RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences - Wikidata - awgldk - TriplyDB

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

http://www.wikidata.org/entity/Q24652493

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KIF14 negatively regulates Rap1a-Radil signaling during breast cancer progression Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse Concerning immune synapses: a spatiotemporal timeline Platelet signaling Talin Dependent Mechanosensitivity of Cell Focal Adhesions Integrin-beta3 clusters recruit clathrin-mediated endocytic machinery in the absence of traction force.Rap1 can bypass the FAK-Src-Paxillin cascade to induce cell spreading and focal adhesion formation The Structure of an Interdomain Complex That Regulates Talin Activity Structure of a double ubiquitin-like domain in the talin head: a role in integrin activation The Structure of the Talin Head Reveals a Novel Extended Conformation of the FERM Domain Rap1-interacting adapter molecule (RIAM) associates with the plasma membrane via a proximity detector RIAM and Vinculin Binding to Talin Are Mutually Exclusive and Regulate Adhesion Assembly and Turnover Crystal structure of Lamellipodin implicates diverse functions in actin polymerization and Ras signaling Structural Basis for Small G Protein Effector Interaction of Ras-related Protein 1 (Rap1) and Adaptor Protein Krev Interaction Trapped 1 (KRIT1)The structure of Rap1 in complex with RIAM reveals specificity determinants and recruitment mechanism All Subdomains of the Talin Rod Are Mechanically Vulnerable and May Contribute To Cellular Mechanosensing Skap2 is required for β2 integrin-mediated neutrophil recruitment and functions.The N terminus of SKAP55 enables T cell adhesion to TCR and integrin ligands via distinct mechanisms.A RIAM/lamellipodin-talin-integrin complex forms the tip of sticky fingers that guide cell migration A plastic relationship between vinculin-mediated tension and adhesion complex area defines adhesion size and lifetime.Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1.Distinct roles for talin-1 and kindlin-3 in LFA-1 extension and affinity regulation.Two modes of integrin activation form a binary molecular switch in adhesion maturation WNK1 kinase balances T cell adhesion versus migration in vivo Platelet 12-LOX is essential for FcγRIIa-mediated platelet activation.Recreation of the terminal events in physiological integrin activation.Pannexin- and Connexin-Mediated Intercellular Communication in Platelet Function.HPK1 associates with SKAP-HOM to negatively regulate Rap1-mediated B-lymphocyte adhesion.Control of cell adhesion dynamics by Rap1 signaling.Significance of talin in cancer progression and metastasis.Alpha v beta3 integrin spatially regulates VASP and RIAM to control adhesion dynamics and migration.Mechanical stability of talin rod controls cell migration and substrate sensing.Optimization of formaldehyde cross-linking for protein interaction analysis of non-tagged integrin beta1 Talins and kindlins: partners in integrin-mediated adhesion.Effects of high glucose on integrin activity and fibronectin matrix assembly by mesangial cells The final steps of integrin activation: the end game Kindlins, integrin activation and the regulation of talin recruitment to αIIbβ3.Studies on the morphology and spreading of human endothelial cells define key inter- and intramolecular interactions for talin1.Binding properties and stability of the Ras-association domain of Rap1-GTP interacting adapter molecule (RIAM).New isoform-specific monoclonal antibodies reveal different sub-cellular localisations for talin1 and talin2.

P2860

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P2860

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

http://www.wikidata.org/entity/Q24652493

description

2009 nî lūn-bûn

@nan

2009 թուականի Փետրուարին հրատարակուած գիտական յօդուած

@hyw

2009 թվականի փետրվարին հրատարակված գիտական հոդված

@hy

2009年の論文

@ja

2009年論文

@yue

2009年論文

@zh-hant

2009年論文

@zh-hk

2009年論文

@zh-mo

2009年論文

@zh-tw

2009年论文

@wuu

name

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@ast

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@en

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@nl

type

label

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@ast

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@en

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@nl

prefLabel

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@ast

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@en

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@nl

P1433

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P1433

Journal of Biological Chemistry

P1476

RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences

@en

P2093

Ho-Sup Lee

http://www.w3.org/2001/XMLSchema#string

Mark H Ginsberg

http://www.w3.org/2001/XMLSchema#string

Sanford J Shattil

http://www.w3.org/2001/XMLSchema#string

Wilma Puzon-McLaughlin

http://www.w3.org/2001/XMLSchema#string

P2860

Structural determinants of integrin recognition by talin

Structural basis of integrin activation by talin

RAPL, a Rap1-binding molecule that mediates Rap1-induced adhesion through spatial regulation of LFA-1

Vinculin activation by talin through helical bundle conversion

Integrins: bidirectional, allosteric signaling machines

Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamics

RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesion

Phosphoinositide 3-kinase inhibition spares actin assembly in activating platelets but reverses platelet aggregation

Talin binding to integrin beta tails: a final common step in integrin activation

Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III.

P304

5119-27

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scholarly article

P3181

1192496

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P356

10.1074/JBC.M807117200

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P407

P433

8

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P478

284

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P50

Chinten James Lim

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2009-02-20T00:00:00Z

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19098287

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P932

2643525

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