BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome - Wikidata - awgldk - TriplyDB

BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome

BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome

http://www.wikidata.org/entity/Q24650899

about

The Werner syndrome protein is distinguished from the Bloom syndrome protein by its capacity to tightly bind diverse DNA structures Human single-stranded DNA binding proteins are essential for maintaining genomic stability RECQL5 cooperates with Topoisomerase II alpha in DNA decatenation and cell cycle progression Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication MHF1-MHF2, a histone-fold-containing protein complex, participates in the Fanconi anemia pathway via FANCM FAAP20: a novel ubiquitin-binding FA nuclear core-complex protein required for functional integrity of the FA-BRCA DNA repair pathway Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1 Scaffolding protein SPIDR/KIAA0146 connects the Bloom syndrome helicase with homologous recombination repair Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome The RecQ DNA helicases in DNA repair More complexity to the Bloom's syndrome complex RMI, a new OB-fold complex essential for Bloom syndrome protein to maintain genome stability Functions and regulation of the multitasking FANCM family of DNA motor proteins Telomere shortening in human diseases Structure and Cellular Roles of the RMI Core Complex from the Bloom Syndrome Dissolvasome Crystal structures of RMI1 and RMI2, two OB-fold regulatory subunits of the BLM complex Defining the molecular interface that connects the Fanconi anemia protein FANCM to the Bloom syndrome dissolvasome Structural and mechanistic insight into Holliday-junction dissolution by Topoisomerase IIIα and RMI1 Decatenation of DNA by the S. cerevisiae Sgs1-Top3-Rmi1 and RPA complex: a mechanism for disentangling chromosomes.Delineation of joint molecule resolution pathways in meiosis identifies a crossover-specific resolvase Oligonucleotide/oligosaccharide-binding fold proteins: a growing family of genome guardians Interplay between structure-specific endonucleases for crossover control during Caenorhabditis elegans meiosis Loss of RMI2 Increases Genome Instability and Causes a Bloom-Like Syndrome ETAA1 acts at stalled replication forks to maintain genome integrity ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions.Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes The RTR Complex Partner RMI2 and the DNA Helicase RTEL1 Are Both Independently Involved in Preserving the Stability of 45S rDNA Repeats in Arabidopsis thaliana.The G-quadruplex ligand telomestatin impairs binding of topoisomerase IIIalpha to G-quadruplex-forming oligonucleotides and uncaps telomeres in ALT cells WRN helicase defective in the premature aging disorder Werner syndrome genetically interacts with topoisomerase 3 and restores the top3 slow growth phenotype of sgs1 top3 TOPO3alpha influences antigenic variation by monitoring expression-site-associated VSG switching in Trypanosoma brucei.Regulation of FANCD2 and FANCI monoubiquitination by their interaction and by DNA.Distinct roles of RECQ1 in the maintenance of genomic stability.Human RECQ1 and RECQ4 helicases play distinct roles in DNA replication initiation Identification of Trypanosoma brucei RMI1/BLAP75 homologue and its roles in antigenic variation.PICH and BLM limit histone association with anaphase centromeric DNA threads and promote their resolution.The dissolution of double Holliday junctions.Escherichia coli RecG functionally suppresses human Bloom syndrome phenotypes Mus81 and Yen1 promote reciprocal exchange during mitotic recombination to maintain genome integrity in budding yeast.A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cells.Role of replication protein A in double holliday junction dissolution mediated by the BLM-Topo IIIα-RMI1-RMI2 protein complex

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P2860

BLAP18/RMI2, a novel OB-fold-containing protein, is an essential component of the Bloom helicase-double Holliday junction dissolvasome

http://www.wikidata.org/entity/Q24650899

description

2008 nî lūn-bûn

@nan

2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2008 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

2008年の論文

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2008年論文

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2008年論文

@zh-hant

2008年論文

@zh-hk

2008年論文

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2008年論文

@zh-tw

2008年论文

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name

BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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type

label

BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

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Genes & Development

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BLAP18/RMI2, a novel OB-fold-c ...... Holliday junction dissolvasome

@en

P2093

Abdullah Mahmood Ali

http://www.w3.org/2001/XMLSchema#string

Amom Ruhikanta Meetei

http://www.w3.org/2001/XMLSchema#string

Chang-hu Du

http://www.w3.org/2001/XMLSchema#string

Patrick Sung

http://www.w3.org/2001/XMLSchema#string

Paul R Andreassen

http://www.w3.org/2001/XMLSchema#string

Qiang Fan

http://www.w3.org/2001/XMLSchema#string

Steven Raynard

http://www.w3.org/2001/XMLSchema#string

Thiyam Ramsing Singh

http://www.w3.org/2001/XMLSchema#string

Valeria Busygina

http://www.w3.org/2001/XMLSchema#string

P2860

Replication protein A physically interacts with the Bloom's syndrome protein and stimulates its helicase activity

BLAP75, an essential component of Bloom's syndrome protein complexes that maintain genome integrity

FAAP100 is essential for activation of the Fanconi anemia-associated DNA damage response pathway

The Bloom's syndrome gene product is homologous to RecQ helicases

BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates

MPS1-dependent mitotic BLM phosphorylation is important for chromosome stability

BASC, a super complex of BRCA1-associated proteins involved in the recognition and repair of aberrant DNA structures

A multiprotein nuclear complex connects Fanconi anemia and Bloom syndrome

RECQL5/Recql5 helicase regulates homologous recombination and suppresses tumor formation via disruption of Rad51 presynaptic filaments

Bloom's syndrome. I. Genetical and clinical observations in the first twenty-seven patients

P304

2856-68

http://www.w3.org/2001/XMLSchema#string

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scholarly article

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2911823

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P356

10.1101/GAD.1725108

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P407

P433

20

http://www.w3.org/2001/XMLSchema#string

P478

22

http://www.w3.org/2001/XMLSchema#string

P577

2008-10-15T00:00:00Z

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P5875

23385226

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P698

18923083

http://www.w3.org/2001/XMLSchema#string

P921

OB-fold nucleic acid binding domain

protein folding

P932

2569884

http://www.w3.org/2001/XMLSchema#string