Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure - Wikidata - awgldk - TriplyDB

Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure

Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure

http://www.wikidata.org/entity/Q24646933

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Myostatin from the heart: local and systemic actions in cardiac failure and muscle wasting Cardiac cachexia: hic et nunc Skeletal muscle wasting in cachexia and sarcopenia: molecular pathophysiology and impact of exercise training Exercise intolerance in heart failure with preserved ejection fraction: more than a heart problem Overexpression of Latent TGFβ Binding Protein 4 in Muscle Ameliorates Muscular Dystrophy through Myostatin and TGFβ Sarcopenia in heart failure: mechanisms and therapeutic strategies Molecular pathways leading to loss of skeletal muscle mass in cancer cachexia--can findings from animal models be translated to humans?Telethonin deficiency is associated with maladaptation to biomechanical stress in the mammalian heart Cardiac myocyte follistatin-like 1 functions to attenuate hypertrophy following pressure overload GDF11 does not rescue aging-related pathological hypertrophy The Role of Exercise in Cardiac Aging: From Physiology to Molecular Mechanisms Enhanced skeletal muscle expression of extracellular superoxide dismutase mitigates streptozotocin-induced diabetic cardiomyopathy by reducing oxidative stress and aberrant cell signaling.Myostatin mediates abdominal aortic atherosclerosis progression by inducing vascular smooth muscle cell dysfunction and monocyte recruitment.PGC-1α promotes nitric oxide antioxidant defenses and inhibits FOXO signaling against cardiac cachexia in mice.SMAD3 augments FoxO3-induced MuRF-1 promoter activity in a DNA-binding-dependent manner.Myostatin is elevated in congenital heart disease and after mechanical unloading Aerobic exercise training prevents heart failure-induced skeletal muscle atrophy by anti-catabolic, but not anabolic actions.Biochemistry and Biology of GDF11 and Myostatin: Similarities, Differences, and Questions for Future Investigation Is Growth Differentiation Factor 11 a Realistic Therapeutic for Aging-Dependent Muscle Defects?Silencing Myostatin Using Cholesterol-conjugated siRNAs Induces Muscle Growth Supraphysiological levels of GDF11 induce striated muscle atrophy Cardiac myocyte-specific ablation of follistatin-like 3 attenuates stress-induced myocardial hypertrophy.Heart over mind: metabolic control of white adipose tissue and liver Myostatin and IGF-I signaling in end-stage human heart failure: a qRT-PCR study.Taking pressure off the heart: the ins and outs of atrophic remodelling.Highly specific detection of myostatin prodomain by an immunoradiometric sandwich assay in serum of healthy individuals and patients.Synergistic and antagonistic interplay between myostatin gene expression and physical activity levels on gene expression patterns in triceps Brachii muscles of C57/BL6 mice.Treating cancer cachexia to treat cancer The role of myostatin in muscle wasting: an overview Targeting the myostatin signaling pathway to treat muscle wasting diseases Higher Plasma Myostatin Levels in Cor Pulmonale Secondary to Chronic Obstructive Pulmonary Disease.Sarcopenia and cachexia: the adaptations of negative regulators of skeletal muscle mass.Molecular and cellular mechanisms of skeletal muscle atrophy: an update.Finding good biomarkers for sarcopenia.Research on cachexia, sarcopenia and skeletal muscle in cardiology.Circulating Growth Differentiation Factor 11/8 Levels Decline With Age.Sarcopenic obesity and the pathogenesis of exercise intolerance in heart failure with preserved ejection fraction.Paracrine and endocrine modes of myostatin action.Cardiac-Secreted Factors as Peripheral Metabolic Regulators and Potential Disease Biomarkers.Molecular mechanisms and signaling pathways of angiotensin II-induced muscle wasting: potential therapeutic targets for cardiac cachexia

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Genetic deletion of myostatin from the heart prevents skeletal muscle atrophy in heart failure

http://www.wikidata.org/entity/Q24646933

description

2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年論文

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2010年论文

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name

Genetic deletion of myostatin ...... uscle atrophy in heart failure

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Genetic deletion of myostatin ...... uscle atrophy in heart failure

@en

Genetic deletion of myostatin ...... uscle atrophy in heart failure

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type

label

Genetic deletion of myostatin ...... uscle atrophy in heart failure

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Genetic deletion of myostatin ...... uscle atrophy in heart failure

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Genetic deletion of myostatin ...... uscle atrophy in heart failure

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prefLabel

Genetic deletion of myostatin ...... uscle atrophy in heart failure

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Genetic deletion of myostatin ...... uscle atrophy in heart failure

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Genetic deletion of myostatin ...... uscle atrophy in heart failure

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CIRCULATIONAHA.109.882068

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Genetic deletion of myostatin ...... uscle atrophy in heart failure

@en

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Allen York

http://www.w3.org/2001/XMLSchema#string

Jian Xu

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Joerg Heineke

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Mannix Auger-Messier

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Michelle Sargent

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Stephen Welle

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P2860

Heart Disease and Stroke Statistics--2008 Update: A Report From the American Heart Association Statistics Committee and Stroke Statistics Subcommittee

Myostatin regulates cardiomyocyte growth through modulation of Akt signaling

Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member

Myostatin, a transforming growth factor-beta superfamily member, is expressed in heart muscle and is upregulated in cardiomyocytes after infarct.

Induction of cachexia in mice by systemically administered myostatin.

Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy.

Prognostic importance of weight loss in chronic heart failure and the effect of treatment with angiotensin-converting-enzyme inhibitors: an observational study.

Wasting as independent risk factor for mortality in chronic heart failure.

Insulin-like growth factor-1 mediates stretch-induced upregulation of myostatin expression in neonatal rat cardiomyocytes.

Age-dependent effect of myostatin blockade on disease severity in a murine model of limb-girdle muscular dystrophy.

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3

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Jeffery D. Molkentin

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40907753

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20065166

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