Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments
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Loss of Niemann Pick type C proteins 1 and 2 greatly enhances HIV infectivity and is associated with accumulation of HIV Gag and cholesterol in late endosomes/lysosomesEbola virus entry requires the cholesterol transporter Niemann-Pick C1Proteome-wide dysregulation by PRA1 depletion delineates a role of PRA1 in lipid transport and cell migrationGenetic dissection of a cell-autonomous neurodegenerative disorder: lessons learned from mouse models of Niemann-Pick disease type CGenomic expression analyses reveal lysosomal, innate immunity proteins, as disease correlates in murine models of a lysosomal storage disorderInfection of female primary lower genital tract epithelial cells after natural pseudotyping of HIV-1: possible implications for sexual transmission of HIV-1.Live cell visualization of the interactions between HIV-1 Gag and the cellular RNA-binding protein Staufen1Niemann-Pick C1 functions independently of Niemann-Pick C2 in the initial stage of retrograde transport of membrane-impermeable lysosomal cargo.HIV-1 enhances mTORC1 activity and repositions lysosomes to the periphery by co-opting Rag GTPases.The antiviral effector IFITM3 disrupts intracellular cholesterol homeostasis to block viral entry.Cholesterol depletion inactivates XMRV and leads to viral envelope protein release from virions: evidence for role of cholesterol in XMRV infectionCathepsin B & L are not required for ebola virus replicationHIV-1 suppressive sequences are modulated by Rev transport of unspliced RNA and are required for efficient HIV-1 production.Cholesterol dependence of collagen and echovirus 1 trafficking along the novel α2β1 integrin internalization pathway.Cholesterol-rich lipid rafts are required for release of infectious human respiratory syncytial virus particles.Neuronal and epithelial cell rescue resolves chronic systemic inflammation in the lipid storage disorder Niemann-Pick C.HIV Assembly and Budding: Ca(2+) Signaling and Non-ESCRT Proteins Set the Stage.New insights into HIV assembly and trafficking.Characterization of staufen1 ribonucleoproteins by mass spectrometry and biochemical analyses reveal the presence of diverse host proteins associated with human immunodeficiency virus type 1.Potential vaccines and post-exposure treatments for filovirus infections.Subversion of NPC1 pathway of cholesterol transport by Anaplasma phagocytophilum.Disruption of multivesicular body vesicles does not affect major histocompatibility complex (MHC) class II-peptide complex formation and antigen presentation by dendritic cellsSequestration of cholesterol within the host late endocytic pathway restricts liver-stage Plasmodium development.Niemann-Pick type C disease: molecular mechanisms and potential therapeutic approaches.Roles for biological membranes in regulating human immunodeficiency virus replication and progress in the development of HIV therapeutics that target lipid metabolism.Imipramine Inhibits Chikungunya Virus Replication in Human Skin Fibroblasts through Interference with Intracellular Cholesterol Trafficking.Clathrin mediates infectious hepatitis C virus particle egress.Antiviral activity of cationic amphiphilic drugs.Exacerbating and reversing lysosomal storage diseases: from yeast to humans.Rab3a-Bound CD63 Is Degraded and Rab3a-Free CD63 Is Incorporated into HIV-1 Particles.Therapy of Pelizaeus-Merzbacher disease in mice by feeding a cholesterol-enriched diet
P2860
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P2860
Deficiency of niemann-pick type C-1 protein impairs release of human immunodeficiency virus type 1 and results in Gag accumulation in late endosomal/lysosomal compartments
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@ast
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@en
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@nl
type
label
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@ast
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@en
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@nl
prefLabel
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@ast
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@en
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@nl
P2093
P2860
P356
P1433
P1476
Deficiency of niemann-pick typ ...... dosomal/lysosomal compartments
@en
P2093
Ebony M Coleman
Ihid Carneiro Leao
James E K Hildreth
Robin Shepard Broughton
Yuyang Tang
P2860
P304
P356
10.1128/JVI.00259-09
P407
P577
2009-08-01T00:00:00Z