Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor - Wikidata - awgldk - TriplyDB

Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

http://www.wikidata.org/entity/Q24648004

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Enzymatic and structural insights for substrate specificity of a family of jumonji histone lysine demethylases The AAA-ATPase VCP/p97 promotes 53BP1 recruitment by removing L3MBTL1 from DNA double-strand breaks Distinct mode of methylated lysine-4 of histone H3 recognition by tandem tudor-like domains of Spindlin1 Phf19 links methylated Lys36 of histone H3 to regulation of Polycomb activity Molecular basis for H3K36me3 recognition by the Tudor domain of PHF1 RNF8- and RNF168-dependent degradation of KDM4A/JMJD2A triggers 53BP1 recruitment to DNA damage sites Sgf29 binds histone H3K4me2/3 and is required for SAGA complex recruitment and histone H3 acetylation.Methylation-state-specific recognition of histones by the MBT repeat protein L3MBTL2 PHD finger recognition of unmodified histone H3R2 links UHRF1 to regulation of euchromatic gene expression Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes PHF20 is an effector protein of p53 double lysine methylation that stabilizes and activates p53 Structural and functional coordination of DNA and histone methylation The role of histone demethylases in cancer therapy KDM4/JMJD2 histone demethylases: epigenetic regulators in cancer cells Protein lysine acetylation by p300/CBP Histone demethylase KDM4B regulates otic vesicle invagination via epigenetic control of Dlx3 expression.Structural Basis for the Recognition of Methylated Histone H3K36 by the Eaf3 Subunit of Histone Deacetylase Complex Rpd3S Structure of an atypical Tudor domain in theDrosophilaPolycomblike protein Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family Solution Structure and Molecular Interactions of Lamin B Receptor Tudor Domain Solution structure of the Pdp1 PWWP domain reveals its unique binding sites for methylated H4K20 and DNA Inhibition of osteogenic differentiation of human adipose-derived stromal cells by retinoblastoma binding protein 2 repression of RUNX2-activated transcription Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease Direct inhibition of Gcn5 protein catalytic activity by polyglutamine-expanded ataxin-7.Modulation of epigenetic targets for anticancer therapy: clinicopathological relevance, structural data and drug discovery perspectives A complex small RNA repertoire is generated by a plant/fungal-like machinery and effected by a metazoan-like Argonaute in the single-cell human parasite Toxoplasma gondii.A combinatorial H4 tail library for exploring the histone code.A homogeneous method for investigation of methylation-dependent protein-protein interactions in epigenetics A method for systematic mapping of protein lysine methylation identifies functions for HP1β in DNA damage response.Expanding the landscape of chromatin modification (CM)-related functional domains and genes in human.Coordinated chromatin control: structural and functional linkage of DNA and histone methylation.Preparation of recombinant peptides with site- and degree-specific lysine (13)C-methylation.JMJD2A contributes to breast cancer progression through transcriptional repression of the tumor suppressor ARHI Molecular recognition of H3/H4 histone tails by the tudor domains of JMJD2A: a comparative molecular dynamics simulations study A new isoform of the histone demethylase JMJD2A/KDM4A is required for skeletal muscle differentiation.Computational methods for de novo protein design and its applications to the human immunodeficiency virus 1, purine nucleoside phosphorylase, ubiquitin specific protease 7, and histone demethylases.Application of Celluspots peptide arrays for the analysis of the binding specificity of epigenetic reading domains to modified histone tails.Utility-aware screening with clique-oriented prioritization.Nuclear role of WASp in the pathogenesis of dysregulated TH1 immunity in human Wiskott-Aldrich syndrome.The PHD finger: a versatile epigenome reader.

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Distinct binding modes specify the recognition of methylated histones H3K4 and H4K20 by JMJD2A-tudor

http://www.wikidata.org/entity/Q24648004

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2008 nî lūn-bûn

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2008 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2008 թվականի հունվարին հրատարակված գիտական հոդված

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2008年の論文

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2008年学术文章

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2008年学术文章

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2008年学术文章

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2008年學術文章

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Nature Structural & Molecular Biology

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Distinct binding modes specify ...... H3K4 and H4K20 by JMJD2A-tudor

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Georges Mer

http://www.w3.org/2001/XMLSchema#string

James R Thompson

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Joseph Lee

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Maria Victoria Botuyan

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P2860

Tudor, MBT and chromo domains gauge the degree of lysine methylation

Structural basis of the recognition of a methylated histone tail by JMJD2A

Reversal of histone lysine trimethylation by the JMJD2 family of histone demethylases

Structural basis for the methylation state-specific recognition of histone H4-K20 by 53BP1 and Crb2 in DNA repair

SMN tudor domain structure and its interaction with the Sm proteins

Structure of HP1 chromodomain bound to a lysine 9-methylated histone H3 tail

Structure of the HP1 chromodomain bound to histone H3 methylated at lysine 9

Crystal structures of histone demethylase JMJD2A reveal basis for substrate specificity

Specificity and mechanism of JMJD2A, a trimethyllysine-specific histone demethylase

Chromatin modifications and their function

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109-11

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10.1038/NSMB1326

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1

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15

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5765028

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1013066032

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18084306

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structural biology

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2211384

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