Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family
about
Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic functionImportance of glutamate 279 for the coenzyme binding of human glutamate dehydrogenaseHuman GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cellsThe discovery of human of GLUD2 glutamate dehydrogenase and its implications for cell function in health and diseaseMultiple Forms of Glutamate Dehydrogenase in Animals: Structural Determinants and Physiological ImplicationsEstrogen modification of human glutamate dehydrogenases is linked to enzyme activation state.A microarray analysis of the temporal response of liver to methylprednisolone: a comparative analysis of two dosing regimens.Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry)Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain.Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.Renal ammonia metabolism and transport.Gene Cloning and mRNA Expression of Glutamate Dehydrogenase in the Liver, Brain, and Intestine of the Swamp Eel, Monopterus albus (Zuiew), Exposed to Freshwater, Terrestrial Conditions, Environmental Ammonia, or Salinity Stress.Involvement of GDH3-encoded NADP+-dependent glutamate dehydrogenase in yeast cell resistance to stress-induced apoptosis in stationary phase cellsImport of a major mitochondrial enzyme depends on synergy between two distinct helices of its presequence.The Glutamate Dehydrogenase Pathway and Its Roles in Cell and Tissue Biology in Health and Disease.The role of glutamate dehydrogenase in mammalian ammonia metabolism.Heterogeneous cellular distribution of glutamate dehydrogenase in brain and in non-neural tissues.The odyssey of a young gene: structure-function studies in human glutamate dehydrogenases reveal evolutionary-acquired complex allosteric regulation mechanisms.Glutamate dehydrogenase isoforms with N-terminal (His)6- or FLAG-tag retain their kinetic properties and cellular localization.Nucleotide sequence of rat liver glutamate dehydrogenase cDNA.Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the activation of the enzyme by ADP and L-leucine.A membrane-bound form of glutamate dehydrogenase possesses an ATP-dependent high-affinity microtubule-binding activity.Leukocyte glutamate dehydrogenase in patients with degenerative neurological disorders.Cassette mutagenesis of lysine 130 of human glutamate dehydrogenase. An essential residue in catalysis.Identification of the GTP binding site of human glutamate dehydrogenase by cassette mutagenesis and photoaffinity labeling.Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.Hepatocyte swelling leads to rapid decrease of the G-/total actin ratio and increases actin mRNA levels.Riboflavin 5'-hydroxymethyl oxidation. Molecular cloning, expression, and glycoprotein nature of the 5'-aldehyde-forming enzyme from Schizophyllum commune.Different antigenic reactivities of bovine brain glutamate dehydrogenase isoproteins.Identification of an NAD+ binding site of brain glutamate dehydrogenase isoproteins by photoaffinity labeling.Activation of two types of brain glutamate dehydrogenase isoproteins by gabapentin.
P2860
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P2860
Isolation and characterization of cDNA clones encoding human liver glutamate dehydrogenase: evidence for a small gene family
description
1988 nî lūn-bûn
@nan
1988 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1988 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1988年の論文
@ja
1988年論文
@yue
1988年論文
@zh-hant
1988年論文
@zh-hk
1988年論文
@zh-mo
1988年論文
@zh-tw
1988年论文
@wuu
name
Isolation and characterization ...... idence for a small gene family
@ast
Isolation and characterization ...... idence for a small gene family
@en
Isolation and characterization ...... idence for a small gene family
@nl
type
label
Isolation and characterization ...... idence for a small gene family
@ast
Isolation and characterization ...... idence for a small gene family
@en
Isolation and characterization ...... idence for a small gene family
@nl
prefLabel
Isolation and characterization ...... idence for a small gene family
@ast
Isolation and characterization ...... idence for a small gene family
@en
Isolation and characterization ...... idence for a small gene family
@nl
P2093
P2860
P3181
P356
P1476
Isolation and characterization ...... idence for a small gene family
@en
P2093
A Mitsialis
A Plaitakis
G Mavrothalassitis
G Tzimagiorgis
J Papamatheakis
N Moschonas
P2860
P304
P3181
P356
10.1073/PNAS.85.10.3494
P407
P577
1988-05-01T00:00:00Z