Mouse Genetic Models Reveal Surprising Functions of IkB Kinase Alpha in Skin Development and Skin Carcinogenesis.Deregulation of IKBKE is associated with tumor progression, poor prognosis, and cisplatin resistance in ovarian cancer IKKα regulates human keratinocyte migration through surveillance of the redox environment.Inhibitory kappa B Kinases as targets for pharmacological regulation.Stem cells behind the barrier.The role of barrier genes in epidermal malignancy.SMAD4 is essential for generating subtypes of neurons during cerebellar development.Genome-wide association study identifies three novel susceptibility loci for severe Acne vulgaris.Complementary expression and repulsive signaling suggest that EphB2 and ephrin-B1 are possibly involved in epithelial boundary formation at the squamocolumnar junction in the rodent stomach.NF-κB Members Left Home: NF-κB-Independent Roles in Cancer.GATA3 inhibits proliferation and induces expression of both early and late differentiation markers in keratinocytes of the human epidermis.

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IKKalpha, a critical regulator of epidermal differentiation and a suppressor of skin cancer

http://www.wikidata.org/entity/Q24642963

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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type

label

IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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prefLabel

IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

@ast

IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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The EMBO Journal

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IKKalpha, a critical regulator ...... nd a suppressor of skin cancer

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Alok K Sil

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Pascal Descargues

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Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported

P2860

IKK-gamma is an essential regulatory subunit of the IkappaB kinase complex

Mad: a heterodimeric partner for Max that antagonizes Myc transcriptional activity

IKK-1 and IKK-2: cytokine-activated IkappaB kinases essential for NF-kappaB activation

A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

IkappaB kinase-beta: NF-kappaB activation and complex formation with IkappaB kinase-alpha and NIK

Mutations in IRF6 cause Van der Woude and popliteal pterygium syndromes

IKK1-deficient mice exhibit abnormal development of skin and skeleton

Abnormal skin, limb and craniofacial morphogenesis in mice deficient for interferon regulatory factor 6 (Irf6)

A critical role for I kappaB kinase alpha in the development of human and mouse squamous cell carcinomas

Mechanisms of TGF-beta signaling from cell membrane to the nucleus

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2639-47

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4894599

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10.1038/EMBOJ.2008.196

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20

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27

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2008-10-22T00:00:00Z

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23282324

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18818691

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regulation of gene expression

integumentary system

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2556095

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