Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells - Wikidata - awgldk - TriplyDB

Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells

Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells

http://www.wikidata.org/entity/Q24648786

about

Escherichia coli Subtilase Cytotoxin Dinosaurs and ancient civilizations: reflections on the treatment of cancer Protein Folding and Mechanisms of Proteostasis Endoplasmic reticulum chaperones and oxidoreductases: critical regulators of tumor cell survival and immunorecognition The unfolded protein response regulator GRP78 is a novel predictive biomarker in colorectal cancer.Tumor cell survival pathways activated by photodynamic therapy: a molecular basis for pharmacological inhibition strategies The endoplasmic reticulum protein folding factory and its chaperones: new targets for drug discovery?Fortilin binds IRE1α and prevents ER stress from signaling apoptotic cell death.Structure, biological functions and applications of the AB5 toxins.Endoplasmic reticulum stress and cancer.Targeting the unfolded protein response in glioblastoma cells with the fusion protein EGF-SubA.Inhibition of established micrometastases by targeted drug delivery via cell surface-associated GRP78.The interconnectedness of cancer cell signaling.Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signaling Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy Design, purification and assessment of GRP78 binding peptide-linked Subunit A of Subtilase cytotoxic for targeting cancer cells.Elevated GRP78 expression is associated with poor prognosis in patients with pancreatic cancer Low dose of GRP78-targeting subtilase cytotoxin improves the efficacy of photodynamic therapy in vivo.GRP78-targeting subtilase cytotoxin sensitizes cancer cells to photodynamic therapy.The critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapies Endoplasmic reticulum stress: its role in disease and novel prospects for therapy.The War on Cancer rages on.Prostate cancer and the unfolded protein response.Endoplasmic reticulum stress response in cancer: molecular mechanism and therapeutic potential.Unfolded protein response in cancer: the physician's perspective Molecular chaperones as therapeutic targets to counteract proteostasis defects.Targeted toxins in brain tumor therapy.Endoplasmic reticulum and the unfolded protein response: dynamics and metabolic integration Targeting the unfolded protein response in disease.Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential Structure aided design of a Neu5Gc specific lectin.Sec62 protein level is crucial for the ER stress tolerance of prostate cancer.Targeting GRP78 to enhance melanoma cell death.The presence of extracellular matrix alters the chondrocyte response to endoplasmic reticulum stress.Inducing apoptosis in chemotherapy-resistant B-lineage acute lymphoblastic leukaemia cells by targeting HSPA5, a master regulator of the anti-apoptotic unfolded protein response signalling network.Exploring Cytotoxic mRNAs as a Novel Class of Anti-cancer Biotherapeutics.Anti-Cancer Natural Products and Their Bioactive Compounds Inducing ER Stress-Mediated Apoptosis: A Review

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P2860

Chaperone-targeting cytotoxin and endoplasmic reticulum stress-inducing drug synergize to kill cancer cells

http://www.wikidata.org/entity/Q24648786

description

2009 nî lūn-bûn

@nan

2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի նոյեմբերին հրատարակված գիտական հոդված

@hy

2009年の論文

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2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@ast

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@en

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@nl

type

label

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@ast

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@en

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@nl

prefLabel

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@ast

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@en

Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@nl

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Chaperone-targeting cytotoxin ...... synergize to kill cancer cells

@en

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Arcadius V Krivoshein

http://www.w3.org/2001/XMLSchema#string

Carl V Hamby

http://www.w3.org/2001/XMLSchema#string

Harrison Brand

http://www.w3.org/2001/XMLSchema#string

James C Paton

http://www.w3.org/2001/XMLSchema#string

John Pizzonia

http://www.w3.org/2001/XMLSchema#string

Joseph M Backer

http://www.w3.org/2001/XMLSchema#string

Kenneth S Gilbert

http://www.w3.org/2001/XMLSchema#string

Marina V Backer

http://www.w3.org/2001/XMLSchema#string

Yonaton S Ray

http://www.w3.org/2001/XMLSchema#string

P2860

Caspases: the executioners of apoptosis

Endoplasmic reticulum stress: cell life and death decisions.

Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors

A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli.

Subtilase cytotoxin activates PERK, IRE1 and ATF6 endoplasmic reticulum stress-signalling pathways.

In vitro and in vivo studies of a VEGF121/rGelonin chimeric fusion toxin targeting the neovasculature of solid tumors.

DAB389EGF fusion protein therapy of refractory glioblastoma multiforme.

GRP78/BiP is required for cell proliferation and protecting the inner cell mass from apoptosis during early mouse embryonic development.

Inhibition of anthrax protective antigen outside and inside the cell.

The SERCA pump as a therapeutic target: making a "smart bomb" for prostate cancer.

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1165-73

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scholarly article

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3758021

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10.1593/NEO.09878

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11

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11

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Adrienne W Paton

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2009-11-01T00:00:00Z

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38060142

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19881952

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molecular chaperones

endoplasmic reticulum

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2767218

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