The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response - Wikidata - awgldk - TriplyDB

The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response

The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response

http://www.wikidata.org/entity/Q24652479

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The proteasomal de-ubiquitinating enzyme POH1 promotes the double-strand DNA break response The Rap80-BRCC36 de-ubiquitinating enzyme complex antagonizes RNF8-Ubc13-dependent ubiquitination events at DNA double strand breaks MERIT40 controls BRCA1-Rap80 complex integrity and recruitment to DNA double-strand breaks BBAP monoubiquitylates histone H4 at lysine 91 and selectively modulates the DNA damage response Genome-wide association studies identify loci associated with age at menarche and age at natural menopause BMI1-mediated histone ubiquitylation promotes DNA double-strand break repair Orchestration of the DNA-damage response by the RNF8 ubiquitin ligase RAP80 interacts with the SUMO-conjugating enzyme UBC9 and is a novel target for sumoylation Writers, Readers, and Erasers of Histone Ubiquitylation in DNA Double-Strand Break Repair Role of Deubiquitinating Enzymes in DNA Repair Predictive models for customizing chemotherapy in advanced non-small cell lung cancer (NSCLC)Conformational Dynamics and Structural Plasticity Play Critical Roles in the Ubiquitin Recognition of a UIM Domain Structural basis for specific recognition of Lys 63-linked polyubiquitin chains by tandem UIMs of RAP80 Histone ubiquitination associates with BRCA1-dependent DNA damage response Ube2w and ataxin-3 coordinately regulate the ubiquitin ligase CHIP Customized treatment in non-small-cell lung cancer based on EGFR mutations and BRCA1 mRNA expression.Evolutionary history of the poly(ADP-ribose) polymerase gene family in eukaryotes.USP13 regulates the RAP80-BRCA1 complex dependent DNA damage response.Sensitivity to poly(ADP-ribose) polymerase (PARP) inhibition identifies ubiquitin-specific peptidase 11 (USP11) as a regulator of DNA double-strand break repair.Mutations in the BRCT binding site of BRCA1 result in hyper-recombination BCL10 regulates RNF8/RNF168-mediated ubiquitination in the DNA damage response.BRCA1 and BRCA2: breast/ovarian cancer susceptibility gene products and participants in DNA double-strand break repair.Differential regulation of JAMM domain deubiquitinating enzyme activity within the RAP80 complex.Cul4A is essential for spermatogenesis and male fertility.BRCA1-directed, enhanced and aberrant homologous recombination: mechanism and potential treatment strategies.The RING finger protein RNF8 ubiquitinates Nbs1 to promote DNA double-strand break repair by homologous recombination.A bioinformatics filtering strategy for identifying radiation response biomarker candidates.Time to bloom.Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining.PARP1-driven poly-ADP-ribosylation regulates BRCA1 function in homologous recombination-mediated DNA repair.RAP80-directed tuning of BRCA1 homologous recombination function at ionizing radiation-induced nuclear foci.The BRCA1-RAP80 complex regulates DNA repair mechanism utilization by restricting end resection.RNF8-independent Lys63 poly-ubiquitylation prevents genomic instability in response to replication-associated DNA damage.BRCA1 A‐complex fine tunes repair functions of BRCA1.Combinatory effect of BRCA1 and HERC2 expression on outcome in advanced non-small-cell lung cancer.RAP80 protein is important for genomic stability and is required for stabilizing BRCA1-A complex at DNA damage sites in vivo INT6/EIF3E Controls the RNF8-Dependent Ubiquitylation Pathway and Facilitates DNA Double-Strand Break Repair in Human Cells.Ubiquitin-H2AX fusions render 53BP1 recruitment to DNA damage sites independent of RNF8 or RNF168 RAP80 is critical in maintaining genomic stability and suppressing tumor development.TRAIP/RNF206 is required for recruitment of RAP80 to sites of DNA damage.

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The ubiquitin-interacting motif containing protein RAP80 interacts with BRCA1 and functions in DNA damage repair response

http://www.wikidata.org/entity/Q24652479

description

2007 nî lūn-bûn

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2007 թուականի Յուլիսին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի հուլիսին հրատարակված գիտական հոդված

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2007年の論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年論文

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2007年论文

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name

The ubiquitin-interacting moti ...... in DNA damage repair response

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The ubiquitin-interacting moti ...... in DNA damage repair response

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The ubiquitin-interacting moti ...... in DNA damage repair response

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type

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The ubiquitin-interacting moti ...... in DNA damage repair response

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The ubiquitin-interacting moti ...... in DNA damage repair response

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The ubiquitin-interacting moti ...... in DNA damage repair response

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The ubiquitin-interacting moti ...... in DNA damage repair response

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The ubiquitin-interacting moti ...... in DNA damage repair response

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The ubiquitin-interacting moti ...... in DNA damage repair response

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0008-5472.CAN-07-0924

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Cancer Research

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The ubiquitin-interacting moti ...... in DNA damage repair response

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Fen Xia

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Grace Liao

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Jun Yan

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Li-Ping Li

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Xiao-Ping Yang

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Yong-Sik Kim

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P2860

MDC1 is a mediator of the mammalian DNA damage checkpoint

The BRCT domain is a phospho-protein binding domain

RAP80, a novel nuclear protein that interacts with the retinoid-related testis-associated receptor

ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

Chk2 phosphorylation of BRCA1 regulates DNA double-strand break repair

BRCA1: cell cycle checkpoint, genetic instability, DNA damage response and cancer evolution

Structure of the ubiquitin-interacting motif of S5a bound to the ubiquitin-like domain of HR23B

Regulation of monoubiquitinated PCNA by DUB autocleavage

Substrate specificities and identification of putative substrates of ATM kinase family members

Genetic analysis of BRCA1 function in a defined tumor cell line

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10.1158/0008-5472.CAN-07-0924

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14

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67

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Anton M. Jetten

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17621610

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2391092

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